SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3j2v PREC/CORE PROTEIN
(Hepatitis
B
virus) 		5 / 12 GLY C  10
ASP C   4
PHE C   9
LEU C  16
LEU C 119
 None
 1.13A 1lhuA-3j2vC:
undetectable		 1lhuA-3j2vC:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 3j2v PREC/CORE PROTEIN
(Hepatitis
B
virus) 		4 / 8 TYR C   6
LEU C 116
VAL C 115
LEU C 119
 None
 0.71A 2w98B-3j2vC:
undetectable		 2w98B-3j2vC:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB8_A_IMNA800_1
(PROSTAGLANDIN
REDUCTASE 2)		 3j2v PREC/CORE PROTEIN
(Hepatitis
B
virus) 		5 / 9 TYR C   6
PHE C  24
LEU C 116
VAL C 115
LEU C 119
 None
 1.36A 2zb8A-3j2vC:
undetectable		 2zb8A-3j2vC:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3j2v PREC/CORE PROTEIN
(Hepatitis
B
virus) 		4 / 8 PHE C  24
SER C 106
PHE C  23
LEU C  16
 None
 0.98A 5y2tB-3j2vC:
undetectable		 5y2tB-3j2vC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 3j2v PREC/CORE PROTEIN
(Hepatitis
B
virus) 		4 / 6 GLU C  46
ARG C  56
GLU C  43
ALA C  41
 None
 1.21A 6an0A-3j2vC:
undetectable		 6an0A-3j2vC:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3j2v PREC/CORE PROTEIN
(Hepatitis
B
virus) 		3 / 3 PHE C  24
ARG C  98
GLN C  99
 None
 1.03A 6g1pB-3j2vC:
undetectable		 6g1pB-3j2vC:
19.48