SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 11 PHE A 105
TYR A 447
LEU A 425
THR A 509
VAL A 512
 None
 1.28A 1akdA-3j1cA:
2.1		 1akdA-3j1cA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.10A 1dz4A-3j1cA:
undetectable		 1dz4A-3j1cA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.11A 1dz4B-3j1cA:
undetectable		 1dz4B-3j1cA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.07A 1dz6A-3j1cA:
undetectable		 1dz6A-3j1cA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 7 SER A 397
PHE A 170
ALA A 394
ILE A 217
 None
 0.95A 1fxhA-3j1cA:
undetectable
1fxhB-3j1cA:
undetectable		 1fxhA-3j1cA:
15.94
1fxhB-3j1cA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 GLU A 254
LEU A 253
VAL A 287
MET A 286
 None
 0.90A 1hk1A-3j1cA:
undetectable		 1hk1A-3j1cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 7 GLU A 254
LEU A 253
VAL A 287
MET A 286
 None
 0.90A 1hk2A-3j1cA:
1.4		 1hk2A-3j1cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 ARG A 406
ASP A  93
ASN A  61
 None
 0.85A 1nbhA-3j1cA:
undetectable		 1nbhA-3j1cA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 ARG A 406
ASP A  93
ASN A  61
 None
 0.85A 1nbhD-3j1cA:
undetectable		 1nbhD-3j1cA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 10 PHE A 105
TYR A 447
LEU A 425
THR A 509
VAL A 512
 None
 1.41A 1o76A-3j1cA:
undetectable		 1o76A-3j1cA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 GLU A 332
ASP A 327
ILE A 328
ASP A 250
 None
 0.87A 1p7lD-3j1cA:
undetectable		 1p7lD-3j1cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 GLU A 332
ASP A 327
ILE A 328
ASP A 250
 None
 0.88A 1p7lC-3j1cA:
undetectable		 1p7lC-3j1cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_SAMA635_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 GLY A 419
GLY A 418
GLY A 417
GLU A 422
ASN A 483
 None
 1.15A 1qzzA-3j1cA:
undetectable		 1qzzA-3j1cA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 GLU A 332
ASP A 327
ILE A 328
ASP A 250
 None
 0.88A 1rg9B-3j1cA:
undetectable		 1rg9B-3j1cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 GLU A 332
ASP A 327
ILE A 328
ASP A 250
 None
 0.89A 1rg9A-3j1cA:
undetectable		 1rg9A-3j1cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 GLU A 332
ASP A 327
ILE A 328
ASP A 250
 None
 0.88A 1rg9D-3j1cA:
undetectable		 1rg9D-3j1cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 GLU A 332
ASP A 327
ILE A 328
ASP A 250
 None
 0.88A 1rg9C-3j1cA:
undetectable		 1rg9C-3j1cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 ASP A 229
LEU A 228
VAL A 227
ILE A 226
 None
 1.02A 1s9qA-3j1cA:
undetectable		 1s9qA-3j1cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.09A 1t88B-3j1cA:
undetectable		 1t88B-3j1cA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 SER A 522
MET A 524
VAL A  99
ALA A  34
ALA A  30
 None
 1.32A 2avdB-3j1cA:
undetectable		 2avdB-3j1cA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 ALA A 443
ALA A 129
LYS A 128
VAL A 436
 None
 0.81A 2bxgA-3j1cA:
undetectable		 2bxgA-3j1cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.07A 2m56A-3j1cA:
undetectable		 2m56A-3j1cA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.09A 2zawA-3j1cA:
undetectable		 2zawA-3j1cA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 513
GLY A 417
VAL A 502
GLY A 485
LEU A 458
 None
 1.00A 3ku1H-3j1cA:
undetectable		 3ku1H-3j1cA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.12A 3wrjE-3j1cA:
undetectable		 3wrjE-3j1cA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 ILE A 226
ILE A 370
VAL A 248
GLY A 352
 None
 0.78A 4acaC-3j1cA:
undetectable		 4acaC-3j1cA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 GLY A 418
GLY A 419
GLU A 504
VAL A 508
ILE A 421
 None
 1.02A 4fglA-3j1cA:
undetectable
4fglB-3j1cA:
undetectable		 4fglA-3j1cA:
17.98
4fglB-3j1cA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.11A 4g3rA-3j1cA:
undetectable		 4g3rA-3j1cA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.08A 4g3rB-3j1cA:
undetectable		 4g3rB-3j1cA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.13A 4kkyX-3j1cA:
undetectable		 4kkyX-3j1cA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 PHE A 105
TYR A 447
LEU A 425
VAL A 512
 None
 1.11A 4l49A-3j1cA:
1.8		 4l49A-3j1cA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 ILE A 493
GLY A 419
GLY A 485
ILE A 421
LEU A 451
 None
 1.10A 4mwzA-3j1cA:
undetectable		 4mwzA-3j1cA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 10 THR A 517
ILE A 454
GLU A 422
LEU A 134
LEU A 429
 None
 1.34A 4r3aB-3j1cA:
undetectable		 4r3aB-3j1cA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 SER A 111
ARG A  20
ILE A 122
PRO A 119
ILE A 121
 None
 1.37A 4uroB-3j1cA:
undetectable		 4uroB-3j1cA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 9 PHE A 105
TYR A 447
LEU A 425
THR A 509
VAL A 512
 None
 1.27A 5cp4A-3j1cA:
undetectable		 5cp4A-3j1cA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 11 VAL A 146
SER A 147
ASP A 148
PRO A 412
TYR A 200
 None
 1.16A 5jh7B-3j1cA:
undetectable		 5jh7B-3j1cA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 7 LEU A 283
ILE A 317
LYS A 289
VAL A 287
 None
 1.14A 5jh7C-3j1cA:
undetectable		 5jh7C-3j1cA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 GLY A 417
GLU A 452
GLU A 422
LEU A 451
LEU A 425
 None
 1.26A 5nwvA-3j1cA:
undetectable		 5nwvA-3j1cA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 228
LEU A 331
ILE A 223
ALA A 373
LEU A 356
 None
 1.07A 5og9B-3j1cA:
1.8		 5og9B-3j1cA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 ARG A 428
ARG A 434
ARG A 474
 None
 0.93A 5vcgA-3j1cA:
undetectable		 5vcgA-3j1cA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 ARG A  20
LYS A  24
ARG A  38
 None
 1.09A 6c06D-3j1cA:
undetectable		 6c06D-3j1cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3j1c CHAPERONIN ALPHA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 10 GLY A  42
GLY A 418
GLU A 504
THR A 165
THR A 164
 None
 1.49A 6nmfG-3j1cA:
undetectable
6nmfN-3j1cA:
0.0
6nmfO-3j1cA:
undetectable		 6nmfG-3j1cA:
11.62
6nmfN-3j1cA:
20.33
6nmfO-3j1cA:
18.23