SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3izy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 ALA P 440
VAL P 388
TRP P 393
None
0.70A 1c4dA-3izyP:
undetectable
1c4dB-3izyP:
undetectable
1c4dA-3izyP:
2.66
1c4dB-3izyP:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 TRP P 393
ALA P 440
VAL P 388
None
0.78A 1c4dA-3izyP:
undetectable
1c4dB-3izyP:
undetectable
1c4dA-3izyP:
2.66
1c4dB-3izyP:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 ALA P 440
VAL P 388
TRP P 393
None
0.67A 1c4dC-3izyP:
undetectable
1c4dD-3izyP:
undetectable
1c4dC-3izyP:
2.66
1c4dD-3izyP:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 TRP P 393
ALA P 440
VAL P 388
None
0.68A 1c4dC-3izyP:
undetectable
1c4dD-3izyP:
undetectable
1c4dC-3izyP:
2.66
1c4dD-3izyP:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD6_0
(GRAMICIDIN A)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 4 VAL P 434
TRP P 393
ALA P 394
VAL P 388
None
1.16A 1gmkC-3izyP:
undetectable
1gmkD-3izyP:
undetectable
1gmkC-3izyP:
2.66
1gmkD-3izyP:
2.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.11A 1v55C-3izyP:
undetectable
1v55N-3izyP:
undetectable
1v55P-3izyP:
undetectable
1v55C-3izyP:
18.22
1v55N-3izyP:
21.85
1v55P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
6 / 12 ASP P 423
GLY P 379
GLY P 420
ILE P 177
VAL P 182
ILE P 375
None
1.37A 2fxeA-3izyP:
undetectable
2fxeA-3izyP:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJ8_C_AZZC1211_1
(DEOXYNUCLEOSIDE
KINASE)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 12 VAL P 318
LEU P 257
MET P 186
GLN P 250
ALA P 279
None
1.39A 2jj8C-3izyP:
undetectable
2jj8C-3izyP:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 VAL P 388
GLU P 437
GLU P 435
None
0.74A 2nv4A-3izyP:
2.2
2nv4A-3izyP:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
6 / 12 GLN P 215
ILE P 376
LEU P 424
GLY P 404
ALA P 374
VAL P 359
None
1.20A 2oc8A-3izyP:
undetectable
2oc8A-3izyP:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 5 LEU P 200
VAL P 281
LEU P 345
ARG P 245
None
0.91A 2oiqA-3izyP:
undetectable
2oiqA-3izyP:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 ARG P 441
GLU P 442
GLN P 453
None
1.03A 2p16A-3izyP:
undetectable
2p16A-3izyP:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.12A 3ablA-3izyP:
undetectable
3ablC-3izyP:
undetectable
3ablP-3izyP:
undetectable
3ablA-3izyP:
21.85
3ablC-3izyP:
18.22
3ablP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.11A 3ablC-3izyP:
undetectable
3ablN-3izyP:
undetectable
3ablP-3izyP:
undetectable
3ablC-3izyP:
18.22
3ablN-3izyP:
21.85
3ablP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.11A 3abmA-3izyP:
undetectable
3abmC-3izyP:
undetectable
3abmP-3izyP:
undetectable
3abmA-3izyP:
21.85
3abmC-3izyP:
18.22
3abmP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.16A 3asnC-3izyP:
undetectable
3asnN-3izyP:
undetectable
3asnP-3izyP:
undetectable
3asnC-3izyP:
18.22
3asnN-3izyP:
21.85
3asnP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.15A 3asoA-3izyP:
undetectable
3asoC-3izyP:
undetectable
3asoP-3izyP:
undetectable
3asoA-3izyP:
21.85
3asoC-3izyP:
18.22
3asoP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.15A 3asoC-3izyP:
undetectable
3asoN-3izyP:
undetectable
3asoP-3izyP:
undetectable
3asoC-3izyP:
18.22
3asoN-3izyP:
21.85
3asoP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 5 VAL P 444
GLN P 453
ARG P 382
ARG P 439
None
1.49A 3bjwE-3izyP:
undetectable
3bjwE-3izyP:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 ARG P 201
VAL P 323
THR P 231
None
0.75A 3ndtA-3izyP:
undetectable
3ndtA-3izyP:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 PRO P 351
THR P 380
ILE P 418
ASN P 403
None
0.95A 3p50A-3izyP:
undetectable
3p50A-3izyP:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 PRO P 351
THR P 380
ILE P 418
ASN P 403
None
0.96A 3p50B-3izyP:
undetectable
3p50B-3izyP:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 PRO P 351
THR P 380
ILE P 418
ASN P 403
None
0.96A 3p50C-3izyP:
undetectable
3p50C-3izyP:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 PRO P 351
THR P 380
ILE P 418
ASN P 403
None
0.96A 3p50D-3izyP:
undetectable
3p50D-3izyP:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 12 LEU P 334
ALA P 335
LEU P 224
ILE P 213
GLY P 212
None
0.92A 3q95B-3izyP:
undetectable
3q95B-3izyP:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.14A 3wg7A-3izyP:
undetectable
3wg7C-3izyP:
undetectable
3wg7P-3izyP:
undetectable
3wg7A-3izyP:
21.85
3wg7C-3izyP:
18.22
3wg7P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.13A 3wg7C-3izyP:
undetectable
3wg7N-3izyP:
undetectable
3wg7P-3izyP:
undetectable
3wg7C-3izyP:
18.22
3wg7N-3izyP:
21.85
3wg7P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.12A 3x2qA-3izyP:
undetectable
3x2qC-3izyP:
undetectable
3x2qP-3izyP:
undetectable
3x2qA-3izyP:
21.85
3x2qC-3izyP:
18.22
3x2qP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.11A 3x2qC-3izyP:
undetectable
3x2qN-3izyP:
undetectable
3x2qP-3izyP:
undetectable
3x2qC-3izyP:
18.22
3x2qN-3izyP:
21.85
3x2qP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 6 GLU P 713
ILE P 617
GLU P 545
VAL P 515
None
0.99A 4ejwB-3izyP:
undetectable
4ejwB-3izyP:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 ARG P 397
TYR P 411
ASN P 403
None
0.95A 4ffwB-3izyP:
undetectable
4ffwB-3izyP:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 11 LEU P 334
ALA P 335
LEU P 224
ILE P 213
GLY P 212
None
0.88A 4pxmB-3izyP:
undetectable
4pxmB-3izyP:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_C_MTXC201_1
(DIHYDROFOLATE
REDUCTASE)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 11 ILE P 185
ALA P 219
SER P 223
ILE P 230
LEU P 334
None
1.30A 4qi9C-3izyP:
undetectable
4qi9C-3izyP:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 11 GLY P 671
ILE P 653
LEU P 694
LEU P 676
ILE P 674
None
1.18A 4xumB-3izyP:
undetectable
4xumB-3izyP:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 9 TYR P 572
ILE P 519
GLY P 573
ILE P 571
ALA P 564
None
1.24A 4yp2B-3izyP:
undetectable
4yp2B-3izyP:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.15A 5b1aA-3izyP:
undetectable
5b1aC-3izyP:
undetectable
5b1aP-3izyP:
undetectable
5b1aA-3izyP:
21.85
5b1aC-3izyP:
18.22
5b1aP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.13A 5b1bA-3izyP:
undetectable
5b1bC-3izyP:
undetectable
5b1bP-3izyP:
undetectable
5b1bA-3izyP:
21.85
5b1bC-3izyP:
18.22
5b1bP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.17A 5b3sA-3izyP:
undetectable
5b3sC-3izyP:
undetectable
5b3sP-3izyP:
undetectable
5b3sA-3izyP:
21.85
5b3sC-3izyP:
18.22
5b3sP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
5 / 9 TYR P 572
ILE P 519
GLY P 573
ILE P 571
ALA P 564
None
1.24A 5cf9B-3izyP:
undetectable
5cf9B-3izyP:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.10A 5iy5C-3izyP:
undetectable
5iy5N-3izyP:
undetectable
5iy5P-3izyP:
undetectable
5iy5C-3izyP:
18.10
5iy5N-3izyP:
21.85
5iy5P-3izyP:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 VAL P 183
GLY P 192
LEU P 196
THR P 194
None
1.10A 5sxqB-3izyP:
undetectable
5sxqB-3izyP:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 6 ASN P 533
ALA P 530
VAL P 534
ASP P 278
None
1.14A 5umd2-3izyP:
undetectable
5umdF-3izyP:
undetectable
5umd2-3izyP:
9.76
5umdF-3izyP:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.07A 5w97A-3izyP:
undetectable
5w97C-3izyP:
undetectable
5w97c-3izyP:
undetectable
5w97A-3izyP:
21.85
5w97C-3izyP:
18.22
5w97c-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.08A 5w97C-3izyP:
undetectable
5w97a-3izyP:
undetectable
5w97c-3izyP:
undetectable
5w97C-3izyP:
18.22
5w97a-3izyP:
21.85
5w97c-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.10A 5wauA-3izyP:
undetectable
5wauC-3izyP:
undetectable
5wauc-3izyP:
undetectable
5wauA-3izyP:
21.85
5wauC-3izyP:
18.22
5wauc-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.08A 5wauC-3izyP:
undetectable
5waua-3izyP:
undetectable
5wauc-3izyP:
undetectable
5wauC-3izyP:
18.22
5waua-3izyP:
21.85
5wauc-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.10A 5x19A-3izyP:
undetectable
5x19C-3izyP:
undetectable
5x19P-3izyP:
undetectable
5x19A-3izyP:
21.85
5x19C-3izyP:
18.22
5x19P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.09A 5x1bA-3izyP:
undetectable
5x1bC-3izyP:
undetectable
5x1bP-3izyP:
undetectable
5x1bA-3izyP:
21.85
5x1bC-3izyP:
18.22
5x1bP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.07A 5x1fA-3izyP:
undetectable
5x1fC-3izyP:
undetectable
5x1fP-3izyP:
undetectable
5x1fA-3izyP:
21.85
5x1fC-3izyP:
18.22
5x1fP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.12A 5xdqA-3izyP:
undetectable
5xdqC-3izyP:
undetectable
5xdqP-3izyP:
undetectable
5xdqA-3izyP:
21.85
5xdqC-3izyP:
18.22
5xdqP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.10A 5xdqC-3izyP:
undetectable
5xdqN-3izyP:
undetectable
5xdqP-3izyP:
undetectable
5xdqC-3izyP:
18.22
5xdqN-3izyP:
21.85
5xdqP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.11A 5xdxC-3izyP:
undetectable
5xdxN-3izyP:
undetectable
5xdxP-3izyP:
undetectable
5xdxC-3izyP:
17.74
5xdxN-3izyP:
21.85
5xdxP-3izyP:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.14A 5z84A-3izyP:
undetectable
5z84C-3izyP:
undetectable
5z84P-3izyP:
undetectable
5z84A-3izyP:
21.85
5z84C-3izyP:
18.22
5z84P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.14A 5z84C-3izyP:
undetectable
5z84N-3izyP:
undetectable
5z84P-3izyP:
undetectable
5z84C-3izyP:
18.22
5z84N-3izyP:
21.85
5z84P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.14A 5z85C-3izyP:
undetectable
5z85N-3izyP:
undetectable
5z85P-3izyP:
undetectable
5z85C-3izyP:
18.22
5z85N-3izyP:
21.85
5z85P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.13A 5z86A-3izyP:
undetectable
5z86C-3izyP:
undetectable
5z86P-3izyP:
undetectable
5z86A-3izyP:
21.85
5z86C-3izyP:
18.22
5z86P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.14A 5z86C-3izyP:
undetectable
5z86N-3izyP:
undetectable
5z86P-3izyP:
undetectable
5z86C-3izyP:
18.22
5z86N-3izyP:
21.85
5z86P-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.14A 5zcoA-3izyP:
undetectable
5zcoC-3izyP:
undetectable
5zcoP-3izyP:
undetectable
5zcoA-3izyP:
21.85
5zcoC-3izyP:
18.22
5zcoP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.15A 5zcoC-3izyP:
undetectable
5zcoN-3izyP:
undetectable
5zcoP-3izyP:
undetectable
5zcoC-3izyP:
18.22
5zcoN-3izyP:
21.85
5zcoP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.15A 5zcpA-3izyP:
undetectable
5zcpC-3izyP:
undetectable
5zcpP-3izyP:
undetectable
5zcpA-3izyP:
21.85
5zcpC-3izyP:
18.22
5zcpP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.15A 5zcpC-3izyP:
undetectable
5zcpN-3izyP:
undetectable
5zcpP-3izyP:
undetectable
5zcpC-3izyP:
18.22
5zcpN-3izyP:
21.85
5zcpP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.16A 5zcqA-3izyP:
undetectable
5zcqC-3izyP:
undetectable
5zcqP-3izyP:
undetectable
5zcqA-3izyP:
21.85
5zcqC-3izyP:
18.22
5zcqP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
3 / 3 GLU P 543
LEU P 614
ARG P 613
None
0.71A 6d8fA-3izyP:
undetectable
6d8fA-3izyP:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_ACTA405_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 6 THR P 252
PRO P 181
ARG P 179
ILE P 375
None
1.27A 6ef6A-3izyP:
undetectable
6ef6A-3izyP:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 5 GLN P 215
THR P 214
THR P 252
GLY P 218
None
1.22A 6gbnC-3izyP:
undetectable
6gbnC-3izyP:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 8 LEU P 326
HIS P 238
ASP P 198
THR P 194
None
1.07A 6nknC-3izyP:
undetectable
6nknN-3izyP:
undetectable
6nknP-3izyP:
undetectable
6nknC-3izyP:
18.22
6nknN-3izyP:
21.85
6nknP-3izyP:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3izy TRANSLATION
INITIATION FACTOR
IF-2, MITOCHONDRIAL

(Bos
taurus)
4 / 7 HIS P 238
ASP P 198
THR P 194
LEU P 326
None
1.08A 6nmfA-3izyP:
undetectable
6nmfC-3izyP:
undetectable
6nmfP-3izyP:
undetectable
6nmfA-3izyP:
21.85
6nmfC-3izyP:
18.22
6nmfP-3izyP:
18.22