SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j8f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		5 / 7 LEU 7  92
ARG 7  91
LEU 7  47
LEU 7 113
GLY 7 112
 None
 1.38A 1n13D-3j8f7:
undetectable
1n13E-3j8f7:
undetectable		 1n13D-3j8f7:
15.72
1n13E-3j8f7:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		5 / 7 LEU 7  92
LEU 7 139
GLY 7 119
MET 7  75
GLU 7  88
 None
None
NAG  7 504 ( 3.9A)
None
None
 1.42A 1n13G-3j8f7:
undetectable
1n13J-3j8f7:
undetectable		 1n13G-3j8f7:
10.05
1n13J-3j8f7:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 504 ( 1.8A)
None
NAG  7 504 ( 3.9A)
 0.95A 1ykiA-3j8f7:
undetectable
1ykiB-3j8f7:
undetectable		 1ykiA-3j8f7:
17.38
1ykiB-3j8f7:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 504 ( 1.8A)
None
NAG  7 504 ( 3.9A)
 0.95A 1ykiA-3j8f7:
undetectable
1ykiB-3j8f7:
undetectable		 1ykiA-3j8f7:
17.38
1ykiB-3j8f7:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 504 ( 1.8A)
None
NAG  7 504 ( 3.9A)
 0.90A 1ykiC-3j8f7:
undetectable
1ykiD-3j8f7:
undetectable		 1ykiC-3j8f7:
17.38
1ykiD-3j8f7:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 504 ( 1.8A)
None
NAG  7 504 ( 3.9A)
 0.91A 1ykiC-3j8f7:
undetectable
1ykiD-3j8f7:
undetectable		 1ykiC-3j8f7:
17.38
1ykiD-3j8f7:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 PRO 7 173
ARG 7 172
GLU 7 226
 None
 0.96A 5j6hA-3j8f7:
9.3		 5j6hA-3j8f7:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 GLY 7 216
THR 7 239
ASN 7 237
 NAG  7 513 (-3.8A)
None
NAG  7 513 (-1.9A)
 0.59A 5odiG-3j8f7:
undetectable		 5odiG-3j8f7:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3j8f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 ALA 7 175
PHE 7 228
GLN 7 232
 None
 0.71A 6eceA-3j8f7:
undetectable		 6eceA-3j8f7:
20.82