SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3j7e H16.V5 FAB LIGHT
CHAIN
(Mus
musculus) 		4 / 6 LEU L 110
VAL L  19
VAL L  15
GLN L  85
 None
 0.89A 1e7aB-3j7eL:
undetectable		 1e7aB-3j7eL:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3j7e H16.V5 FAB LIGHT
CHAIN
(Mus
musculus) 		4 / 5 GLY L  70
LEU L  79
THR L  78
VAL L  54
 None
 1.09A 1ekjF-3j7eL:
undetectable
1ekjG-3j7eL:
undetectable		 1ekjF-3j7eL:
19.13
1ekjG-3j7eL:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3j7e H16.V5 FAB LIGHT
CHAIN
(Mus
musculus) 		3 / 3 PHE L  77
TYR L  98
LEU L  53
 None
 0.79A 3keeB-3j7eL:
undetectable		 3keeB-3j7eL:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 3j7e H16.V5 FAB LIGHT
CHAIN
(Mus
musculus) 		4 / 5 ASN L  37
LEU L  39
SER L  58
LEU L  79
 None
 1.20A 4n09C-3j7eL:
undetectable		 4n09C-3j7eL:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j7e H16.V5 FAB LIGHT
CHAIN
(Mus
musculus) 		4 / 6 GLN L  95
PHE L  93
LEU L  79
PHE L  68
 None
 1.13A 5zcpP-3j7eL:
undetectable
5zcpW-3j7eL:
undetectable		 5zcpP-3j7eL:
19.84
5zcpW-3j7eL:
18.58