SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ix7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		3 / 3 TRP A 169
ALA A 235
VAL A 144
 None
 0.97A 2izqC-3ix7A:
undetectable
2izqD-3ix7A:
undetectable		 2izqC-3ix7A:
20.00
2izqD-3ix7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		5 / 9 ARG A 202
VAL A 155
LEU A 164
ALA A 206
ALA A 160
 None
 1.38A 3ax7B-3ix7A:
undetectable		 3ax7B-3ix7A:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		5 / 11 LEU A 225
VAL A 149
SER A 148
LEU A 150
LEU A 243
 None
 1.03A 4or0B-3ix7A:
undetectable		 4or0B-3ix7A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		5 / 12 LEU A 150
LYS A 253
ILE A 257
VAL A 155
LEU A 209
 None
 1.10A 4y0pA-3ix7A:
undetectable		 4y0pA-3ix7A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		4 / 6 PHE A 181
THR A 147
ASP A 152
GLY A 153
 None
 1.21A 5mraA-3ix7A:
undetectable
5mraB-3ix7A:
undetectable		 5mraA-3ix7A:
22.86
5mraB-3ix7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		5 / 12 VAL A 149
VAL A 170
LEU A 175
LEU A 197
LEU A 200
 None
 1.11A 6ajiA-3ix7A:
undetectable		 6ajiA-3ix7A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		4 / 6 MET A 246
GLY A 251
ALA A 229
LEU A 236
 None
 1.09A 6fosA-3ix7A:
undetectable		 6fosA-3ix7A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3ix7 UNCHARACTERIZED
PROTEIN TTHA0540
(Thermus
thermophilus) 		4 / 6 MET A 246
ALA A 229
LEU A 236
ALA A 254
 None
 1.16A 6fosB-3ix7A:
undetectable		 6fosB-3ix7A:
17.16