SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j40'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 3j40 GP10
(Salmonella
virus
Epsilon15) 		5 / 10 ALA N  97
ASP N  96
ASP N  95
GLY N  15
PRO N  91
 None
 1.18A 1d4sA-3j40N:
undetectable		 1d4sA-3j40N:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		4 / 5 ILE A  14
ARG A  17
ARG A  26
ASP A  19
 None
 1.31A 2rhmB-3j40A:
undetectable		 2rhmB-3j40A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		4 / 5 SER A 229
ARG A 231
GLY A 181
TRP A 180
 None
 0.90A 2y7kB-3j40A:
undetectable		 2y7kB-3j40A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		4 / 6 SER A 229
ARG A 231
GLY A 181
TRP A 180
 None
 0.79A 2y7pA-3j40A:
undetectable		 2y7pA-3j40A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		3 / 3 SER A  50
ASP A  48
ASP A  84
 None
 0.90A 3iv6A-3j40A:
undetectable		 3iv6A-3j40A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		4 / 6 ILE A  37
ALA A  41
THR A  39
VAL A 125
 None
 0.91A 5eclD-3j40A:
undetectable		 5eclD-3j40A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		4 / 8 ILE A  37
ALA A  41
THR A  39
VAL A 125
 None
 0.86A 5ecnD-3j40A:
undetectable		 5ecnD-3j40A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		5 / 10 ALA A 185
THR A 184
CYH A  46
GLY A  87
ASP A  84
 None
 1.14A 5lf3H-3j40A:
undetectable
5lf3I-3j40A:
undetectable		 5lf3H-3j40A:
22.51
5lf3I-3j40A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		5 / 11 ALA A 185
THR A 184
CYH A  46
GLY A  87
ASP A  84
 None
 1.08A 5lf7H-3j40A:
undetectable
5lf7I-3j40A:
undetectable		 5lf7H-3j40A:
22.51
5lf7I-3j40A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		5 / 11 ALA A 185
THR A 184
CYH A  46
GLY A  87
ASP A  84
 None
 1.05A 5lf7V-3j40A:
undetectable
5lf7W-3j40A:
undetectable		 5lf7V-3j40A:
22.51
5lf7W-3j40A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		5 / 7 ASP A 220
ARG A 219
TYR A 218
GLU A 200
ASP A 201
 None
 1.42A 6mn5B-3j40A:
undetectable		 6mn5B-3j40A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3j40 GP7
(Salmonella
virus
Epsilon15) 		4 / 6 ASP A 220
TYR A 218
GLU A 200
ASP A 201
 None
 1.30A 6mn5C-3j40A:
undetectable		 6mn5C-3j40A:
12.39