SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 LYS A 163
MET A 166
ALA A 182
GLU A 179
 None
 1.15A 1qhyA-3j1eA:
undetectable		 1qhyA-3j1eA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 ASP A 125
LYS A  28
ARG A  33
 None
 0.95A 1ra8A-3j1eA:
undetectable		 1ra8A-3j1eA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 ILE A 383
THR A 220
ASP A 219
GLY A 386
GLY A 215
 None
 1.04A 1rjdA-3j1eA:
undetectable		 1rjdA-3j1eA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 ILE A 383
THR A 220
ASP A 219
GLY A 386
GLY A 215
 None
 1.04A 1rjdB-3j1eA:
undetectable		 1rjdB-3j1eA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 ILE A 383
THR A 220
ASP A 219
GLY A 386
GLY A 215
 None
 1.02A 1rjdC-3j1eA:
undetectable		 1rjdC-3j1eA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 THR A 335
VAL A 297
VAL A 228
VAL A 368
 None
 0.86A 1t86A-3j1eA:
undetectable		 1t86A-3j1eA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 10 THR A 220
ASP A 219
GLY A 385
GLY A 215
ALA A 177
 None
 0.90A 1x7pA-3j1eA:
undetectable
1x7pB-3j1eA:
undetectable		 1x7pA-3j1eA:
21.84
1x7pB-3j1eA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 LEU A 402
ARG A 399
ALA A 401
ILE A 209
 None
 0.91A 2qhfA-3j1eA:
undetectable		 2qhfA-3j1eA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 SER A 133
THR A 521
PHE A 110
 None
 0.69A 2x91A-3j1eA:
undetectable		 2x91A-3j1eA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 7 VAL A 405
ILE A 164
VAL A 185
GLY A 403
THR A 404
 None
 1.23A 2xrzB-3j1eA:
undetectable		 2xrzB-3j1eA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 ASP A 157
LEU A 160
GLN A 499
 None
 0.59A 3g4lA-3j1eA:
undetectable		 3g4lA-3j1eA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 398
ALA A 193
ALA A 165
SER A 168
LEU A 169
 None
 0.85A 3ln1A-3j1eA:
undetectable		 3ln1A-3j1eA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 398
ALA A 193
ALA A 165
SER A 168
LEU A 169
 None
 0.85A 3ln1B-3j1eA:
undetectable		 3ln1B-3j1eA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 398
ALA A 193
ALA A 165
SER A 168
LEU A 169
 None
 0.86A 3ln1C-3j1eA:
1.5		 3ln1C-3j1eA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		6 / 12 LEU A 524
THR A 521
GLY A 134
ALA A 443
ALA A 446
LEU A 121
 None
 1.38A 3p5nA-3j1eA:
undetectable		 3p5nA-3j1eA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		6 / 12 LEU A 524
THR A 521
GLY A 134
ALA A 443
ALA A 446
LEU A 121
 None
 1.38A 3p5nB-3j1eA:
undetectable		 3p5nB-3j1eA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 473
ILE A 423
LEU A 451
ILE A 425
ALA A 142
 None
 1.03A 3uwlB-3j1eA:
undetectable		 3uwlB-3j1eA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 6 ALA A 519
GLY A 112
LEU A  89
VAL A  39
 None
 0.91A 4dubB-3j1eA:
undetectable		 4dubB-3j1eA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 THR A 335
VAL A 297
VAL A 228
VAL A 368
 None
 0.98A 4l4bA-3j1eA:
undetectable		 4l4bA-3j1eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 ALA A 295
ASP A 250
ILE A 249
ILE A 343
 None
 0.92A 4ndnB-3j1eA:
undetectable		 4ndnB-3j1eA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 8 ALA A 295
ASP A 250
ILE A 249
ILE A 343
 None
 0.89A 4ndnD-3j1eA:
undetectable		 4ndnD-3j1eA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 GLN A 191
ILE A 379
ILE A 381
TYR A 224
 None
 1.13A 5dnuA-3j1eA:
undetectable		 5dnuA-3j1eA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 5 GLN A 191
ILE A 379
ILE A 381
TYR A 224
 None
 1.06A 5dnvA-3j1eA:
undetectable		 5dnvA-3j1eA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 222
ILE A 209
GLY A 403
ILE A 379
ILE A 381
 None
 0.88A 5e5kB-3j1eA:
undetectable		 5e5kB-3j1eA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 ILE A 357
VAL A 317
ALA A 308
LEU A 253
GLY A 303
 None
 1.06A 5igtA-3j1eA:
undetectable		 5igtA-3j1eA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 12 LEU A 398
ALA A 193
ALA A 165
SER A 168
LEU A 169
 None
 0.89A 5jw1A-3j1eA:
2.0		 5jw1A-3j1eA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 10 THR A 394
THR A 220
GLY A 386
ALA A 213
ASP A 365
 None
 1.39A 5l66K-3j1eA:
undetectable
5l66L-3j1eA:
undetectable		 5l66K-3j1eA:
15.97
5l66L-3j1eA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		5 / 10 THR A 394
THR A 220
GLY A 386
ALA A 213
ASP A 365
 None
 1.40A 5l66Y-3j1eA:
undetectable
5l66Z-3j1eA:
undetectable		 5l66Y-3j1eA:
15.97
5l66Z-3j1eA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		3 / 3 LEU A 402
ILE A 207
TYR A 224
 None
 0.70A 5uunB-3j1eA:
undetectable		 5uunB-3j1eA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3j1e CHAPERONIN BETA
SUBUNIT
(Acidianus
tengchongensis) 		4 / 9 LEU A 328
VAL A 340
SER A 341
ASP A 350
 None
 0.99A 6c2mD-3j1eA:
undetectable		 6c2mD-3j1eA:
9.90