SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 ILE A 127
ALA A 124
ARG A 240
PRO A 348
ARG A 132
 None
 1.29A 1u70A-3j26A:
undetectable		 1u70A-3j26A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 5 ILE A 472
SER A  58
LEU A 225
ASN A 115
 None
 0.94A 1y0xX-3j26A:
undetectable		 1y0xX-3j26A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 TYR N 182
PRO N 157
ILE N 191
VAL N 225
LEU N 222
 None
 1.45A 1z9hB-3j26N:
undetectable		 1z9hB-3j26N:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 8 PHE N  31
TYR N 132
TYR N 134
TRP N 341
 None
 1.41A 2aoxA-3j26N:
undetectable		 2aoxA-3j26N:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 8 GLY A  94
ARG A  95
THR A 248
ILE A 247
 None
 0.87A 2f9wA-3j26A:
undetectable
2f9wB-3j26A:
undetectable		 2f9wA-3j26A:
18.76
2f9wB-3j26A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 11 LEU A 130
ARG A 132
ILE A 127
PHE A 101
ASP A 349
 None
 1.25A 2qeiA-3j26A:
undetectable		 2qeiA-3j26A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 7 SER A 243
HIS A 128
ARG A 182
TYR A 157
 None
 1.47A 2vmyA-3j26A:
undetectable
2vmyB-3j26A:
undetectable		 2vmyA-3j26A:
21.10
2vmyB-3j26A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 11 ALA N 317
PHE N 299
THR N 360
ILE N  60
THR N 318
 None
 1.14A 2w3aA-3j26N:
undetectable		 2w3aA-3j26N:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 11 ILE A 106
LEU A 238
ILE A 262
VAL A  71
LEU A 203
 None
 1.23A 3a51A-3j26A:
undetectable		 3a51A-3j26A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 ILE A 106
LEU A 238
ILE A 262
VAL A  71
LEU A 203
 None
 1.22A 3a51D-3j26A:
undetectable		 3a51D-3j26A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		3 / 3 ARG A 285
VAL A 483
THR A 469
 None
 0.79A 3cyxA-3j26A:
undetectable		 3cyxA-3j26A:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		3 / 3 ASN A 438
ASN A 362
GLU A 431
 None
 0.87A 3kpdC-3j26A:
undetectable		 3kpdC-3j26A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		3 / 3 ASN A 438
ASN A 362
GLU A 431
 None
 0.92A 3kpdB-3j26A:
undetectable		 3kpdB-3j26A:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 8 ILE A 103
ILE A 106
VAL A  71
ILE A 262
 None
 0.78A 3p4wC-3j26A:
undetectable		 3p4wC-3j26A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 9 ALA A 100
PHE A 101
TYR A 385
ASN A 386
ARG A 132
 None
 1.44A 3rukC-3j26A:
0.0		 3rukC-3j26A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		3 / 3 PHE N 103
TYR N 134
LEU N 199
 None
 0.80A 3sueB-3j26N:
undetectable		 3sueB-3j26N:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 ILE A 257
THR A 256
THR A 191
VAL A 189
ASP A  96
 None
 1.39A 4i41A-3j26A:
undetectable		 4i41A-3j26A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		3 / 3 THR N  83
ASN N 144
PHE N 165
 None
 0.68A 4pd9A-3j26N:
undetectable		 4pd9A-3j26N:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 5 ILE N 209
ARG N 185
TYR N 194
GLU N 192
 None
 1.28A 4zzcE-3j26N:
undetectable		 4zzcE-3j26N:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 8 PRO A 102
PHE A  98
SER A 243
TYR A 157
 None
 1.05A 5amiB-3j26A:
undetectable		 5amiB-3j26A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 LEU A 180
PHE A 171
ASP A 161
ARG A  95
ALA A 174
 None
 1.17A 5h5fA-3j26A:
undetectable		 5h5fA-3j26A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 11 PRO A 210
LEU A 293
TYR A 507
TRP A 214
LEU A 130
 None
 1.34A 5hbmA-3j26A:
undetectable		 5hbmA-3j26A:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 MET A 460
ILE A 354
LEU A 328
LEU A 359
VAL A 443
 None
 1.25A 5im2A-3j26A:
undetectable		 5im2A-3j26A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		5 / 12 VAL A 119
LEU A 470
LEU A 222
PHE A 212
LEU A 209
 None
 1.34A 6a7pB-3j26A:
undetectable		 6a7pB-3j26A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 3j26 MINOR VIRION PROTEIN
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 6 TYR N 130
VAL N 125
VAL N 127
THR N 128
 None
 1.32A 6f32B-3j26N:
undetectable		 6f32B-3j26N:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 3j26 CAPSID PROTEIN V20
(Mimivirus-depend
ent
virus
Sputnik) 		4 / 6 TYR A 327
HIS A 134
ASN A 386
TYR A 385
 None
 1.47A 6gneA-3j26A:
undetectable		 6gneA-3j26A:
20.56