SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3j3r ADAPTER PROTEIN MECA
1
(Bacillus
subtilis) 		5 / 11 LEU 1 127
LEU 1 179
VAL 1 175
TYR 1 164
GLN 1 128
 None
 1.43A 1kt7A-3j3r1:
undetectable		 1kt7A-3j3r1:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3j3r ADAPTER PROTEIN MECA
1
(Bacillus
subtilis) 		4 / 7 THR 1 152
LEU 1 131
LEU 1 142
LEU 1 182
 None
 0.91A 3bgdB-3j3r1:
undetectable		 3bgdB-3j3r1:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3j3r ADAPTER PROTEIN MECA
1
(Bacillus
subtilis) 		5 / 10 TYR 1 161
ILE 1 212
ILE 1 204
VAL 1 139
TYR 1 155
 None
 1.31A 5mvnD-3j3r1:
undetectable		 5mvnD-3j3r1:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3j3r ADAPTER PROTEIN MECA
1
(Bacillus
subtilis) 		5 / 12 GLY 1 149
SER 1 150
ASN 1 177
LEU 1 179
LEU 1 182
 None
 1.17A 5nwwA-3j3r1:
undetectable		 5nwwA-3j3r1:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 3j3r ADAPTER PROTEIN MECA
1
(Bacillus
subtilis) 		4 / 5 ALA 1 186
TYR 1 185
GLN 1 178
ILE 1 181
 None
 1.32A 6g9bA-3j3r1:
undetectable
6g9bB-3j3r1:
undetectable		 6g9bA-3j3r1:
18.57
6g9bB-3j3r1:
15.38