SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j8v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 3j8v H16.14J HEAVY CHAIN
H16.14J LIGHT CHAIN
(Mus
musculus) 		8 / 12 TYR L  36
GLN L  89
LEU L  96
PHE L  98
ASN H  35
VAL H  37
ALA H  93
TRP H 103
 None
 0.66A 1h8sA-3j8vL:
22.2		 1h8sA-3j8vL:
49.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.01A 1usqA-3j8vH:
undetectable		 1usqA-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqB-3j8vH:
undetectable		 1usqB-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqC-3j8vH:
undetectable		 1usqC-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqD-3j8vH:
undetectable		 1usqD-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.80A 1usqE-3j8vH:
1.9		 1usqE-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.00A 1usqF-3j8vH:
2.0		 1usqF-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.86A 2jkjA-3j8vH:
undetectable		 2jkjA-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.86A 2jkjB-3j8vH:
undetectable		 2jkjB-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.86A 2jkjC-3j8vH:
undetectable		 2jkjC-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.03A 2jkjE-3j8vH:
undetectable		 2jkjE-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.04A 2jklA-3j8vH:
undetectable		 2jklA-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H  53
PRO H  52
ILE H  51
GLY H  55
 None
 0.86A 2jklB-3j8vH:
undetectable		 2jklB-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.04A 2jklC-3j8vH:
undetectable		 2jklC-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.03A 2jklD-3j8vH:
undetectable		 2jklD-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.04A 2jklE-3j8vH:
undetectable		 2jklE-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		5 / 7 GLY H  53
PRO H  52
THR H  57
ILE H  51
GLY H  55
 None
 1.04A 2jklF-3j8vH:
undetectable		 2jklF-3j8vH:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3j8v H16.14J HEAVY CHAIN
H16.14J LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		3 / 3 ASN L  42
MET H 100
PHE H  91
 None
 1.02A 3g4lD-3j8vL:
undetectable		 3g4lD-3j8vL:
13.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3j8v H16.14J LIGHT CHAIN
(Mus
musculus) 		4 / 5 TYR L  36
GLN L  89
LEU L  96
PHE L  98
 None
 0.50A 3ls4L-3j8vL:
21.0		 3ls4L-3j8vL:
61.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFE_C_TMGC1_1
(SUCCINATE
DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR SUBUNIT,
MITOCHONDRIAL
SUCCINATE
DEHYDROGENASE
CYTOCHROME B560
SUBUNIT,
MITOCHONDRIAL)		 3j8v H16.14J HEAVY CHAIN
(Mus
musculus) 		4 / 8 ILE H  82
TRP H  36
MET H  80
ILE H  20
 None
 1.03A 3sfeB-3j8vH:
undetectable
3sfeC-3j8vH:
undetectable		 3sfeB-3j8vH:
18.33
3sfeC-3j8vH:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 3j8v H16.14J LIGHT CHAIN
(Mus
musculus) 		4 / 6 CYH L  23
THR L  22
CYH L  88
ILE L  29
 None
 1.25A 3w9tB-3j8vL:
undetectable		 3w9tB-3j8vL:
14.01