SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		5 / 12 THR F 158
VAL F  68
ASN F 445
PHE F 243
LEU F  73
 None
 1.30A 1wsvA-3iyjF:
undetectable		 1wsvA-3iyjF:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		5 / 12 THR F 158
VAL F  68
ASN F 445
PHE F 243
LEU F  73
 None
 1.30A 1wsvB-3iyjF:
undetectable		 1wsvB-3iyjF:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		3 / 3 SER F 453
TYR F  34
HIS F  35
 None
 0.74A 2r2vD-3iyjF:
undetectable		 2r2vD-3iyjF:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 7 GLY F 156
PHE F 327
PHE F 441
PHE F 443
 None
 1.15A 3ko0D-3iyjF:
undetectable
3ko0E-3iyjF:
undetectable		 3ko0D-3iyjF:
11.72
3ko0E-3iyjF:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 7 LEU F 389
LEU F 392
ASN F 317
ILE F 320
 None
 1.04A 3u5jA-3iyjF:
undetectable		 3u5jA-3iyjF:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 8 LEU F 328
VAL F  98
TYR F 308
LEU F 153
 None
 1.10A 3v81A-3iyjF:
undetectable		 3v81A-3iyjF:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 7 ILE F  99
LEU F 461
GLY F 462
PHE F 465
 None
 0.82A 4iqqA-3iyjF:
undetectable		 4iqqA-3iyjF:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 8 ILE F  99
LEU F 461
GLY F 462
PHE F 465
 None
 0.79A 4iqqD-3iyjF:
undetectable		 4iqqD-3iyjF:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		5 / 12 ILE F 373
LEU F 461
VAL F 476
ALA F 467
LEU F 466
 None
 1.19A 4m11C-3iyjF:
undetectable		 4m11C-3iyjF:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 5 PHE F 441
PHE F 443
LEU F 226
PRO F 228
 None
 1.45A 4o8zA-3iyjF:
undetectable		 4o8zA-3iyjF:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 8 LEU F 328
VAL F  98
TYR F 308
LEU F 153
 None
 1.04A 4puoC-3iyjF:
undetectable		 4puoC-3iyjF:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		3 / 3 ASN F 317
SER F  23
ARG F  29
 None
 0.94A 5b2qA-3iyjF:
undetectable		 5b2qA-3iyjF:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		5 / 11 PRO F  76
LEU F  73
VAL F  98
TYR F  34
LEU F 452
 None
 1.47A 5hbmA-3iyjF:
undetectable		 5hbmA-3iyjF:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 8 GLN F 151
ASN F  64
ALA F  63
GLN F  65
 None
 1.14A 5km8A-3iyjF:
undetectable
5km8B-3iyjF:
undetectable		 5km8A-3iyjF:
16.26
5km8B-3iyjF:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		5 / 12 THR F 114
GLY F 144
ILE F 220
GLN F 221
LEU F 216
 None
 0.95A 5l0zA-3iyjF:
undetectable		 5l0zA-3iyjF:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 7 ILE F  99
LEU F 461
GLY F 462
PHE F 465
 None
 0.84A 5nooB-3iyjF:
undetectable		 5nooB-3iyjF:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		3 / 3 HIS F  87
SER F 378
LYS F  30
 None
 1.21A 5os7A-3iyjF:
undetectable		 5os7A-3iyjF:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		5 / 12 MET F 196
ASN F 333
ASP F 219
ILE F 220
PRO F 217
 None
 1.19A 6b3bA-3iyjF:
undetectable		 6b3bA-3iyjF:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		4 / 6 ARG F 259
ILE F 209
ASN F 210
ASP F 215
 None
 1.21A 6dhbA-3iyjF:
undetectable		 6dhbA-3iyjF:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3iyj MAJOR CAPSID PROTEIN
L1
(Deltapapillomavi
rus
4) 		3 / 3 HIS F  87
SER F 378
LYS F  30
 None
 1.21A 6gmdB-3iyjF:
undetectable		 6gmdB-3iyjF:
20.04