SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 4 ILE A 355
LEU A 189
VAL A 314
ILE A 113
 None
 0.87A 1fm6D-3j0hA:
undetectable		 1fm6D-3j0hA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 7 TYR A 374
VAL A 249
ILE A 248
GLU A 241
 None
 1.06A 1j96B-3j0hA:
undetectable		 1j96B-3j0hA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 11 ILE A 318
VAL A 314
SER A 210
LEU A 342
ILE A 113
 None
 1.26A 1pkvA-3j0hA:
undetectable
1pkvB-3j0hA:
undetectable		 1pkvA-3j0hA:
15.79
1pkvB-3j0hA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 8 LEU A 107
TYR A 374
GLY A 377
LEU A 157
 None
 0.86A 1s1xA-3j0hA:
undetectable		 1s1xA-3j0hA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		3 / 3 ARG A 106
SER A 286
TYR A 285
 None
 0.77A 1x70A-3j0hA:
undetectable		 1x70A-3j0hA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		3 / 3 ARG A 154
GLU A 112
SER A 376
 None
 0.92A 2xctD-3j0hA:
undetectable		 2xctD-3j0hA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 5 ILE A 108
PHE A 304
PRO A 188
PHE A 341
 None
 1.10A 2ygnA-3j0hA:
undetectable		 2ygnA-3j0hA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 7 ILE A 365
ILE A 355
LEU A 157
LEU A 175
 None
 0.95A 3adxA-3j0hA:
undetectable		 3adxA-3j0hA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 6 ILE A 373
THR A 343
PHE A 232
PHE A 262
 None
 1.24A 3elzB-3j0hA:
undetectable		 3elzB-3j0hA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.10A 3kkzA-3j0hA:
undetectable		 3kkzA-3j0hA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.08A 3kkzB-3j0hA:
undetectable		 3kkzB-3j0hA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 6 VAL A 277
VAL A 109
ILE A 311
ARG A 233
 None
 1.00A 3ms9A-3j0hA:
undetectable		 3ms9A-3j0hA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 6 VAL A 277
VAL A 109
ILE A 311
ARG A 233
 None
 1.03A 3mssA-3j0hA:
undetectable		 3mssA-3j0hA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 6 VAL A 277
VAL A 109
ILE A 311
ARG A 233
 None
 1.02A 3mssC-3j0hA:
undetectable		 3mssC-3j0hA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.16A 3sxjB-3j0hA:
undetectable		 3sxjB-3j0hA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.13A 3t7sA-3j0hA:
undetectable		 3t7sA-3j0hA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.12A 3t7sB-3j0hA:
undetectable		 3t7sB-3j0hA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.11A 3t7sC-3j0hA:
undetectable		 3t7sC-3j0hA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A 378
SER A 195
GLU A 159
ALA A 375
ASN A 204
 None
 1.12A 3t7sD-3j0hA:
undetectable		 3t7sD-3j0hA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		3 / 3 ARG A 315
GLU A 338
THR A 229
 None
 0.85A 3v4tA-3j0hA:
undetectable		 3v4tA-3j0hA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 SER A 105
ASN A 103
GLY A 381
ASP A 380
GLY A 377
 None
 1.14A 4pevB-3j0hA:
undetectable		 4pevB-3j0hA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		5 / 12 GLU A 218
ASP A 215
GLU A 221
ASN A 259
TYR A 257
 None
 1.35A 4wa5A-3j0hA:
undetectable		 4wa5A-3j0hA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 7 ILE A 248
VAL A 249
TYR A 285
GLN A 254
 None
 1.25A 5kkzC-3j0hA:
undetectable
5kkzE-3j0hA:
undetectable		 5kkzC-3j0hA:
22.11
5kkzE-3j0hA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 7 ILE A 248
VAL A 249
TYR A 285
GLN A 254
 None
 1.25A 5kkzK-3j0hA:
undetectable
5kkzQ-3j0hA:
undetectable		 5kkzK-3j0hA:
23.54
5kkzQ-3j0hA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		4 / 7 ILE A 248
VAL A 249
TYR A 285
GLN A 254
 None
 1.21A 5kkzM-3j0hA:
undetectable
5kkzO-3j0hA:
undetectable		 5kkzM-3j0hA:
22.11
5kkzO-3j0hA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		3 / 3 LEU A 157
GLY A 364
PHE A 344
 None
 0.59A 6exiC-3j0hA:
undetectable		 6exiC-3j0hA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA819_0
(GEPHYRIN)		 3j0h PHIKZ029
(Pseudomonas
virus
phiKZ) 		3 / 3 ARG A 315
GLY A 337
GLU A 338
 None
 0.57A 6fgdA-3j0hA:
undetectable		 6fgdA-3j0hA:
21.58