SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 6 GLU A 255
THR A 226
ALA A 224
LEU A 222
 None
 1.26A 1etb2-3j09A:
undetectable		 1etb2-3j09A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 9 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 1.07A 1hpvB-3j09A:
undetectable		 1hpvB-3j09A:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 11 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.82A 1t3rB-3j09A:
undetectable		 1t3rB-3j09A:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		3 / 3 ALA A 720
VAL A 718
TRP A 678
 None
 0.99A 1tkqA-3j09A:
undetectable		 1tkqA-3j09A:
2.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 5 LEU A 113
ALA A 116
LEU A 112
SER A 173
 None
 1.15A 1tt6B-3j09A:
undetectable		 1tt6B-3j09A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 420
LEU A 590
SER A 583
LEU A 429
VAL A 558
 None
 1.24A 1u72A-3j09A:
undetectable		 1u72A-3j09A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 5 ASP A 424
GLY A 277
PRO A 624
ALA A 625
 None
 0.60A 2aofA-3j09A:
undetectable		 2aofA-3j09A:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 5 ASP A 424
GLY A 277
PRO A 624
ALA A 625
 None
 0.78A 2aohA-3j09A:
undetectable		 2aohA-3j09A:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 429
GLY A 617
ASP A 647
ASP A 424
ALA A 629
 None
 1.13A 2br4E-3j09A:
2.5		 2br4E-3j09A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A 112
LEU A 113
ILE A 373
LEU A 133
ILE A 136
 None
 1.19A 2f78B-3j09A:
undetectable		 2f78B-3j09A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 9 LEU A 112
LEU A 113
ILE A 373
LEU A 133
ILE A 136
 None
 1.15A 2f7aA-3j09A:
undetectable		 2f7aA-3j09A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.83A 2ienB-3j09A:
undetectable		 2ienB-3j09A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 631
ASP A 424
ILE A 571
GLY A 569
VAL A 568
 None
 1.23A 2o4lA-3j09A:
undetectable		 2o4lA-3j09A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 662
ILE A 406
ALA A 411
ALA A 415
VAL A 418
 None
 1.00A 2qhfA-3j09A:
undetectable		 2qhfA-3j09A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 11 ILE A 662
ILE A 648
ALA A 411
ALA A 415
VAL A 418
 None
 1.08A 2qhfA-3j09A:
undetectable		 2qhfA-3j09A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 521
ILE A 533
ILE A 455
LEU A 450
 None
 0.94A 2xkwB-3j09A:
undetectable		 2xkwB-3j09A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 6 MET A 669
PRO A 731
GLY A 735
MET A 564
 None
 1.48A 3aqiB-3j09A:
undetectable		 3aqiB-3j09A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		3 / 3 MET A 506
VAL A 532
GLU A 491
 None
 0.87A 3c6gA-3j09A:
undetectable		 3c6gA-3j09A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 MET A 669
THR A 668
VAL A 418
VAL A 616
ILE A 648
 None
 1.23A 3dl9A-3j09A:
undetectable		 3dl9A-3j09A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 9 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.86A 3ekvB-3j09A:
undetectable		 3ekvB-3j09A:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 10 ASP A 424
ILE A 620
GLY A 277
PRO A 624
ALA A 625
 None
 0.89A 3ekwA-3j09A:
undetectable		 3ekwA-3j09A:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 10 ILE A 571
ASP A 424
THR A 428
VAL A 635
LEU A 626
 None
 1.45A 3eqmA-3j09A:
undetectable		 3eqmA-3j09A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 420
LEU A 590
LEU A 607
ILE A 571
THR A 419
 None
 0.94A 3fl9G-3j09A:
2.6		 3fl9G-3j09A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.88A 3jvyA-3j09A:
undetectable		 3jvyA-3j09A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 9 ALA A 557
VAL A 421
ILE A 648
LEU A 631
ILE A 662
 None
 1.07A 3jw3B-3j09A:
2.6		 3jw3B-3j09A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 7 ASP A 737
TYR A 728
GLN A 663
GLU A 416
 None
 1.17A 3l2vA-3j09A:
undetectable		 3l2vA-3j09A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.86A 3lzuB-3j09A:
undetectable		 3lzuB-3j09A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 8 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.87A 3nu9A-3j09A:
undetectable		 3nu9A-3j09A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 10 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.97A 3nujA-3j09A:
undetectable		 3nujA-3j09A:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_I_SAMI228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 617
ILE A 633
ASP A 647
ASP A 618
GLU A 278
 None
 1.06A 3nvkI-3j09A:
undetectable		 3nvkI-3j09A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 11 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.92A 3oy4A-3j09A:
undetectable		 3oy4A-3j09A:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 385
ALA A 387
ALA A 391
LEU A 723
ASN A 675
 None
 1.01A 3p5nA-3j09A:
undetectable		 3p5nA-3j09A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 385
ALA A 387
ALA A 391
LEU A 723
ASN A 675
 None
 1.01A 3p5nB-3j09A:
undetectable		 3p5nB-3j09A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 10 ASP A 424
ILE A 620
GLY A 277
PRO A 624
ALA A 625
 None
 1.04A 3t3cB-3j09A:
undetectable		 3t3cB-3j09A:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 372
PHE A 369
PHE A 118
GLY A 109
LEU A 111
 None
 1.15A 3tbgA-3j09A:
2.2		 3tbgA-3j09A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 372
PHE A 369
PHE A 118
GLY A 109
LEU A 111
 None
 1.17A 3tbgC-3j09A:
2.3		 3tbgC-3j09A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 10 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 1.03A 4dqcA-3j09A:
undetectable		 4dqcA-3j09A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.94A 4dqfA-3j09A:
undetectable		 4dqfA-3j09A:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 6 PHE A 369
ILE A 136
PRO A 134
PHE A 126
 None
 1.27A 4fgkA-3j09A:
2.9		 4fgkA-3j09A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 8 ASP A 260
VAL A 249
GLY A 246
ALA A 227
 None
 0.91A 4m48A-3j09A:
undetectable		 4m48A-3j09A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 115
SER A 176
LEU A 171
LEU A 112
 None
 1.09A 4n09A-3j09A:
3.6		 4n09A-3j09A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 10 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.88A 4q1wB-3j09A:
undetectable		 4q1wB-3j09A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_B_STRB601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 9 ALA A 169
ILE A 343
VAL A 339
GLY A 109
ALA A 108
 None
 0.96A 4r21B-3j09A:
undetectable		 4r21B-3j09A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 619
GLY A 617
GLY A 427
ALA A 215
ALA A 623
 None
 0.92A 4uciA-3j09A:
undetectable		 4uciA-3j09A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 619
GLY A 617
GLY A 427
ALA A 215
ALA A 623
 None
 0.94A 4uciB-3j09A:
undetectable		 4uciB-3j09A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 619
GLY A 617
GLY A 427
ALA A 215
ALA A 623
 None
 0.95A 4uckA-3j09A:
undetectable		 4uckA-3j09A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 372
PHE A 118
GLY A 109
LEU A 111
PHE A 170
 None
 1.12A 4wnuA-3j09A:
undetectable		 4wnuA-3j09A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		3 / 3 LYS A 470
ARG A  48
VAL A  49
 None
 1.02A 4x3uA-3j09A:
undetectable
4x3uB-3j09A:
undetectable		 4x3uA-3j09A:
7.28
4x3uB-3j09A:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 617
GLY A 427
ASP A 424
LEU A 650
LEU A 626
 None
 1.16A 5bw4A-3j09A:
undetectable		 5bw4A-3j09A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 6 ALA A 465
VAL A 469
VAL A 280
HIS A 462
 None
 1.07A 5eckA-3j09A:
2.0		 5eckA-3j09A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		3 / 3 GLY A 310
GLY A 309
GLN A 223
 None
 0.26A 5imsA-3j09A:
4.4		 5imsA-3j09A:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 7 THR A 426
HIS A 462
PRO A 463
ILE A 464
 None
 1.15A 5vkqA-3j09A:
2.5
5vkqB-3j09A:
2.4		 5vkqA-3j09A:
19.08
5vkqB-3j09A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 8 THR A 426
HIS A 462
PRO A 463
ILE A 464
 None
 1.12A 5vkqB-3j09A:
2.4
5vkqC-3j09A:
2.5		 5vkqB-3j09A:
19.08
5vkqC-3j09A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		4 / 7 THR A 426
HIS A 462
PRO A 463
ILE A 464
 None
 1.10A 5vkqC-3j09A:
2.5
5vkqD-3j09A:
2.5		 5vkqC-3j09A:
19.08
5vkqD-3j09A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.88A 6dgxB-3j09A:
undetectable		 6dgxB-3j09A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 ASP A 288
VAL A 290
ILE A 250
PRO A 258
VAL A 259
 None
 0.88A 6dh0B-3j09A:
undetectable		 6dh0B-3j09A:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3j09 COPPER-EXPORTING
P-TYPE ATPASE A
(Archaeoglobus
fulgidus) 		5 / 12 VAL A 280
HIS A 462
VAL A 487
LEU A 450
ALA A 453
 None
 1.16A 6djzA-3j09A:
1.8		 6djzA-3j09A:
16.46