SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 4 THR B  65
LEU B  79
VAL B  82
LEU B  84
 None
 1.11A 1fbmB-3j0cB:
undetectable		 1fbmB-3j0cB:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 5 VAL B 237
THR B  12
GLN B  52
ILE B  74
 None
 0.95A 1ss4A-3j0cB:
undetectable		 1ss4A-3j0cB:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		5 / 12 GLY A 182
TYR A 262
ALA A 119
ALA A 181
TYR A 180
 None
 1.41A 2avdA-3j0cA:
undetectable		 2avdA-3j0cA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W13_A_ACTA1208_0
(ZINC
METALLOPROTEINASE
BAP1)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 4 THR B 293
ARG B 136
GLU B 137
ASN B 332
 None
 1.28A 2w13A-3j0cB:
0.0		 2w13A-3j0cB:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 8 LEU A  27
PHE A 287
VAL A 159
ALA A 285
 None
 0.91A 3ax9A-3j0cA:
undetectable		 3ax9A-3j0cA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		5 / 8 GLY A  91
GLY A  90
HIS B  71
SER B 177
SER B 176
 None
 1.05A 3d41A-3j0cA:
undetectable		 3d41A-3j0cA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		3 / 3 ILE A 177
PHE A 189
HIS A 125
 None
 0.63A 3h0aA-3j0cA:
undetectable		 3h0aA-3j0cA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		3 / 3 LEU B 285
TRP B 330
GLY B 331
 None
 0.77A 3l35A-3j0cB:
undetectable
3l35H-3j0cB:
undetectable		 3l35A-3j0cB:
6.78
3l35H-3j0cB:
2.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		3 / 3 LEU B 285
TRP B 330
GLY B 331
 None
 0.79A 3l35B-3j0cB:
1.3
3l35K-3j0cB:
undetectable		 3l35B-3j0cB:
6.78
3l35K-3j0cB:
2.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_1
(MNMC2)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 6 GLY B  63
ASP B  56
ASN B   7
GLU B   8
 None
 1.06A 3vywC-3j0cB:
undetectable		 3vywC-3j0cB:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		3 / 3 TYR A  51
THR A 217
GLU A 241
 None
 0.75A 4df3A-3j0cA:
undetectable		 4df3A-3j0cA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		3 / 3 TYR A  51
THR A 217
GLU A 241
 None
 0.77A 4df3B-3j0cA:
undetectable		 4df3B-3j0cA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		5 / 11 LEU A 133
ILE A  31
LEU A 278
LEU A 166
ILE A  36
 None
 1.09A 4dm8A-3j0cA:
undetectable		 4dm8A-3j0cA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		5 / 11 PHE A 312
PHE A 356
LEU A 303
THR A 353
ALA A 352
 None
 1.40A 4dx7A-3j0cA:
undetectable		 4dx7A-3j0cA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 4 LEU B 412
ILE B 408
PRO B 399
LEU B 397
 None
 1.09A 5eb3A-3j0cB:
undetectable		 5eb3A-3j0cB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 7 GLY B  40
HIS B  41
HIS A  50
ASP B  39
 None
 1.02A 5no9D-3j0cB:
undetectable		 5no9D-3j0cB:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 5 ARG B  67
MET B  66
THR B  65
LEU B  79
 None
 1.41A 5w97J-3j0cB:
undetectable		 5w97J-3j0cB:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3j0c E1 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 5 ALA A 395
TYR A 393
GLN A  10
ILE A  13
 None
 1.27A 6g9bA-3j0cA:
undetectable
6g9bB-3j0cA:
undetectable		 6g9bA-3j0cA:
11.79
6g9bB-3j0cA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j0c E2 ENVELOPE
GLYCOPROTEIN
(Venezuelan
equine
encephalitis
virus) 		4 / 5 ARG B  67
MET B  66
THR B  65
LEU B  79
 None
 1.20A 6nknW-3j0cB:
undetectable		 6nknW-3j0cB:
10.71