SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j83'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 7 LEU A 270
VAL A 212
VAL A  32
ILE A  34
 None
 0.76A 1t87B-3j83A:
undetectable		 1t87B-3j83A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 5 PRO A 275
VAL A 273
THR A 158
GLY A 155
 None
 1.20A 3elzB-3j83A:
undetectable		 3elzB-3j83A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 8 LEU A 270
VAL A 212
VAL A  32
ILE A  34
 None
 0.80A 4l4cB-3j83A:
undetectable		 4l4cB-3j83A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 7 THR A  40
ALA A 125
THR A 124
ALA A 123
 None
 0.94A 4qw0K-3j83A:
undetectable		 4qw0K-3j83A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 7 THR A  40
ALA A 125
THR A 124
ALA A 123
 None
 0.95A 4qw0Y-3j83A:
undetectable		 4qw0Y-3j83A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 7 ALA A  77
GLY A 178
ALA A 181
SER A 187
 None
 0.80A 4r1zB-3j83A:
undetectable		 4r1zB-3j83A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB
(Mycobacterium
tuberculosis) 		4 / 6 TRP A 156
MET A  25
GLY A 165
ALA A 199
 None
 0.78A 6fosA-3j83A:
undetectable		 6fosA-3j83A:
13.71