SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3izq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU 1 508
LEU 1 510
LEU 1 580
CYH 1 505
THR 1 610
 None
 1.24A 1a28A-3izq1:
undetectable		 1a28A-3izq1:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 LEU 1 508
LEU 1 510
LEU 1 580
CYH 1 505
THR 1 610
 None
 1.16A 1a28B-3izq1:
undetectable		 1a28B-3izq1:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 PHE 1 403
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 1.18A 1hvyA-3izq1:
undetectable		 1hvyA-3izq1:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 11 PHE 1 403
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 1.16A 1hvyC-3izq1:
undetectable		 1hvyC-3izq1:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 9 PHE 1 403
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 1.26A 1i00A-3izq1:
undetectable		 1i00A-3izq1:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 ASP 1  66
GLU 1  68
LEU 1  74
LEU 1  71
 None
 1.13A 1np1A-3izq1:
undetectable		 1np1A-3izq1:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.37A 1v54A-3izq1:
undetectable
1v54C-3izq1:
undetectable		 1v54A-3izq1:
20.06
1v54C-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.39A 1v54N-3izq1:
undetectable
1v54P-3izq1:
undetectable		 1v54N-3izq1:
20.06
1v54P-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.35A 1v55A-3izq1:
undetectable
1v55C-3izq1:
undetectable		 1v55A-3izq1:
20.06
1v55C-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.37A 2dyrA-3izq1:
undetectable
2dyrC-3izq1:
undetectable		 2dyrA-3izq1:
20.06
2dyrC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.39A 2dyrN-3izq1:
undetectable
2dyrP-3izq1:
undetectable		 2dyrN-3izq1:
20.06
2dyrP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.36A 2dysA-3izq1:
undetectable
2dysC-3izq1:
undetectable		 2dysA-3izq1:
20.06
2dysC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.32A 2dysN-3izq1:
undetectable
2dysP-3izq1:
undetectable		 2dysN-3izq1:
20.06
2dysP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.35A 2eijA-3izq1:
undetectable
2eijC-3izq1:
undetectable		 2eijA-3izq1:
20.06
2eijC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.37A 2eijN-3izq1:
undetectable
2eijP-3izq1:
undetectable		 2eijN-3izq1:
20.06
2eijP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.38A 2eikN-3izq1:
undetectable
2eikP-3izq1:
undetectable		 2eikN-3izq1:
20.06
2eikP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.38A 2eilN-3izq1:
undetectable
2eilP-3izq1:
undetectable		 2eilN-3izq1:
20.06
2eilP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.30A 2eimA-3izq1:
undetectable
2eimC-3izq1:
undetectable		 2eimA-3izq1:
20.06
2eimC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.32A 2einA-3izq1:
undetectable
2einC-3izq1:
undetectable		 2einA-3izq1:
20.06
2einC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.35A 2einN-3izq1:
undetectable
2einP-3izq1:
undetectable		 2einN-3izq1:
20.06
2einP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 10 PHE 1 403
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 1.27A 2tsrC-3izq1:
undetectable		 2tsrC-3izq1:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		3 / 3 ARG 1 540
ARG 1 537
PRO 1 521
 None
 0.92A 2wljA-3izq1:
undetectable		 2wljA-3izq1:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.38A 2y69A-3izq1:
undetectable
2y69C-3izq1:
undetectable		 2y69A-3izq1:
20.06
2y69C-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.39A 2zxwA-3izq1:
undetectable
2zxwC-3izq1:
undetectable		 2zxwA-3izq1:
20.06
2zxwC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.36A 2zxwN-3izq1:
undetectable
2zxwP-3izq1:
undetectable		 2zxwN-3izq1:
20.06
2zxwP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.33A 3abmN-3izq1:
undetectable
3abmP-3izq1:
undetectable		 3abmN-3izq1:
20.06
3abmP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.42A 3ag1N-3izq1:
undetectable
3ag1P-3izq1:
undetectable		 3ag1N-3izq1:
20.06
3ag1P-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.41A 3ag2A-3izq1:
undetectable
3ag2C-3izq1:
undetectable		 3ag2A-3izq1:
20.06
3ag2C-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.39A 3ag2N-3izq1:
2.6
3ag2P-3izq1:
undetectable		 3ag2N-3izq1:
20.06
3ag2P-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.38A 3ag3N-3izq1:
undetectable
3ag3P-3izq1:
undetectable		 3ag3N-3izq1:
20.06
3ag3P-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.37A 3ag4A-3izq1:
undetectable
3ag4C-3izq1:
undetectable		 3ag4A-3izq1:
20.06
3ag4C-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.36A 3ag4N-3izq1:
undetectable
3ag4P-3izq1:
undetectable		 3ag4N-3izq1:
20.06
3ag4P-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.36A 3asnA-3izq1:
undetectable
3asnC-3izq1:
undetectable		 3asnA-3izq1:
20.06
3asnC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ALA 1 492
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 0.97A 3k2hA-3izq1:
undetectable		 3k2hA-3izq1:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ALA 1 492
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 0.95A 3k2hB-3izq1:
undetectable		 3k2hB-3izq1:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ALA 1 492
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 0.94A 3nrrA-3izq1:
undetectable		 3nrrA-3izq1:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ALA 1 492
GLU 1 434
ILE 1 430
GLY 1 428
PHE 1 401
 None
 0.96A 3nrrB-3izq1:
undetectable		 3nrrB-3izq1:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 GLN 1 268
GLY 1 304
LEU 1 299
MET 1 297
ALA 1 272
 None
 1.07A 3sxjA-3izq1:
undetectable		 3sxjA-3izq1:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 GLN 1 268
GLY 1 304
LEU 1 299
MET 1 297
ALA 1 272
 None
 1.08A 3sxjB-3izq1:
undetectable		 3sxjB-3izq1:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 8 PHE 1 170
ALA 1 384
PHE 1 240
ALA 1 245
 None
 0.96A 3t3sF-3izq1:
undetectable		 3t3sF-3izq1:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ILE 1 578
GLY 1 489
ASP 1 490
ILE 1 500
LEU 1 589
 None
 1.02A 4a81A-3izq1:
undetectable		 4a81A-3izq1:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 LEU 1 476
ARG 1 588
PRO 1 440
SER 1 441
 None
 1.33A 4kmmB-3izq1:
3.8		 4kmmB-3izq1:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 GLY 1 489
GLY 1 530
ILE 1 266
ASN 1 261
SER 1 267
 None
 1.05A 4rtsA-3izq1:
undetectable		 4rtsA-3izq1:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 CYH 1 236
ILE 1 235
GLN 1 455
ILE 1 266
 None
 1.15A 4z4dA-3izq1:
2.6		 4z4dA-3izq1:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 4 ARG 1 564
HIS 1 584
ALA 1 583
GLU 1 509
 None
 1.41A 5a06A-3izq1:
4.2
5a06F-3izq1:
4.2		 5a06A-3izq1:
19.37
5a06F-3izq1:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.38A 5b1aN-3izq1:
undetectable
5b1aP-3izq1:
undetectable		 5b1aN-3izq1:
20.06
5b1aP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.36A 5b1bN-3izq1:
undetectable
5b1bP-3izq1:
undetectable		 5b1bN-3izq1:
20.06
5b1bP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.40A 5b3sN-3izq1:
undetectable
5b3sP-3izq1:
undetectable		 5b3sN-3izq1:
20.06
5b3sP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_A_ACTA202_0
(NITROGEN REGULATORY
PROTEIN P-II)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 4 VAL 1 531
GLY 1 530
ARG 1 588
VAL 1 405
 None
 1.23A 5d4nA-3izq1:
undetectable
5d4nB-3izq1:
undetectable		 5d4nA-3izq1:
11.78
5d4nB-3izq1:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 GLY 1 590
ILE 1 606
ILE 1 526
ARG 1 595
ALA 1 536
 None
 1.02A 5e72A-3izq1:
3.1		 5e72A-3izq1:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.39A 5iy5A-3izq1:
undetectable
5iy5C-3izq1:
undetectable		 5iy5A-3izq1:
20.06
5iy5C-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 5 ILE 1 351
LYS 1 329
ILE 1 328
VAL 1 276
 None
 1.01A 5jmnA-3izq1:
undetectable		 5jmnA-3izq1:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 LEU 1 436
SER 1 435
ILE 1 430
PHE 1 401
 None
 1.01A 5jw1A-3izq1:
undetectable		 5jw1A-3izq1:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ILE 1 305
GLY 1 304
SER 1 301
ALA 1 300
ALA 1 272
 None
 1.00A 5n0oB-3izq1:
1.9		 5n0oB-3izq1:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 GLY 1 428
ARG 1 588
ASP 1 399
ASN 1 586
 None
 1.06A 5n5dB-3izq1:
undetectable		 5n5dB-3izq1:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 9 ALA 1 178
ASP 1 177
VAL 1 172
HIS 1 296
ILE 1 273
 None
 1.21A 5om2A-3izq1:
undetectable
5om2B-3izq1:
undetectable		 5om2A-3izq1:
10.17
5om2B-3izq1:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.40A 5x19N-3izq1:
undetectable
5x19P-3izq1:
undetectable		 5x19N-3izq1:
20.06
5x19P-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.41A 5x1bN-3izq1:
undetectable
5x1bP-3izq1:
undetectable		 5x1bN-3izq1:
20.06
5x1bP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.46A 5x1fN-3izq1:
undetectable
5x1fP-3izq1:
undetectable		 5x1fN-3izq1:
20.06
5x1fP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.37A 5zcqN-3izq1:
undetectable
5zcqP-3izq1:
undetectable		 5zcqN-3izq1:
20.06
5zcqP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 12 ILE 1 609
VAL 1 474
LEU 1 436
PHE 1 401
LEU 1 425
 None
 1.35A 6a7pB-3izq1:
0.4		 6a7pB-3izq1:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 PHE 1 401
VAL 1 474
LEU 1 478
LEU 1 436
 None
 1.01A 6e43D-3izq1:
undetectable		 6e43D-3izq1:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		5 / 10 ARG 1 256
VAL 1 259
ALA 1 252
LEU 1 298
LEU 1 299
 None
 0.88A 6f6nA-3izq1:
undetectable
6f6nB-3izq1:
undetectable		 6f6nA-3izq1:
7.61
6f6nB-3izq1:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.40A 6nknA-3izq1:
undetectable
6nknC-3izq1:
undetectable		 6nknA-3izq1:
20.06
6nknC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.47A 6nmfN-3izq1:
undetectable
6nmfP-3izq1:
undetectable		 6nmfN-3izq1:
20.06
6nmfP-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.39A 6nmpA-3izq1:
undetectable
6nmpC-3izq1:
undetectable		 6nmpA-3izq1:
20.06
6nmpC-3izq1:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3izq ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN
(Saccharomyces
cerevisiae) 		4 / 7 ASP 1 366
THR 1 365
TYR 1 364
HIS 1 243
 None
 1.40A 6nmpN-3izq1:
undetectable
6nmpP-3izq1:
undetectable		 6nmpN-3izq1:
20.06
6nmpP-3izq1:
15.65