SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))
3j04 MYOSIN-11
(Gallus
gallus)
4 / 7 VAL A 387
LEU A 613
VAL A 621
LEU A 362
None
0.73A 1cqpA-3j04A:
undetectable
1cqpB-3j04A:
undetectable
1cqpA-3j04A:
11.10
1cqpB-3j04A:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 5 THR A 673
GLU A 268
THR A 269
LEU A 464
None
1.30A 1d4fC-3j04A:
undetectable
1d4fC-3j04A:
17.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)
3j04 MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus
gallus)
4 / 8 MET C  35
GLN C  40
PRO C  42
GLU C  46
None
1.09A 1dtlA-3j04C:
6.2
1dtlA-3j04C:
33.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 11 LEU A 613
VAL A 609
ILE A 427
VAL A 387
MET A 391
None
1.25A 1gx9A-3j04A:
undetectable
1gx9A-3j04A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 11 LEU A 271
ALA A 467
LEU A 667
GLN A 666
ARG A 440
None
1.30A 1iiuA-3j04A:
undetectable
1iiuA-3j04A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus
gallus;
Gallus
gallus)
3 / 3 ARG A 731
ASP C  96
ASN C 139
None
0.90A 1nbhA-3j04A:
undetectable
1nbhA-3j04A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus
gallus;
Gallus
gallus)
3 / 3 ARG A 731
ASP C  96
ASN C 139
None
0.90A 1nbhD-3j04A:
undetectable
1nbhD-3j04A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)
3j04 MYOSIN REGULATORY
LIGHT CHAIN 2,
SMOOTH MUSCLE MAJOR
ISOFORM

(Gallus
gallus)
4 / 5 LEU B 126
VAL B 138
TYR B 142
THR B 127
None
1.36A 1nw3A-3j04B:
undetectable
1nw3A-3j04B:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 6 LEU A 541
TRP A 597
LEU A 480
PHE A 581
None
1.45A 1ru9H-3j04A:
undetectable
1ru9L-3j04A:
undetectable
1ru9H-3j04A:
13.10
1ru9L-3j04A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 6 LEU A 541
TRP A 597
LEU A 480
PHE A 581
None
1.50A 1rukH-3j04A:
undetectable
1rukL-3j04A:
undetectable
1rukH-3j04A:
13.10
1rukL-3j04A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)
3j04 MYOSIN REGULATORY
LIGHT CHAIN 2,
SMOOTH MUSCLE MAJOR
ISOFORM

(Gallus
gallus)
4 / 4 LEU B 126
THR B 127
ILE B 117
HIS B 121
None
1.40A 2jfaB-3j04B:
undetectable
2jfaB-3j04B:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 GLY A 462
ASN A 680
VAL A 682
ILE A 156
ILE A 191
None
0.88A 2qakB-3j04A:
undetectable
2qakB-3j04A:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 LEU A 670
SER A 179
TYR A 586
ASN A 483
ALA A 467
None
1.47A 2vdmA-3j04A:
undetectable
2vdmB-3j04A:
undetectable
2vdmA-3j04A:
18.72
2vdmB-3j04A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_B_EV1B1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 8 LEU A 362
PHE A 367
MET A 378
PHE A 398
None
0.77A 2weyB-3j04A:
undetectable
2weyB-3j04A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)
3j04 MYOSIN REGULATORY
LIGHT CHAIN 2,
SMOOTH MUSCLE MAJOR
ISOFORM

(Gallus
gallus)
3 / 3 ASP B  26
PHE B  25
LEU B  93
None
0.69A 2zi9A-3j04B:
undetectable
2zi9A-3j04B:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)
3j04 MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus
gallus)
4 / 4 LEU C  70
GLN C   7
THR C   8
THR C  75
None
1.49A 2zj0D-3j04C:
undetectable
2zj0D-3j04C:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)
3j04 MYOSIN-11
(Gallus
gallus)
3 / 3 MET A 342
GLU A 348
ASP A 623
None
0.77A 3a25A-3j04A:
undetectable
3a25A-3j04A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)
3j04 MYOSIN-11
(Gallus
gallus)
3 / 3 TYR A 127
TYR A 108
ILE A 124
None
0.78A 3eteA-3j04A:
0.9
3eteB-3j04A:
undetectable
3eteA-3j04A:
20.41
3eteB-3j04A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)
3j04 MYOSIN-11
MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus
gallus;
Gallus
gallus)
3 / 3 ASP C  33
ARG A 804
ALA A 808
None
0.75A 3mbgC-3j04C:
undetectable
3mbgC-3j04C:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 7 LEU A 705
GLN A 490
PHE A 493
LEU A 519
None
0.93A 3qeoB-3j04A:
undetectable
3qeoB-3j04A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 5 LEU A 307
GLY A 309
PHE A 290
ASN A 364
None
1.29A 3uq6B-3j04A:
undetectable
3uq6B-3j04A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)
3j04 MYOSIN-11
(Gallus
gallus)
3 / 3 ASP A 618
ARG A 354
ASP A 623
None
0.80A 4fp9F-3j04A:
undetectable
4fp9F-3j04A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 7 VAL A 123
ILE A 153
ILE A 156
ALA A 155
None
0.95A 4lv9B-3j04A:
undetectable
4lv9B-3j04A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 LEU A 450
ALA A 227
ILE A 254
ALA A 265
ILE A 463
None
0.96A 4o2bD-3j04A:
undetectable
4o2bD-3j04A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)
3j04 MYOSIN-11
(Gallus
gallus)
3 / 3 LEU A 541
MET A 602
TYR A 663
None
0.97A 4p6xG-3j04A:
undetectable
4p6xG-3j04A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)
3j04 MYOSIN-11
(Gallus
gallus)
3 / 3 ARG A 733
GLU A 786
TYR A 734
None
0.90A 4r29D-3j04A:
undetectable
4r29D-3j04A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)
3j04 MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus
gallus)
3 / 3 MET C 119
GLU C 123
LEU C 127
None
0.66A 4v2oB-3j04C:
undetectable
4v2oB-3j04C:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 7 ASP A 465
ILE A 466
GLY A 177
THR A 184
None
1.18A 4zxiA-3j04A:
undetectable
4zxiA-3j04A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 7 ASP A 465
ILE A 466
GLY A 468
THR A 184
None
1.00A 4zxiA-3j04A:
undetectable
4zxiA-3j04A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 5 LEU A 541
CYH A 545
LEU A 645
ASP A 552
None
1.10A 5mafA-3j04A:
undetectable
5mafA-3j04A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.04A 5n0oA-3j04A:
undetectable
5n0oA-3j04A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.04A 5n0oB-3j04A:
undetectable
5n0oB-3j04A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.05A 5n0rA-3j04A:
undetectable
5n0rA-3j04A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.07A 5n0sA-3j04A:
undetectable
5n0sA-3j04A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.05A 5n0tA-3j04A:
undetectable
5n0tA-3j04A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.05A 5n0tB-3j04A:
undetectable
5n0tB-3j04A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.06A 5n0wA-3j04A:
undetectable
5n0wA-3j04A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.06A 5n0wB-3j04A:
1.7
5n0wB-3j04A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.04A 5n0xA-3j04A:
undetectable
5n0xA-3j04A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.04A 5n0xB-3j04A:
undetectable
5n0xB-3j04A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 262
GLY A 264
PHE A 460
TYR A 161
ALA A 198
None
1.05A 5n4iA-3j04A:
undetectable
5n4iA-3j04A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 6 ARG A 437
THR A 610
ASP A 607
LEU A 605
None
0.80A 5tdzA-3j04A:
undetectable
5tdzA-3j04A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 6 ILE A 267
ILE A 289
PHE A 248
PHE A 332
None
0.98A 5vkqB-3j04A:
undetectable
5vkqC-3j04A:
3.0
5vkqB-3j04A:
20.13
5vkqC-3j04A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
3j04 MYOSIN-11
(Gallus
gallus)
4 / 6 ILE A 267
ILE A 289
PHE A 248
PHE A 332
None
1.00A 5vkqC-3j04A:
3.0
5vkqD-3j04A:
3.0
5vkqC-3j04A:
20.13
5vkqD-3j04A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)
3j04 MYOSIN-11
(Gallus
gallus)
5 / 12 ILE A 278
VAL A 446
VAL A 359
ALA A 431
LEU A 443
None
1.50A 6a7pB-3j04A:
undetectable
6a7pB-3j04A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
3j04 MYOSIN-11
(Gallus
gallus)
3 / 3 THR A 176
GLU A 487
ASN A 708
None
0.86A 6nj9K-3j04A:
undetectable
6nj9K-3j04A:
18.94