SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 LEU A 275
TRP A 235
TYR A 245
 None
 0.95A 3aicA-3j6dA:
undetectable		 3aicA-3j6dA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 LEU A 275
TRP A 235
TYR A 245
 None
 0.95A 3aicB-3j6dA:
undetectable		 3aicB-3j6dA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 LEU A 275
TRP A 235
TYR A 245
 None
 0.94A 3aicE-3j6dA:
undetectable		 3aicE-3j6dA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 LEU A 275
TRP A 235
TYR A 245
 None
 0.92A 3aicF-3j6dA:
undetectable		 3aicF-3j6dA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 LEU A 275
TRP A 235
TYR A 245
 None
 0.95A 3aicG-3j6dA:
undetectable		 3aicG-3j6dA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		3 / 3 LEU A 275
TRP A 235
TYR A 245
 None
 0.95A 3aicH-3j6dA:
undetectable		 3aicH-3j6dA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		4 / 5 LEU A 307
GLY A 306
PHE A 342
PHE A 357
 None
 1.09A 3smtA-3j6dA:
undetectable		 3smtA-3j6dA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		4 / 7 TRP A 206
VAL A 210
VAL A 186
PHE A 184
 None
 0.80A 3zjqA-3j6dA:
undetectable		 3zjqA-3j6dA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		4 / 7 TRP A 206
VAL A 210
VAL A 186
PHE A 184
 None
 0.76A 3zjqB-3j6dA:
undetectable		 3zjqB-3j6dA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		5 / 12 ARG A 231
ILE A 232
ASN A 229
PHE A 258
HIS A 249
 None
 1.33A 4c49D-3j6dA:
undetectable		 4c49D-3j6dA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		4 / 6 SER A 315
GLY A 329
GLU A 360
ASP A 332
 None
 0.97A 4uckB-3j6dA:
undetectable		 4uckB-3j6dA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3j6d PROTEIN PRGH
(Salmonella
enterica) 		5 / 10 ALA A 281
LEU A 282
LEU A 236
VAL A 289
ILE A 248
 None
 1.02A 5v02B-3j6dA:
undetectable
5v02R-3j6dA:
undetectable		 5v02B-3j6dA:
15.64
5v02R-3j6dA:
16.88