SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3j0o RIBOSOMAL PROTEIN
S15
(Oryctolagus
cuniculus) 		3 / 3 LEU S  41
LEU S  38
SER S  35
 None
 0.67A 1tlmA-3j0oS:
undetectable		 1tlmA-3j0oS:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3j0o RIBOSOMAL PROTEIN
S23
(Oryctolagus
cuniculus) 		4 / 7 VAL L 101
ALA L  84
VAL L 103
GLY L  50
 None
 0.79A 2xrzB-3j0oL:
undetectable		 2xrzB-3j0oL:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3j0o RIBOSOMAL PROTEIN
S15
(Oryctolagus
cuniculus) 		4 / 8 GLY S  96
LYS S 113
ARG S  14
PRO S  78
 None
 0.75A 4j4vC-3j0oS:
undetectable		 4j4vC-3j0oS:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 3j0o RIBOSOMAL PROTEIN
S15
(Oryctolagus
cuniculus) 		5 / 12 LEU S  24
GLY S  27
SER S  26
LEU S  33
GLU S  93
 None
 1.32A 5nwvA-3j0oS:
undetectable		 5nwvA-3j0oS:
28.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3j0o RIBOSOMAL PROTEIN
S23
(Oryctolagus
cuniculus) 		3 / 3 ALA L  48
PHE L 121
GLN L 109
 None
 0.68A 6eceA-3j0oL:
undetectable		 6eceA-3j0oL:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3j0o RIBOSOMAL PROTEIN
S15
(Oryctolagus
cuniculus) 		5 / 12 ARG S  49
VAL S  50
ILE S  34
VAL S  90
ILE S  91
 None
 1.19A 6gsdA-3j0oS:
undetectable		 6gsdA-3j0oS:
18.25