SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR
(Homo
sapiens) 		4 / 8 ILE F 142
TRP F 181
SER F 182
LEU F 185
 None
 1.00A 2cdqA-3iypF:
undetectable		 2cdqA-3iypF:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR
(Homo
sapiens) 		4 / 8 TRP F 119
THR F  70
TYR F  81
TYR F  95
 None
 1.49A 3wipB-3iypF:
undetectable
3wipC-3iypF:
undetectable		 3wipB-3iypF:
21.09
3wipC-3iypF:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR
(Homo
sapiens) 		4 / 7 ASP F 143
GLY F 147
SER F 155
PHE F 156
 None
 1.01A 4ac9C-3iypF:
undetectable		 4ac9C-3iypF:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR
(Homo
sapiens) 		4 / 4 LEU F 164
GLY F 166
SER F 167
SER F 169
 None
 1.35A 5uunB-3iypF:
undetectable		 5uunB-3iypF:
18.30