SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_G_AG2G7003_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 LEU B1061
LEU B 251
GLY B 250
ILE B 219
 None
 0.89A 1mt1G-3iz3B:
undetectable
1mt1J-3iz3B:
undetectable		 1mt1G-3iz3B:
3.39
1mt1J-3iz3B:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 7 ILE B 219
LEU B1061
LEU B 251
GLY B 250
 None
 0.89A 1mt1H-3iz3B:
undetectable
1mt1K-3iz3B:
undetectable		 1mt1H-3iz3B:
6.67
1mt1K-3iz3B:
3.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 8 LEU B1061
LEU B 251
GLY B 250
ILE B 219
 None
 0.88A 1n13A-3iz3B:
undetectable
1n13F-3iz3B:
undetectable		 1n13A-3iz3B:
3.39
1n13F-3iz3B:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 LEU B 537
ALA B 556
LEU B 588
THR B 557
 None
 1.32A 1tyrA-3iz3B:
undetectable		 1tyrA-3iz3B:
7.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 5 PHE D 179
LEU D 252
PHE D  31
MET D 226
 None
 1.15A 1wrkB-3iz3D:
undetectable		 1wrkB-3iz3D:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 ILE B 979
ILE B 820
ALA B 982
LEU B 967
PHE B 819
 None
 0.99A 1xzxX-3iz3B:
undetectable		 1xzxX-3iz3B:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 ILE B 979
ILE B 820
ALA B 982
LEU B 974
PHE B 819
 None
 1.12A 1xzxX-3iz3B:
undetectable		 1xzxX-3iz3B:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 ASN B 715
ILE B 409
MET B 413
 None
 0.69A 2h42C-3iz3B:
undetectable		 2h42C-3iz3B:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 ILE B 979
ILE B 820
ALA B 982
LEU B 967
PHE B 819
 None
 0.97A 2h79A-3iz3B:
undetectable		 2h79A-3iz3B:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 GLU B1264
ASP B 351
LEU B 208
SER B1241
ILE B1296
 None
 1.32A 2ogyA-3iz3B:
undetectable		 2ogyA-3iz3B:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 LEU B 251
LEU B 252
VAL B 258
LEU B1061
THR B1063
 None
 1.45A 2q7kA-3iz3B:
undetectable		 2q7kA-3iz3B:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_K_AG2K671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 8 ILE B 219
LEU B1061
LEU B 251
GLY B 250
 None
 0.89A 2qqcH-3iz3B:
undetectable
2qqcK-3iz3B:
undetectable		 2qqcH-3iz3B:
7.25
2qqcK-3iz3B:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 8 ILE B 219
LEU B1061
LEU B 251
GLY B 250
 None
 0.90A 2qqdB-3iz3B:
undetectable
2qqdC-3iz3B:
undetectable		 2qqdB-3iz3B:
7.25
2qqdC-3iz3B:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 3iz3 STRUCTURAL PROTEIN
VP1
VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1;
Cypovirus
1) 		5 / 12 LEU D 205
LEU D 202
LEU D 199
ARG B1272
MET D 227
 None
 1.28A 2w8yB-3iz3D:
undetectable		 2w8yB-3iz3D:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 9 PHE B 585
VAL B 492
GLY B 530
GLU B 524
ILE B 528
 None
 1.44A 2w98A-3iz3B:
undetectable		 2w98A-3iz3B:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 PRO B 192
ILE B 189
ASN B 349
LEU B 327
 None
 1.37A 2wekB-3iz3B:
undetectable		 2wekB-3iz3B:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_B_ADNB1302_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 6 GLU D 209
ALA D 125
ASN D 129
ALA D 126
 None
 1.14A 2zgwB-3iz3D:
undetectable		 2zgwB-3iz3D:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 6 TRP D 182
ASN D  25
ALA D  26
ASP D  22
 None
 1.34A 3aruA-3iz3D:
undetectable		 3aruA-3iz3D:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 3iz3 STRUCTURAL PROTEIN
VP1
VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 LEU D 205
LEU D 202
LEU D 199
ARG B1272
MET D 227
 None
 1.33A 3d90A-3iz3D:
undetectable		 3d90A-3iz3D:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 ILE B 979
ILE B 820
ALA B 982
LEU B 967
PHE B 819
 None
 0.89A 3gwsX-3iz3B:
undetectable		 3gwsX-3iz3B:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 ILE B 979
ILE B 820
ALA B 982
LEU B 974
PHE B 819
 None
 1.06A 3gwsX-3iz3B:
undetectable		 3gwsX-3iz3B:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 LEU D  35
LEU D  32
GLN D  30
LEU D 189
ASP D 192
 None
 1.28A 3gwuA-3iz3D:
undetectable		 3gwuA-3iz3D:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 VAL B 964
SER B 961
LEU B1059
 None
 0.71A 3n8xA-3iz3B:
undetectable		 3n8xA-3iz3B:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 GLN B 690
THR B 689
LEU B 453
 None
 0.72A 3ondA-3iz3B:
undetectable		 3ondA-3iz3B:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 GLN B 690
THR B 689
LEU B 453
 None
 0.72A 3ondB-3iz3B:
undetectable		 3ondB-3iz3B:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		3 / 3 TYR D 112
ASP D 108
ASP D  70
 None
 0.78A 4a6eA-3iz3D:
undetectable		 4a6eA-3iz3D:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 7 ILE B 766
PHE B 691
TYR B 772
HIS B 701
 None
 0.84A 4a97A-3iz3B:
2.7		 4a97A-3iz3B:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 ILE B 766
PHE B 691
TYR B 772
HIS B 701
 None
 0.87A 4a97I-3iz3B:
2.5		 4a97I-3iz3B:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 ARG B1021
ARG B1020
ILE B1035
 None
 0.91A 4b7qA-3iz3B:
undetectable		 4b7qA-3iz3B:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 LEU B 362
LEU B 365
LEU B 401
ALA B 368
MET B1305
 None
 1.31A 4fn9B-3iz3B:
undetectable		 4fn9B-3iz3B:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 3iz3 STRUCTURAL PROTEIN
VP1
VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 LEU D 205
LEU D 202
LEU D 199
ALA D 200
ARG B1272
 None
 1.30A 4fn9B-3iz3D:
undetectable		 4fn9B-3iz3D:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 8 ASN B 821
ALA B 818
PRO B 816
LEU B1047
 None
 0.81A 4jjkA-3iz3B:
undetectable		 4jjkA-3iz3B:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 ILE B 820
PHE B 819
LEU B1059
LEU B 255
ILE B 823
 None
 1.01A 4km2B-3iz3B:
undetectable		 4km2B-3iz3B:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 8 ALA B1145
GLU B1143
ASP B1167
ILE B1141
ILE B1155
 None
 1.13A 4kttB-3iz3B:
undetectable		 4kttB-3iz3B:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 8 ALA B1145
GLU B1143
ASP B1167
ILE B1141
ILE B1155
 None
 1.08A 4kttD-3iz3B:
undetectable		 4kttD-3iz3B:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYS_B_VIBB501_1
(THIAMINE
PYRIDINYLASE I)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 11 ILE B1330
SER B 703
THR B 523
TYR B 637
TYR B 706
 None
 1.20A 4kysB-3iz3B:
undetectable		 4kysB-3iz3B:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 12 LEU B 702
LEU B 767
ILE B 766
ILE B 482
PRO B 636
 None
 0.92A 4odrA-3iz3B:
undetectable
4odrB-3iz3B:
undetectable		 4odrA-3iz3B:
6.57
4odrB-3iz3B:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 11 THR B 371
GLY B 395
ASP B 335
ARG B 338
THR B 342
 None
 1.40A 4xt7A-3iz3B:
undetectable		 4xt7A-3iz3B:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 7 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.85A 4zdzA-3iz3D:
0.5		 4zdzA-3iz3D:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 7 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.77A 4ze3A-3iz3D:
undetectable		 4ze3A-3iz3D:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 8 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.82A 5esfA-3iz3D:
undetectable		 5esfA-3iz3D:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 8 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.73A 5esjA-3iz3D:
0.5		 5esjA-3iz3D:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 7 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.87A 5esmA-3iz3D:
undetectable		 5esmA-3iz3D:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EUM_B_ACTB603_0
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 4 ALA B 619
ASN B 711
ARG B 626
ILE B 620
 None
 1.30A 5eumB-3iz3B:
0.0		 5eumB-3iz3B:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 5 GLY B 200
PRO B1213
GLN B 173
THR B 175
 None
 1.26A 5h5fA-3iz3B:
undetectable		 5h5fA-3iz3B:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 ASP B1167
HIS B1169
ILE B1171
TYR B1173
 None
 1.28A 5ih0A-3iz3B:
undetectable		 5ih0A-3iz3B:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		5 / 11 ASP B 870
SER B 886
SER B 878
VAL B 918
TYR B 897
 None
 1.50A 5iqdD-3iz3B:
1.3		 5iqdD-3iz3B:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 THR B 608
HIS B 724
ASN B 723
 None
 0.97A 5n4tA-3iz3B:
undetectable		 5n4tA-3iz3B:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 8 GLU B1143
ASP B1167
ILE B1141
ILE B1155
 None
 0.91A 5t8sA-3iz3B:
undetectable		 5t8sA-3iz3B:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		3 / 3 LEU B 767
ILE B 694
TYR B 637
 None
 0.63A 5uunB-3iz3B:
undetectable		 5uunB-3iz3B:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 ILE B 314
ILE B 206
PHE B 197
PHE B 353
 None
 1.03A 5vkqC-3iz3B:
undetectable
5vkqD-3iz3B:
undetectable		 5vkqC-3iz3B:
21.93
5vkqD-3iz3B:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 6 PHE B 353
ILE B 314
ILE B 206
PHE B 197
 None
 1.02A 5vkqA-3iz3B:
undetectable
5vkqD-3iz3B:
undetectable		 5vkqA-3iz3B:
21.93
5vkqD-3iz3B:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 4 TYR B 835
ARG B 833
MET B 849
THR B 850
 None
 1.48A 5w97j-3iz3B:
0.0		 5w97j-3iz3B:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 PHE D  90
ALA D  71
ALA D 237
ALA D 263
THR D 268
 None
 1.33A 6aycA-3iz3D:
undetectable		 6aycA-3iz3D:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 3iz3 STRUCTURAL PROTEIN
VP1
VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1;
Cypovirus
1) 		5 / 12 GLY D  88
VAL B 337
LEU D  56
GLY D 138
SER D  91
 None
 1.08A 6c2mA-3iz3D:
undetectable		 6c2mA-3iz3D:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3iz3 STRUCTURAL PROTEIN
VP1
VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 6 LEU D  35
LEU D 189
ARG B1053
ARG D 265
 None
 1.01A 6ew0G-3iz3D:
undetectable		 6ew0G-3iz3D:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3iz3 STRUCTURAL PROTEIN
VP1
(Cypovirus
1) 		4 / 7 GLU B1143
ASP B1167
ILE B1141
ILE B1155
 None
 0.92A 6fbnA-3iz3B:
undetectable		 6fbnA-3iz3B:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 8 ASP D 222
TRP D 290
ARG D 225
ASN D 291
 None
 1.15A 6hisA-3iz3D:
undetectable
6hisB-3iz3D:
undetectable		 6hisA-3iz3D:
13.80
6hisB-3iz3D:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3iz3 VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 8 ASP D 222
TRP D 290
ARG D 225
ASN D 291
 None
 1.15A 6hisD-3iz3D:
undetectable
6hisE-3iz3D:
undetectable		 6hisD-3iz3D:
13.80
6hisE-3iz3D:
13.80