SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j2n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 ASN U  91
GLY U 342
GLY U 343
ALA U  89
LEU U 194
 None
 0.93A 1bx4A-3j2nU:
undetectable		 1bx4A-3j2nU:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 7 ASP U  87
GLU U 349
GLU U  60
GLU U 381
 None
 1.19A 1knyA-3j2nU:
undetectable
1knyB-3j2nU:
undetectable		 1knyA-3j2nU:
16.61
1knyB-3j2nU:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 ASP U 232
SER U 341
ILE U  95
GLY U 192
GLU U 229
 None
 1.12A 1mehA-3j2nU:
undetectable		 1mehA-3j2nU:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S14_A_NOVA1300_1
(TOPOISOMERASE IV
SUBUNIT B)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLU U 202
ASP U 312
MET U 205
ILE U 193
THR U 326
 None
 1.25A 1s14A-3j2nU:
undetectable		 1s14A-3j2nU:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 GLY U 258
ILE U 150
ILE U  99
GLY U  97
ALA U 152
 None
 1.01A 1sh9B-3j2nU:
undetectable		 1sh9B-3j2nU:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 VAL U 389
VAL U 394
TRP U 359
 None
 0.83A 1w5uA-3j2nU:
undetectable
1w5uB-3j2nU:
undetectable		 1w5uA-3j2nU:
2.37
1w5uB-3j2nU:
2.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 ALA U  96
ASP U 190
ASN U  91
SER U  93
ILE U 198
 None
 1.43A 1xvaB-3j2nU:
2.8		 1xvaB-3j2nU:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 SER U  67
MET U  66
GLY U  31
ALA U 358
ALA U  30
 None
 0.97A 2avdB-3j2nU:
undetectable		 2avdB-3j2nU:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 ASP U 438
ASN U 439
THR U 413
 None
 0.59A 2pymB-3j2nU:
undetectable		 2pymB-3j2nU:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 ASP U 438
ASN U 439
THR U 413
 None
 0.50A 2q63B-3j2nU:
undetectable		 2q63B-3j2nU:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 6 GLU U  47
PHE U  65
GLN U  56
PRO U  57
 None
 1.49A 2qqtA-3j2nU:
undetectable		 2qqtA-3j2nU:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 LYS U  90
ARG U  86
VAL U  84
 None
 1.08A 2r2vC-3j2nU:
undetectable
2r2vD-3j2nU:
undetectable		 2r2vC-3j2nU:
4.63
2r2vD-3j2nU:
4.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 SER U  93
ILE U  95
PHE U 334
THR U 132
GLY U 336
 None
 1.36A 2v0mA-3j2nU:
undetectable		 2v0mA-3j2nU:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 7 SER U  93
PHE U 210
ILE U 193
PRO U 220
GLY U 221
 None
 1.16A 2y7kA-3j2nU:
undetectable		 2y7kA-3j2nU:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 PRO U 331
PHE U 210
LYS U 215
 None
 1.23A 3bjwG-3j2nU:
undetectable		 3bjwG-3j2nU:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLY U 221
ILE U 193
SER U  93
ASN U 329
LEU U 214
 None
 1.39A 3cjtK-3j2nU:
undetectable		 3cjtK-3j2nU:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 11 ASP U 114
ILE U 182
LEU U 178
VAL U 134
ILE U 131
 None
 0.92A 3em4U-3j2nU:
undetectable		 3em4U-3j2nU:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 ASP U 114
ILE U 182
LEU U 178
VAL U 134
ILE U 131
 None
 1.06A 3em4V-3j2nU:
undetectable		 3em4V-3j2nU:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 LEU U 340
ALA U  96
ILE U  95
LEU U 214
PHE U 210
 None
 1.21A 3fl9F-3j2nU:
undetectable		 3fl9F-3j2nU:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 8 TYR U  74
ASP U 473
GLY U 452
SER U 408
 None
 0.87A 3ihzB-3j2nU:
undetectable		 3ihzB-3j2nU:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		6 / 12 GLY U 247
ALA U 267
ALA U 262
ALA U 280
VAL U 239
PRO U 253
 None
 1.41A 3jb2A-3j2nU:
undetectable		 3jb2A-3j2nU:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 6 LEU U  29
VAL U 414
VAL U 468
MET U  66
 None
 1.21A 3k5vB-3j2nU:
undetectable		 3k5vB-3j2nU:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LPS_A_NOVA901_1
(TOPOISOMERASE IV
SUBUNIT B)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLU U 202
ASP U 312
MET U 205
ILE U 193
THR U 326
 None
 1.35A 3lpsA-3j2nU:
undetectable		 3lpsA-3j2nU:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 11 GLN U 390
ALA U 379
ALA U  68
ALA U 472
ASP U 451
 None
 1.03A 3mg0V-3j2nU:
undetectable
3mg0W-3j2nU:
undetectable		 3mg0V-3j2nU:
16.03
3mg0W-3j2nU:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 6 ASN U 425
PRO U 410
LEU U 383
ASP U 438
 None
 1.09A 3oi8A-3j2nU:
undetectable		 3oi8A-3j2nU:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QG2_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 10 ILE U  41
ALA U 358
PHE U 362
SER U 377
ILE U 374
 None
 1.42A 3qg2A-3j2nU:
undetectable		 3qg2A-3j2nU:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUM_A_CCSA375_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 4 GLN U 278
SER U 277
GLY U 301
LYS U 298
 None
 1.14A 3rumA-3j2nU:
0.0		 3rumA-3j2nU:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 5 ILE U 143
ILE U  99
TYR U 101
GLU U 100
 None
 1.24A 4a99D-3j2nU:
undetectable		 4a99D-3j2nU:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 PHE U 362
ASP U 369
ARG U  79
 None
 0.89A 4eahF-3j2nU:
1.2		 4eahF-3j2nU:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 PHE U 362
ASP U 369
ARG U  79
 None
 0.89A 4eahG-3j2nU:
undetectable		 4eahG-3j2nU:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 5 SER U 108
GLY U 138
THR U 105
ASP U 135
 None
 1.13A 4eohA-3j2nU:
4.6		 4eohA-3j2nU:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 ILE U 474
ALA U 472
LEU U 505
ILE U 499
TYR U  74
 None
 1.08A 4m2xE-3j2nU:
undetectable		 4m2xE-3j2nU:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 8 ASP U 364
VAL U 370
SER U 367
ALA U  28
 None
 0.91A 4m48A-3j2nU:
undetectable		 4m48A-3j2nU:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 6 PHE U 373
ILE U 396
ARG U 400
VAL U 368
 None
 1.42A 4mk4B-3j2nU:
undetectable		 4mk4B-3j2nU:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 11 ILE U 474
ALA U 472
LEU U 505
ILE U 499
TYR U  74
 None
 1.14A 4p66A-3j2nU:
undetectable		 4p66A-3j2nU:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 ILE U 474
ALA U 472
LEU U 505
ILE U 499
TYR U  74
 None
 1.09A 4pthA-3j2nU:
undetectable		 4pthA-3j2nU:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 9 ALA U 475
ALA U 471
ALA U 375
SER U 377
ALA U  27
 None
 1.26A 4twdA-3j2nU:
undetectable
4twdB-3j2nU:
undetectable
4twdC-3j2nU:
undetectable
4twdD-3j2nU:
undetectable
4twdE-3j2nU:
undetectable		 4twdA-3j2nU:
18.44
4twdB-3j2nU:
18.44
4twdC-3j2nU:
18.44
4twdD-3j2nU:
18.44
4twdE-3j2nU:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 8 ALA U  27
ALA U 475
ALA U 471
ALA U 375
SER U 377
 None
 1.30A 4twdF-3j2nU:
0.8
4twdG-3j2nU:
0.1
4twdH-3j2nU:
0.1
4twdI-3j2nU:
undetectable
4twdJ-3j2nU:
undetectable		 4twdF-3j2nU:
18.44
4twdG-3j2nU:
18.44
4twdH-3j2nU:
18.44
4twdI-3j2nU:
18.44
4twdJ-3j2nU:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 8 ALA U 475
ALA U 471
ALA U 375
SER U 377
ALA U  27
 None
 1.22A 4twdF-3j2nU:
0.8
4twdG-3j2nU:
0.1
4twdH-3j2nU:
0.1
4twdI-3j2nU:
undetectable
4twdJ-3j2nU:
undetectable		 4twdF-3j2nU:
18.44
4twdG-3j2nU:
18.44
4twdH-3j2nU:
18.44
4twdI-3j2nU:
18.44
4twdJ-3j2nU:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 11 GLU U 202
ASP U 312
MET U 205
ILE U 193
THR U 326
 None
 1.46A 4urnB-3j2nU:
undetectable		 4urnB-3j2nU:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 11 GLU U 202
ASP U 312
MET U 205
ILE U 193
THR U 326
 None
 1.50A 4urnC-3j2nU:
undetectable		 4urnC-3j2nU:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 4 PHE U  33
VAL U  80
ALA U  30
PHE U 362
 None
 1.32A 4w5qA-3j2nU:
undetectable		 4w5qA-3j2nU:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 THR U 147
ASN U 144
GLU U 100
ILE U 187
ILE U  95
 None
 1.27A 4zvmA-3j2nU:
3.0
4zvmB-3j2nU:
3.5		 4zvmA-3j2nU:
15.58
4zvmB-3j2nU:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 ALA U 422
ASN U 425
LEU U 426
 None
 0.49A 5i1oA-3j2nU:
undetectable		 5i1oA-3j2nU:
4.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR U 297
SER U 296
TYR U 279
 None
 0.89A 5jseA-3j2nU:
undetectable		 5jseA-3j2nU:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		3 / 3 THR U 297
SER U 296
TYR U 279
 None
 0.88A 5jseB-3j2nU:
undetectable		 5jseB-3j2nU:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 6 ILE U 374
ARG U  79
THR U  45
LEU U  72
 None
 1.02A 5z86N-3j2nU:
undetectable
5z86W-3j2nU:
undetectable		 5z86N-3j2nU:
21.98
5z86W-3j2nU:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		4 / 6 ILE U 374
ARG U  79
THR U  45
LEU U  72
 None
 1.03A 5zcoN-3j2nU:
undetectable
5zcoW-3j2nU:
undetectable		 5zcoN-3j2nU:
21.98
5zcoW-3j2nU:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 VAL U 370
ASP U 369
ALA U  27
PHE U  71
LEU U  72
 None
 1.11A 6ew0G-3j2nU:
3.7		 6ew0G-3j2nU:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3j2n TAIL SHEATH PROTEIN
GP18
(Escherichia
virus
T4) 		5 / 12 GLN U 390
ALA U 379
ALA U  68
ALA U 472
ASP U 451
 None
 1.03A 6hwdH-3j2nU:
undetectable
6hwdI-3j2nU:
undetectable		 6hwdH-3j2nU:
8.50
6hwdI-3j2nU:
8.06