SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iy0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 3iy0 FAB 14, HEAVY DOMAIN
FAB 14, LIGHT DOMAIN
(Mus
musculus) 		7 / 12 TYR L  36
GLN L  89
PHE L  98
ASN H  35
VAL H  37
ALA H  97
TRP H 110
 None
 0.68A 1h8sA-3iy0L:
22.4		 1h8sA-3iy0L:
72.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3iy0 FAB 14, HEAVY DOMAIN
FAB 14, LIGHT DOMAIN
(Mus
musculus;
Mus
musculus) 		3 / 3 GLN L  89
HIS L  91
ARG H  99
 None
 0.74A 1zlqA-3iy0L:
undetectable		 1zlqA-3iy0L:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3iy0 FAB 14, LIGHT DOMAIN
(Mus
musculus) 		3 / 3 PHE L  71
TYR L  92
LEU L  47
 None
 0.75A 3keeB-3iy0L:
undetectable		 3keeB-3iy0L:
18.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3iy0 FAB 14, HEAVY DOMAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 109
 None
 0.39A 4m7kH-3iy0H:
22.9		 4m7kH-3iy0H:
53.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3iy0 FAB 14, HEAVY DOMAIN
(Mus
musculus) 		5 / 9 VAL H  12
ALA H  13
GLY H  92
SER H  88
GLY H 119
 None
 1.38A 4mmfA-3iy0H:
undetectable		 4mmfA-3iy0H:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 3iy0 FAB 14, HEAVY DOMAIN
(Mus
musculus) 		5 / 9 VAL H  12
ALA H  13
GLY H  92
SER H  88
GLY H 119
 None
 1.37A 4mmfB-3iy0H:
undetectable		 4mmfB-3iy0H:
13.08