SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 3j23 CAPSID PROTEIN VP1
CAPSID PROTEIN VP3
(Enterovirus
A;
Enterovirus
A) 		5 / 12 PHE C 224
GLN C 221
ILE C 172
LEU C 115
THR A  75
 None
 1.18A 1dhfA-3j23C:
undetectable		 1dhfA-3j23C:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 3j23 CAPSID PROTEIN VP3
(Enterovirus
A) 		4 / 8 VAL C 165
THR C 166
VAL C 194
ILE C 196
 None
 0.92A 2qbmA-3j23C:
undetectable		 2qbmA-3j23C:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3j23 CAPSID PROTEIN VP3
(Enterovirus
A) 		5 / 11 THR C 153
ILE C 133
LEU C 167
ILE C 169
VAL C  55
 None
 1.17A 3a51A-3j23C:
undetectable		 3a51A-3j23C:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3j23 CAPSID PROTEIN VP3
(Enterovirus
A) 		5 / 12 THR C 153
ILE C 133
LEU C 167
ILE C 169
VAL C  55
 None
 1.22A 3a51D-3j23C:
undetectable		 3a51D-3j23C:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3j23 CAPSID PROTEIN VP1
(Enterovirus
A) 		3 / 3 TRP A 109
VAL A 123
ARG A 264
 None
 0.76A 3b0wA-3j23A:
undetectable		 3b0wA-3j23A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 3j23 CAPSID PROTEIN VP1
(Enterovirus
A) 		4 / 5 VAL A 249
VAL A 248
THR A 237
ARG A 250
 None
 1.16A 3bjwG-3j23A:
undetectable		 3bjwG-3j23A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 3j23 CAPSID PROTEIN VP3
(Enterovirus
A) 		5 / 11 LEU C  53
ALA C 216
ASN C  56
ALA C  84
VAL C 194
 None
 1.28A 3e22B-3j23C:
undetectable		 3e22B-3j23C:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3j23 CAPSID PROTEIN VP3
(Enterovirus
A) 		5 / 11 LEU C  53
ALA C 216
ASN C  56
ALA C  84
VAL C 194
 None
 1.29A 3e22D-3j23C:
undetectable		 3e22D-3j23C:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3j23 CAPSID PROTEIN VP1
CAPSID PROTEIN VP3
(Enterovirus
A;
Enterovirus
A) 		5 / 12 MET A 129
PHE A 204
PHE A 126
LEU C  43
GLY C 106
 None
 0.96A 4zjlA-3j23A:
undetectable		 4zjlA-3j23A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3j23 CAPSID PROTEIN VP1
CAPSID PROTEIN VP3
(Enterovirus
A;
Enterovirus
A) 		4 / 8 ILE A 294
VAL C  55
PRO C  59
ALA C 216
 None
 0.89A 6cduD-3j23A:
undetectable
6cduE-3j23A:
undetectable		 6cduD-3j23A:
19.64
6cduE-3j23A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3j23 CAPSID PROTEIN VP1
CAPSID PROTEIN VP3
(Enterovirus
A;
Enterovirus
A) 		4 / 7 ALA C 216
ILE A 294
VAL C  55
PRO C  59
 None
 0.84A 6cduF-3j23C:
undetectable
6cduJ-3j23C:
undetectable		 6cduF-3j23C:
21.47
6cduJ-3j23C:
21.47