SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 3j2j PROTEIN VP2
(Enterovirus
B) 		4 / 8 PRO C  47
LEU C  82
GLY C  81
PRO C 238
 None
 0.91A 1ya4A-3j2jC:
undetectable		 1ya4A-3j2jC:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 3j2j PROTEIN VP2
(Enterovirus
B) 		4 / 7 PRO C  47
LEU C  82
GLY C  81
PRO C 238
 None
 0.92A 1ya4B-3j2jC:
undetectable		 1ya4B-3j2jC:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3j2j PROTEIN VP3
PROTEIN VP2
(Enterovirus
B;
Enterovirus
B) 		4 / 5 PRO B  54
GLY C 171
ASN C 172
GLY C 169
 None
 1.19A 1zlqA-3j2jB:
undetectable		 1zlqA-3j2jB:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3j2j PROTEIN VP1
PROTEIN VP3
PROTEIN VP2
(Enterovirus
B;
Enterovirus
B;
Enterovirus
B) 		5 / 12 HIS C 207
PRO C 119
VAL A 187
ILE B  36
SER C 198
 None
 1.46A 2fj1A-3j2jC:
undetectable		 2fj1A-3j2jC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 3j2j PROTEIN VP1
PROTEIN VP3
(Enterovirus
B;
Enterovirus
B) 		5 / 12 PHE B  13
PHE A 178
ILE A  33
ALA B  24
ALA A 117
 None
 1.16A 2j0dA-3j2jB:
undetectable		 2j0dA-3j2jB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3j2j PROTEIN VP2
(Enterovirus
B) 		4 / 6 GLY C 140
GLY C  84
GLN C  88
PHE C 205
 None
 1.04A 2qx6A-3j2jC:
undetectable
2qx6B-3j2jC:
undetectable		 2qx6A-3j2jC:
19.62
2qx6B-3j2jC:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TRT_A_TACA222_1
(TETRACYCLINE
REPRESSOR CLASS D)		 3j2j PROTEIN VP1
PROTEIN VP2
PROTEIN VP3
(Enterovirus
B) 		5 / 11 HIS C 207
PRO C 119
VAL A 187
ILE B  36
SER C 198
 None
 1.46A 2trtA-3j2jC:
undetectable		 2trtA-3j2jC:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VKE_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3j2j PROTEIN VP1
PROTEIN VP2
PROTEIN VP3
(Enterovirus
B) 		5 / 11 HIS C 207
PRO C 119
VAL A 187
ILE B  36
SER C 198
 None
 1.48A 2vkeA-3j2jC:
undetectable		 2vkeA-3j2jC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3j2j PROTEIN VP1
PROTEIN VP2
PROTEIN VP3
(Enterovirus
B) 		5 / 12 HIS C 207
PRO C 119
VAL A 187
ILE B  36
SER C 198
 None
 1.44A 2xpvA-3j2jC:
undetectable		 2xpvA-3j2jC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3j2j PROTEIN VP1
(Enterovirus
B) 		5 / 12 ALA A 115
PRO A 116
GLY A 113
LEU A  78
VAL A  77
 None
 1.21A 2zifB-3j2jA:
undetectable		 2zifB-3j2jA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3j2j PROTEIN VP3
(Enterovirus
B) 		5 / 11 THR B 152
ILE B 132
LEU B 166
VAL B  55
LEU B  85
 None
 1.22A 3a51A-3j2jB:
undetectable		 3a51A-3j2jB:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW5_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3j2j PROTEIN VP2
(Enterovirus
B) 		5 / 10 ALA C  95
LEU C  77
ILE C  99
LEU C 212
PHE C 210
 None
 1.15A 3jw5B-3j2jC:
undetectable		 3jw5B-3j2jC:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3j2j PROTEIN VP2
PROTEIN VP3
(Enterovirus
B) 		4 / 6 SER B 162
PHE B 120
ILE B 210
PHE C 217
 None
 1.01A 3ko0S-3j2jB:
undetectable		 3ko0S-3j2jB:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 3j2j PROTEIN VP2
(Enterovirus
B) 		3 / 3 PRO C  44
THR C  45
LEU C 246
 None
 0.45A 3ttrA-3j2jC:
undetectable		 3ttrA-3j2jC:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3j2j PROTEIN VP2
(Enterovirus
B) 		3 / 3 PHE C 217
VAL C 101
ILE C 232
 None
 0.59A 4emaA-3j2jC:
undetectable		 4emaA-3j2jC:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 3j2j PROTEIN VP1
(Enterovirus
B) 		3 / 3 HIS A 161
TRP A 100
SER A  63
 None
 1.11A 4lrhD-3j2jA:
undetectable		 4lrhD-3j2jA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 3j2j PROTEIN VP1
PROTEIN VP3
(Enterovirus
B) 		4 / 5 PHE A  53
PHE A 123
LEU B  25
PRO A  86
 None
 1.24A 4o8zA-3j2jA:
undetectable		 4o8zA-3j2jA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3j2j PROTEIN VP1
(Enterovirus
B) 		3 / 3 ASP A  97
TYR A  98
TRP A 100
 None
 1.20A 4p7nA-3j2jA:
undetectable		 4p7nA-3j2jA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 3j2j PROTEIN VP2
(Enterovirus
B) 		3 / 3 PRO C 194
MET C 193
TYR C  26
 None
 1.09A 4qa0B-3j2jC:
undetectable		 4qa0B-3j2jC:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3j2j PROTEIN VP2
(Enterovirus
B) 		3 / 3 PRO C 194
MET C 193
TYR C  26
 None
 1.06A 4qa0A-3j2jC:
undetectable		 4qa0A-3j2jC:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3j2j PROTEIN VP1
PROTEIN VP3
PROTEIN VP2
(Enterovirus
B;
Enterovirus
B;
Enterovirus
B) 		5 / 12 HIS C 207
PRO C 119
VAL A 187
ILE B  36
SER C 198
 None
 1.38A 4v2gB-3j2jC:
undetectable		 4v2gB-3j2jC:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 3j2j PROTEIN VP1
PROTEIN VP2
(Enterovirus
B) 		4 / 8 ASN A 132
PHE A 133
PHE A  48
TYR C 176
 None
 1.35A 4v2zC-3j2jA:
undetectable		 4v2zC-3j2jA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 3j2j PROTEIN VP1
PROTEIN VP2
(Enterovirus
B) 		4 / 8 ASN A 139
PHE A 140
TRP A 137
TYR C 208
 None
 1.46A 4v30B-3j2jA:
undetectable		 4v30B-3j2jA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3j2j PROTEIN VP3
(Enterovirus
B) 		5 / 12 PHE B  83
GLY B 188
LEU B  87
VAL B 168
VAL B  55
 None
 0.98A 4wnwA-3j2jB:
undetectable		 4wnwA-3j2jB:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 3j2j PROTEIN VP2
(Enterovirus
B) 		3 / 3 ASP C  48
LEU C   9
GLY C  10
 None
 0.54A 4xmfA-3j2jC:
undetectable		 4xmfA-3j2jC:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3j2j PROTEIN VP3
(Enterovirus
B) 		5 / 12 PHE B 118
VAL B  55
ILE B 132
LEU B 116
LEU B  87
 None
 1.24A 5im2A-3j2jB:
undetectable		 5im2A-3j2jB:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 3j2j PROTEIN VP1
PROTEIN VP3
(Enterovirus
B) 		4 / 7 ILE A  33
LEU B  25
PHE B  28
ARG A  52
 None
 1.01A 5vc0A-3j2jA:
undetectable		 5vc0A-3j2jA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3j2j PROTEIN VP1
PROTEIN VP3
(Enterovirus
B) 		5 / 12 PHE B  13
PHE A 178
ILE A  33
ALA B  24
ALA A 117
 None
 1.20A 5vcgA-3j2jB:
undetectable		 5vcgA-3j2jB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 3j2j PROTEIN VP1
(Enterovirus
B) 		5 / 12 MET A  41
ALA A  10
TYR A 130
VAL A  57
PHE A  59
 None
 1.39A 5vlmD-3j2jA:
undetectable		 5vlmD-3j2jA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3j2j PROTEIN VP1
PROTEIN VP3
(Enterovirus
B;
Enterovirus
B) 		4 / 8 VAL B  94
GLN B  81
ASN A 217
ILE A 216
 None
 0.86A 6hzpA-3j2jB:
undetectable		 6hzpA-3j2jB:
18.61