SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ix6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		7 / 12 HIS A  51
LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.96A 1axwA-3ix6A:
35.4		 1axwA-3ix6A:
47.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.57A 1axwB-3ix6A:
35.5		 1axwB-3ix6A:
47.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 LEU A 143
ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.66A 1b02A-3ix6A:
30.0		 1b02A-3ix6A:
33.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 GLU A  58
ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.90A 1hvyC-3ix6A:
33.8		 1hvyC-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 GLU A  58
ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.89A 1i00A-3ix6A:
33.7		 1i00A-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 GLU A  58
ILE A  79
TRP A  80
ASP A 169
TYR A 209
 None
 0.91A 1i00A-3ix6A:
33.7		 1i00A-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.78A 1i00B-3ix6A:
33.9		 1i00B-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 ILE A  79
ASP A 169
GLY A 173
ASN A 177
TYR A 209
 None
 0.52A 1i00B-3ix6A:
33.9		 1i00B-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 1.30A 1i00B-3ix6A:
33.9		 1i00B-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.53A 1ju6A-3ix6A:
33.0		 1ju6A-3ix6A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.53A 1ju6C-3ix6A:
32.9		 1ju6C-3ix6A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.49A 1jujA-3ix6A:
32.5		 1jujA-3ix6A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.49A 1jujB-3ix6A:
32.5		 1jujB-3ix6A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.49A 1jujC-3ix6A:
32.5		 1jujC-3ix6A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.49A 1jujD-3ix6A:
32.5		 1jujD-3ix6A:
44.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 8 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.78A 1rtsA-3ix6A:
33.7		 1rtsA-3ix6A:
41.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.62A 1rtsB-3ix6A:
33.6		 1rtsB-3ix6A:
41.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 HIS A  51
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.82A 1tlsA-3ix6A:
35.3		 1tlsA-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 HIS A  51
LEU A 143
LEU A 172
GLY A 173
PHE A 176
 None
 0.98A 1tlsB-3ix6A:
35.4		 1tlsB-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 HIS A  51
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.75A 1tlsB-3ix6A:
35.4		 1tlsB-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 HIS A  51
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.80A 1tsnA-3ix6A:
35.3		 1tsnA-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TSN_A_C2FA266_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.86A 1tsnA-3ix6A:
35.3		 1tsnA-3ix6A:
48.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A  45
LEU A   5
LEU A   7
ILE A 208
HIS A 212
 None
 1.00A 2j7xA-3ix6A:
undetectable		 2j7xA-3ix6A:
22.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ASP A 169
GLY A 173
TYR A 209
 None
 0.72A 2kceA-3ix6A:
35.4		 2kceA-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
LEU A 143
ASP A 169
GLY A 173
 None
 1.02A 2kceA-3ix6A:
35.4		 2kceA-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.81A 2kceB-3ix6A:
35.6		 2kceB-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
 None
 1.07A 2kceB-3ix6A:
35.6		 2kceB-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.75A 2kceB-3ix6A:
35.6		 2kceB-3ix6A:
48.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.77A 2tsrA-3ix6A:
33.6		 2tsrA-3ix6A:
41.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 GLU A  58
ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.78A 2tsrC-3ix6A:
33.0		 2tsrC-3ix6A:
41.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 GLN A 165
VAL A 174
ILE A 208
VAL A  11
VAL A  29
 None
 1.40A 3fi0C-3ix6A:
undetectable		 3fi0C-3ix6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 GLN A 165
VAL A 174
ILE A 208
VAL A  11
VAL A  29
 None
 1.44A 3fi0F-3ix6A:
undetectable		 3fi0F-3ix6A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 GLN A 165
VAL A 174
ILE A 208
VAL A  11
VAL A  29
 None
 1.41A 3fi0H-3ix6A:
undetectable		 3fi0H-3ix6A:
22.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.34A 3k2hA-3ix6A:
32.8		 3k2hA-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
 None
 0.77A 3k2hA-3ix6A:
32.8		 3k2hA-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ILE A  79
TRP A  80
LEU A 143
 None
 0.76A 3k2hA-3ix6A:
32.8		 3k2hA-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.34A 3k2hB-3ix6A:
33.4		 3k2hB-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
 None
 0.73A 3k2hB-3ix6A:
33.4		 3k2hB-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ILE A  79
TRP A  80
LEU A 143
 None
 0.78A 3k2hB-3ix6A:
33.4		 3k2hB-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.47A 3nrrA-3ix6A:
10.9		 3nrrA-3ix6A:
34.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.50A 3nrrB-3ix6A:
33.7		 3nrrB-3ix6A:
34.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A   8
HIS A 201
LEU A  45
PRO A 175
LEU A   5
 None
 1.37A 3okxA-3ix6A:
undetectable		 3okxA-3ix6A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A   8
HIS A 201
LEU A  45
PRO A 175
LEU A   5
 None
 1.34A 3okxB-3ix6A:
undetectable		 3okxB-3ix6A:
19.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 HIS A 147
LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 0.70A 3uwlB-3ix6A:
35.2		 3uwlB-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 LEU A 143
HIS A 147
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.89A 3uwlB-3ix6A:
35.2		 3uwlB-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 HIS A 147
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.71A 3uwlD-3ix6A:
33.4		 3uwlD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
HIS A 147
LEU A 172
GLY A 173
PHE A 176
 None
 0.92A 3uwlD-3ix6A:
33.4		 3uwlD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.56A 3uwlD-3ix6A:
33.4		 3uwlD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.69A 4eb4A-3ix6A:
33.2		 4eb4A-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 1.19A 4eb4A-3ix6A:
33.2		 4eb4A-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.68A 4eb4B-3ix6A:
33.1		 4eb4B-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 1.17A 4eb4B-3ix6A:
33.1		 4eb4B-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.83A 4eb4C-3ix6A:
33.4		 4eb4C-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 ILE A  79
ASP A 169
GLY A 173
ASN A 177
TYR A 209
 None
 0.60A 4eb4C-3ix6A:
33.4		 4eb4C-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 1.30A 4eb4C-3ix6A:
33.4		 4eb4C-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.73A 4eb4D-3ix6A:
33.5		 4eb4D-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ILE A  79
ASP A 169
GLY A 173
ASN A 177
TYR A 209
 None
 0.59A 4eb4D-3ix6A:
33.5		 4eb4D-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 1.26A 4eb4D-3ix6A:
33.5		 4eb4D-3ix6A:
42.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 HIS A  51
ASP A 169
GLY A 173
PHE A 176
TYR A 209
 None
 0.88A 4fogA-3ix6A:
35.7		 4fogA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 LEU A 143
ASP A 169
GLY A 173
PHE A 176
TYR A 209
 None
 0.69A 4fogA-3ix6A:
35.7		 4fogA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 SER A  54
LEU A 143
ASP A 169
GLY A 173
TYR A 209
 None
 0.86A 4fogA-3ix6A:
35.7		 4fogA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 11 HIS A  51
LEU A 143
ASP A 169
GLY A 173
PHE A 176
TYR A 209
 None
 1.06A 4fogC-3ix6A:
35.5		 4fogC-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 SER A  54
LEU A 143
ASP A 169
GLY A 173
TYR A 209
 None
 1.12A 4fogC-3ix6A:
35.5		 4fogC-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 11 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.74A 4fogD-3ix6A:
35.5		 4fogD-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 HIS A  51
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.83A 4foxA-3ix6A:
35.8		 4foxA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.89A 4foxA-3ix6A:
35.8		 4foxA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ILE A  79
TRP A  80
TRP A  83
 None
 0.59A 4foxA-3ix6A:
35.8		 4foxA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 SER A  54
GLU A  58
LEU A 143
ASP A 169
GLY A 173
TYR A 209
 None
 1.06A 4foxA-3ix6A:
35.8		 4foxA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
TRP A  80
TRP A  83
LEU A 143
 None
 0.74A 4foxA-3ix6A:
35.8		 4foxA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.52A 4foxB-3ix6A:
35.8		 4foxB-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
ASP A 169
GLY A 173
PHE A 176
TYR A 209
 None
 0.79A 4foxB-3ix6A:
35.8		 4foxB-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ILE A  79
ASP A 169
GLY A 173
 None
 0.94A 4foxB-3ix6A:
35.8		 4foxB-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 SER A  54
GLU A  58
LEU A 143
ASP A 169
GLY A 173
TYR A 209
 None
 1.00A 4foxB-3ix6A:
35.8		 4foxB-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 11 HIS A  51
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.79A 4foxC-3ix6A:
35.3		 4foxC-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 SER A  54
GLU A  58
ASP A 169
GLY A 173
TYR A 209
 None
 0.81A 4foxC-3ix6A:
35.3		 4foxC-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 SER A  54
GLU A  58
LEU A 143
ASP A 169
GLY A 173
 None
 1.08A 4foxC-3ix6A:
35.3		 4foxC-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 SER A  54
GLU A  58
TRP A  80
TRP A  83
LEU A 143
 None
 0.73A 4foxC-3ix6A:
35.3		 4foxC-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.42A 4foxD-3ix6A:
35.5		 4foxD-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 HIS A  51
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.79A 4foxE-3ix6A:
35.9		 4foxE-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ASP A 169
GLY A 173
TYR A 209
 None
 0.82A 4foxE-3ix6A:
35.9		 4foxE-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ILE A  79
ASP A 169
TYR A 209
 None
 0.96A 4foxE-3ix6A:
35.9		 4foxE-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 SER A  54
GLU A  58
ILE A  79
TRP A  80
TRP A  83
 None
 0.61A 4foxE-3ix6A:
35.9		 4foxE-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 HIS A  51
ASP A 169
GLY A 173
PHE A 176
TYR A 209
 None
 0.79A 4foxF-3ix6A:
35.7		 4foxF-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 HIS A  51
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.78A 4foxG-3ix6A:
35.4		 4foxG-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.85A 4foxG-3ix6A:
35.4		 4foxG-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 SER A  54
GLU A  58
LEU A 143
ASP A 169
GLY A 173
TYR A 209
 None
 1.07A 4foxG-3ix6A:
35.4		 4foxG-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 HIS A  51
ASP A 169
GLY A 173
PHE A 176
TYR A 209
 None
 0.85A 4foxH-3ix6A:
35.3		 4foxH-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 HIS A  51
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.80A 4fqsA-3ix6A:
35.4		 4fqsA-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 HIS A  51
ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.82A 4fqsB-3ix6A:
35.4		 4fqsB-3ix6A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.85A 4iqqA-3ix6A:
32.5		 4iqqA-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.62A 4iqqA-3ix6A:
32.5		 4iqqA-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.85A 4iqqB-3ix6A:
32.4		 4iqqB-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.50A 4iqqB-3ix6A:
32.4		 4iqqB-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.77A 4iqqC-3ix6A:
32.6		 4iqqC-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.45A 4iqqC-3ix6A:
32.6		 4iqqC-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 8 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.75A 4iqqD-3ix6A:
32.3		 4iqqD-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 8 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.57A 4iqqD-3ix6A:
32.3		 4iqqD-3ix6A:
38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 5 ILE A 170
VAL A 174
PHE A  42
HIS A  10
 None
 1.33A 4rzvA-3ix6A:
undetectable		 4rzvA-3ix6A:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_A_D16A401_1
(ORF70)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.55A 5h3aA-3ix6A:
33.4		 5h3aA-3ix6A:
43.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.82A 5h3aB-3ix6A:
33.5		 5h3aB-3ix6A:
43.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.48A 5j7wC-3ix6A:
35.1		 5j7wC-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
TYR A 209
 None
 0.40A 5j7wD-3ix6A:
34.8		 5j7wD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
ASP A 169
LEU A 172
GLY A 173
PHE A 176
 None
 0.76A 5j7wD-3ix6A:
34.8		 5j7wD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.86A 5nooA-3ix6A:
32.8		 5nooA-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.62A 5nooA-3ix6A:
32.8		 5nooA-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.86A 5nooB-3ix6A:
32.8		 5nooB-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.49A 5nooB-3ix6A:
32.8		 5nooB-3ix6A:
38.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 6 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.86A 5nooC-3ix6A:
32.9		 5nooC-3ix6A:
38.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 MET A 186
ALA A 182
SER A 180
LEU A  59
ILE A  56
 None
 1.27A 5vlmB-3ix6A:
undetectable		 5vlmB-3ix6A:
21.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 7 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.74A 5x5qC-3ix6A:
33.7		 5x5qC-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 8 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.74A 5x5qD-3ix6A:
33.8		 5x5qD-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 6 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.72A 5x5qE-3ix6A:
33.8		 5x5qE-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 6 ILE A  79
ASP A 169
GLY A 173
TYR A 209
 None
 0.67A 5x5qE-3ix6A:
33.8		 5x5qE-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		4 / 8 ASP A 169
LEU A 172
GLY A 173
TYR A 209
 None
 0.74A 5x5qF-3ix6A:
33.7		 5x5qF-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.29A 5x66A-3ix6A:
33.7
5x66B-3ix6A:
33.7		 5x66A-3ix6A:
41.32
5x66B-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 ILE A  79
ASP A 169
GLY A 173
ASN A 177
TYR A 209
 None
 0.62A 5x66A-3ix6A:
33.7
5x66B-3ix6A:
33.7		 5x66A-3ix6A:
41.32
5x66B-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 ASP A 169
LEU A 172
GLY A 173
ASN A 177
TYR A 209
 None
 0.34A 5x66C-3ix6A:
33.7		 5x66C-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 9 ILE A  79
ASP A 169
GLY A 173
ASN A 177
TYR A 209
 None
 0.64A 5x66C-3ix6A:
33.7		 5x66C-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 10 ILE A  79
ASP A 169
GLY A 173
ASN A 177
TYR A 209
 None
 0.63A 5x66D-3ix6A:
33.9		 5x66D-3ix6A:
41.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.66A 6qxsB-3ix6A:
33.3		 6qxsB-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QXS_B_FOZB403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 0.52A 6qxsB-3ix6A:
33.3		 6qxsB-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.57A 6qyaD-3ix6A:
32.7		 6qyaD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 0.40A 6qyaD-3ix6A:
32.7		 6qyaD-3ix6A:
41.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		6 / 12 ASP A 169
LEU A 172
GLY A 173
PHE A 176
ASN A 177
TYR A 209
 None
 0.48A 6r2eA-3ix6A:
32.9		 6r2eA-3ix6A:
45.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.71A 6r2eA-3ix6A:
32.9		 6r2eA-3ix6A:
45.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 LEU A 143
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.66A 6r2eE-3ix6A:
32.7		 6r2eE-3ix6A:
45.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 12 TYR A  94
LEU A 143
GLY A 173
PHE A 176
ASN A 177
 None
 0.83A 6r2eE-3ix6A:
32.7		 6r2eE-3ix6A:
45.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 3ix6 THYMIDYLATE SYNTHASE
(Brucella
melitensis) 		5 / 11 LEU A 143
LEU A 172
GLY A 173
PHE A 176
ASN A 177
 None
 0.73A 6r2eG-3ix6A:
32.8		 6r2eG-3ix6A:
45.67