SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ixw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 6 VAL A 388
ASN A 446
ILE A 497
ASN A 495
 None
 0.98A 1e06A-3ixwA:
undetectable		 1e06A-3ixwA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 5 PHE A 368
GLY A 194
SER A 308
PHE A 197
 None
 1.25A 1icuC-3ixwA:
undetectable
1icuD-3ixwA:
undetectable		 1icuC-3ixwA:
14.49
1icuD-3ixwA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 VAL A  94
ARG A  99
VAL A  61
LEU A  53
ALA A  56
 None
 1.28A 1n4hA-3ixwA:
undetectable		 1n4hA-3ixwA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 8 LEU A 553
THR A 405
ILE A 395
TYR A 440
 None
 1.04A 1qvtA-3ixwA:
undetectable		 1qvtA-3ixwA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 PHE A 624
GLU A 211
TYR A 159
LEU A 433
 None
 1.19A 1rmtB-3ixwA:
undetectable		 1rmtB-3ixwA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 HIS A 560
ASP A 484
ASN A 500
 None
 0.87A 1wg8B-3ixwA:
undetectable		 1wg8B-3ixwA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 THR A  43
GLU A  55
HIS A  49
 None
 0.85A 1xwfA-3ixwA:
undetectable		 1xwfA-3ixwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 THR A  43
GLU A  55
HIS A  49
 None
 0.88A 1xwfB-3ixwA:
undetectable		 1xwfB-3ixwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 THR A  43
GLU A  55
HIS A  49
 None
 0.91A 1xwfC-3ixwA:
undetectable		 1xwfC-3ixwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 THR A  43
GLU A  55
HIS A  49
 None
 0.86A 1xwfD-3ixwA:
undetectable		 1xwfD-3ixwA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 12 PRO A 597
ILE A 442
SER A 454
VAL A 390
LEU A 490
 None
 1.20A 1z9hD-3ixwA:
0.5		 1z9hD-3ixwA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 SER A 524
GLU A 529
ASP A 585
 None
 0.83A 2avdB-3ixwA:
undetectable		 2avdB-3ixwA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C7V_B_MTXB1272_1
(PTERIDINE REDUCTASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 12 ARG A 207
SER A 579
PRO A 597
LEU A 460
GLU A 552
 None
 1.48A 2c7vB-3ixwA:
undetectable		 2c7vB-3ixwA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C7V_C_MTXC1272_1
(PTERIDINE REDUCTASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 12 ARG A 207
SER A 579
PRO A 597
LEU A 460
GLU A 552
 None
 1.47A 2c7vC-3ixwA:
undetectable		 2c7vC-3ixwA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 6 TYR A 588
TYR A 199
GLY A 582
TYR A 580
 None
 1.27A 2g72A-3ixwA:
undetectable		 2g72A-3ixwA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 ASP A 191
ARG A 192
ARG A 587
 None
 1.06A 2j9dA-3ixwA:
undetectable
2j9dC-3ixwA:
undetectable		 2j9dA-3ixwA:
11.80
2j9dC-3ixwA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.70A 2zweA-3ixwA:
8.5
2zweB-3ixwA:
undetectable		 2zweA-3ixwA:
18.40
2zweB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.55A 2zweA-3ixwA:
8.5
2zweB-3ixwA:
undetectable		 2zweA-3ixwA:
18.40
2zweB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.73A 2zwfA-3ixwA:
8.5
2zwfB-3ixwA:
undetectable		 2zwfA-3ixwA:
18.40
2zwfB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.62A 2zwfA-3ixwA:
8.5
2zwfB-3ixwA:
undetectable		 2zwfA-3ixwA:
18.40
2zwfB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.75A 2zwgA-3ixwA:
8.5
2zwgB-3ixwA:
undetectable		 2zwgA-3ixwA:
18.40
2zwgB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.67A 2zwgA-3ixwA:
8.5
2zwgB-3ixwA:
undetectable		 2zwgA-3ixwA:
18.40
2zwgB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 174
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.99A 2zwgA-3ixwA:
8.5
2zwgB-3ixwA:
undetectable		 2zwgA-3ixwA:
18.40
2zwgB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 174
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.85A 2zwgA-3ixwA:
8.5
2zwgB-3ixwA:
undetectable		 2zwgA-3ixwA:
18.40
2zwgB-3ixwA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_C_FOLC270_0
(PTERIDINE REDUCTASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 12 ARG A 207
SER A 579
PRO A 597
LEU A 460
GLU A 552
 None
 1.25A 3bmcC-3ixwA:
undetectable		 3bmcC-3ixwA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 12 THR A 106
LEU A 517
VAL A 113
GLY A 417
GLN A 111
 None
 1.13A 3ijdA-3ixwA:
undetectable		 3ijdA-3ixwA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 6 ARG A 117
SER A 349
GLY A  86
GLU A  55
 None
 1.09A 3k9fA-3ixwA:
undetectable
3k9fB-3ixwA:
undetectable
3k9fD-3ixwA:
undetectable		 3k9fA-3ixwA:
22.41
3k9fB-3ixwA:
22.41
3k9fD-3ixwA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 SER A 545
PHE A 551
LYS A 621
 None
 1.02A 3u88A-3ixwA:
undetectable		 3u88A-3ixwA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 ASP A 354
GLU A 231
GLY A 232
 None
 0.62A 3w9tA-3ixwA:
undetectable		 3w9tA-3ixwA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		3 / 3 ASP A 284
LYS A 285
ASP A 286
 None
 0.79A 4a7tA-3ixwA:
3.2		 4a7tA-3ixwA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 8 PHE A 363
HIS A 224
GLU A 228
ARG A 270
 None
 1.26A 4cx7A-3ixwA:
undetectable
4cx7B-3ixwA:
undetectable		 4cx7A-3ixwA:
21.82
4cx7B-3ixwA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 ILE A 305
LEU A 292
ASP A 299
GLY A 194
PHE A 197
 None
 1.33A 4fogA-3ixwA:
undetectable		 4fogA-3ixwA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 ILE A 305
LEU A 292
ASP A 299
GLY A 194
PHE A 197
 None
 1.23A 4fogC-3ixwA:
undetectable		 4fogC-3ixwA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 ILE A 305
LEU A 292
ASP A 299
GLY A 194
PHE A 197
 None
 1.31A 4foxF-3ixwA:
undetectable		 4foxF-3ixwA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 170
HIS A 321
ASN A 322
HIS A 325
 None
 0.59A 4p6sA-3ixwA:
8.2		 4p6sA-3ixwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 170
HIS A 321
ASN A 322
HIS A 325
 None
 0.60A 4p6sB-3ixwA:
8.4		 4p6sB-3ixwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 ARG A 270
PHE A 363
HIS A 224
GLU A 228
 None
 1.16A 5ad9A-3ixwA:
undetectable
5ad9B-3ixwA:
undetectable		 5ad9A-3ixwA:
20.50
5ad9B-3ixwA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 12 ASP A 563
THR A 455
ILE A 508
ARG A 192
TYR A 588
 None
 1.42A 5dlvA-3ixwA:
undetectable		 5dlvA-3ixwA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 5 GLU A 436
GLU A 537
THR A 507
LEU A 483
 None
 1.24A 5hm8G-3ixwA:
2.8		 5hm8G-3ixwA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 170
HIS A 321
ASN A 322
HIS A 325
 None
 0.58A 5i3aA-3ixwA:
8.1		 5i3aA-3ixwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 170
HIS A 321
ASN A 322
HIS A 325
 None
 0.58A 5i3aB-3ixwA:
8.0		 5i3aB-3ixwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 170
HIS A 321
ASN A 322
HIS A 325
 None
 0.63A 5i3bA-3ixwA:
7.9		 5i3bA-3ixwA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 10 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.79A 5m8nA-3ixwA:
6.6		 5m8nA-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 10 HIS A 170
HIS A 321
HIS A 325
THR A 348
SER A 351
 None
 0.92A 5m8nA-3ixwA:
6.6		 5m8nA-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		6 / 10 HIS A 170
HIS A 321
ASN A 322
HIS A 325
THR A 348
SER A 351
 None
 0.98A 5m8nB-3ixwA:
7.0		 5m8nB-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 10 HIS A 174
HIS A 321
ASN A 322
HIS A 325
THR A 348
 None
 1.21A 5m8nB-3ixwA:
7.0		 5m8nB-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 9 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.85A 5m8nC-3ixwA:
6.8		 5m8nC-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 9 HIS A 170
HIS A 321
HIS A 325
THR A 348
SER A 351
 None
 1.00A 5m8nC-3ixwA:
6.8		 5m8nC-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 9 HIS A 174
HIS A 321
ASN A 322
HIS A 325
THR A 348
 None
 1.16A 5m8nD-3ixwA:
6.9		 5m8nD-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 9 HIS A 321
ASN A 322
HIS A 325
THR A 348
SER A 351
 None
 0.93A 5m8nD-3ixwA:
6.9		 5m8nD-3ixwA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 174
HIS A 321
ASN A 322
HIS A 325
 None
 0.92A 5m8rA-3ixwA:
6.8		 5m8rA-3ixwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 7 HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.73A 5m8rA-3ixwA:
6.8		 5m8rA-3ixwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 8 HIS A 174
HIS A 321
ASN A 322
HIS A 325
 None
 0.89A 5m8rB-3ixwA:
6.7		 5m8rB-3ixwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 8 HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.76A 5m8rB-3ixwA:
6.7		 5m8rB-3ixwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 8 HIS A 174
HIS A 321
ASN A 322
HIS A 325
 None
 0.92A 5m8rD-3ixwA:
6.7		 5m8rD-3ixwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 8 HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.75A 5m8rD-3ixwA:
6.7		 5m8rD-3ixwA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_B_ACTB302_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 5 GLU A 162
TYR A 233
TYR A 155
ARG A 161
 None
 1.40A 5mthA-3ixwA:
3.4
5mthB-3ixwA:
2.9		 5mthA-3ixwA:
16.69
5mthB-3ixwA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MTH_H_ACTH304_0
(ANTIBODY FAB HEAVY
CHAIN
ANTIBODY FAB LIGHT
CHAIN)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 5 GLU A 162
TYR A 233
TYR A 155
ARG A 161
 None
 1.39A 5mthH-3ixwA:
1.8
5mthL-3ixwA:
2.7		 5mthH-3ixwA:
16.69
5mthL-3ixwA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 6 HIS A 321
HIS A 325
HIS A 174
HIS A 170
 None
 0.92A 5ncdA-3ixwA:
undetectable
5ncdD-3ixwA:
undetectable		 5ncdA-3ixwA:
16.18
5ncdD-3ixwA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 6 HIS A 170
HIS A 321
HIS A 325
HIS A 174
 None
 0.93A 5nelB-3ixwA:
undetectable
5nelC-3ixwA:
undetectable		 5nelB-3ixwA:
16.18
5nelC-3ixwA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.70A 5z0gA-3ixwA:
8.5
5z0gB-3ixwA:
undetectable		 5z0gA-3ixwA:
11.09
5z0gB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.52A 5z0gA-3ixwA:
8.5
5z0gB-3ixwA:
undetectable		 5z0gA-3ixwA:
11.09
5z0gB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.73A 5z0hA-3ixwA:
8.3
5z0hB-3ixwA:
undetectable		 5z0hA-3ixwA:
11.09
5z0hB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.63A 5z0hA-3ixwA:
8.3
5z0hB-3ixwA:
undetectable		 5z0hA-3ixwA:
11.09
5z0hB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.58A 5z0iA-3ixwA:
8.4
5z0iB-3ixwA:
undetectable		 5z0iA-3ixwA:
11.09
5z0iB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.72A 5z0jA-3ixwA:
8.4
5z0jB-3ixwA:
undetectable		 5z0jA-3ixwA:
11.09
5z0jB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.56A 5z0jA-3ixwA:
8.4
5z0jB-3ixwA:
undetectable		 5z0jA-3ixwA:
11.09
5z0jB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.72A 5z0kA-3ixwA:
8.3
5z0kB-3ixwA:
undetectable		 5z0kA-3ixwA:
11.09
5z0kB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.58A 5z0kA-3ixwA:
8.3
5z0kB-3ixwA:
undetectable		 5z0kA-3ixwA:
11.09
5z0kB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.72A 5z0lA-3ixwA:
8.4
5z0lB-3ixwA:
undetectable		 5z0lA-3ixwA:
11.09
5z0lB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
VAL A 326
 None
 0.65A 5z0lA-3ixwA:
8.4
5z0lB-3ixwA:
undetectable		 5z0lA-3ixwA:
11.09
5z0lB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 11 HIS A 170
HIS A 321
ASN A 322
HIS A 325
SER A 351
 None
 0.79A 5z0mA-3ixwA:
8.3
5z0mB-3ixwA:
undetectable		 5z0mA-3ixwA:
10.89
5z0mB-3ixwA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_A_TRPA501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 10 ALA A  50
LEU A 258
ASP A 260
VAL A 326
GLY A 324
 None
 1.28A 5zbdA-3ixwA:
undetectable		 5zbdA-3ixwA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZBD_B_TRPB501_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		5 / 10 ALA A  50
LEU A 258
ASP A 260
VAL A 326
GLY A 324
 None
 1.30A 5zbdB-3ixwA:
undetectable		 5zbdB-3ixwA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 5 HIS A 321
HIS A 325
PHE A 357
HIS A 361
 None
 0.86A 5zrdB-3ixwA:
6.8		 5zrdB-3ixwA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3ixw HEMOCYANIN AA6 CHAIN
(Androctonus
australis) 		4 / 6 HIS A 321
ASP A 299
TRP A 360
HIS A 361
 None
 1.49A 6nmpA-3ixwA:
0.0
6nmpC-3ixwA:
undetectable		 6nmpA-3ixwA:
20.16
6nmpC-3ixwA:
16.67