SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j3w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3j3w 50S RIBOSOMAL
PROTEIN L15
(Bacillus
subtilis) 		5 / 12 ALA L 132
THR L 142
ILE L 111
GLY L 140
ALA L 135
 None
 1.02A 1utdL-3j3wL:
undetectable
1utdM-3j3wL:
undetectable		 1utdL-3j3wL:
19.40
1utdM-3j3wL:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3j3w 50S RIBOSOMAL
PROTEIN L15
(Bacillus
subtilis) 		5 / 12 ALA L 132
THR L 142
ILE L 111
GLY L 140
ALA L 135
 None
 1.02A 1utdO-3j3wL:
undetectable
1utdP-3j3wL:
undetectable		 1utdO-3j3wL:
19.40
1utdP-3j3wL:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3j3w 50S RIBOSOMAL
PROTEIN L15
(Bacillus
subtilis) 		5 / 11 ALA L 132
THR L 142
ILE L 111
GLY L 140
ALA L 135
 None
 1.02A 1utdP-3j3wL:
undetectable
1utdQ-3j3wL:
undetectable		 1utdP-3j3wL:
19.40
1utdQ-3j3wL:
19.40