SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3iz4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3iz4 SSRA-BINDING PROTEIN
(Escherichia
coli) 		5 / 10 ALA B  46
LEU B  79
LEU B 117
LEU B  89
PHE B  48
 None
 1.06A 3fl9E-3iz4B:
undetectable		 3fl9E-3iz4B:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3iz4 SSRA-BINDING PROTEIN
(Escherichia
coli) 		4 / 8 LEU B  53
VAL B 115
TYR B  20
LEU B  86
 None
 0.98A 3v81A-3iz4B:
undetectable		 3v81A-3iz4B:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3iz4 SSRA-BINDING PROTEIN
(Escherichia
coli) 		4 / 8 LEU B  53
VAL B 115
TYR B  20
LEU B  86
 None
 1.01A 3v81C-3iz4B:
undetectable		 3v81C-3iz4B:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3iz4 SSRA-BINDING PROTEIN
(Escherichia
coli) 		4 / 8 LEU B  53
VAL B 115
TYR B  20
LEU B  86
 None
 1.01A 4pwdC-3iz4B:
undetectable		 4pwdC-3iz4B:
13.42