SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3j0l RIBOSOMAL PROTEIN S5
(Oryctolagus
cuniculus) 		5 / 11 LEU T  67
GLU T 171
ILE T 172
LEU T  13
LEU T 104
 None
 1.28A 1mrqA-3j0lT:
undetectable		 1mrqA-3j0lT:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 10 ILE K  42
ALA K  77
ALA K  74
GLN K  76
ILE K  95
 None
 1.10A 2aclC-3j0lK:
undetectable		 2aclC-3j0lK:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 11 ILE K  42
ALA K  77
ALA K  74
GLN K  76
ILE K  95
 None
 1.07A 2aclE-3j0lK:
undetectable		 2aclE-3j0lK:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		4 / 9 ALA K  78
VAL K  81
CYH K  85
LYS K  86
 None
 0.97A 2vufB-3j0lK:
undetectable		 2vufB-3j0lK:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 10 ILE K  42
ALA K  77
ALA K  74
GLN K  76
ILE K  95
 None
 1.09A 3falA-3j0lK:
undetectable		 3falA-3j0lK:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		3 / 3 LYS K  96
VAL K  30
HIS K  94
 None
 1.18A 3tj7A-3j0lK:
undetectable		 3tj7A-3j0lK:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		4 / 6 ALA K  92
LEU K  93
VAL K  30
GLU K 130
 None
 1.05A 4g24A-3j0lK:
undetectable		 4g24A-3j0lK:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 10 ALA K 118
ALA K 112
GLY K 111
ALA K  74
THR K  40
 None
 1.09A 5lf3H-3j0lK:
undetectable
5lf3I-3j0lK:
undetectable		 5lf3H-3j0lK:
20.18
5lf3I-3j0lK:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 10 ALA K 118
ALA K 112
GLY K 111
ALA K  74
THR K  40
 None
 1.11A 5lf3V-3j0lK:
undetectable
5lf3W-3j0lK:
undetectable		 5lf3V-3j0lK:
20.18
5lf3W-3j0lK:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 11 ALA K 118
ALA K 112
GLY K 111
ALA K  74
THR K  40
 None
 1.07A 5lf7H-3j0lK:
undetectable
5lf7I-3j0lK:
undetectable		 5lf7H-3j0lK:
20.18
5lf7I-3j0lK:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3j0l RIBOSOMAL PROTEIN
S14
(Oryctolagus
cuniculus) 		5 / 11 ALA K 118
ALA K 112
GLY K 111
ALA K  74
THR K  40
 None
 1.07A 5lf7V-3j0lK:
undetectable
5lf7W-3j0lK:
undetectable		 5lf7V-3j0lK:
20.18
5lf7W-3j0lK:
23.92