SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3j93 NEUTRALIZING
ANTIBODY 22A12,
HEAVY CHAIN
(Mus
musculus) 		4 / 6 GLY H 119
PRO H  12
LYS H  11
THR H 116
 None
 1.23A 2m2oB-3j93H:
undetectable		 2m2oB-3j93H:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3j93 NEUTRALIZING
ANTIBODY 22A12,
HEAVY CHAIN
(Mus
musculus) 		4 / 7 VAL H 143
GLY H 140
ALA H 139
SER H 191
 None
 0.92A 2wekB-3j93H:
undetectable		 2wekB-3j93H:
22.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3j93 NEUTRALIZING
ANTIBODY 22A12,
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  97
TYR H 108
 None
 0.39A 4m7kH-3j93H:
16.6		 4m7kH-3j93H:
65.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3j93 NEUTRALIZING
ANTIBODY 22A12,
HEAVY CHAIN
(Mus
musculus) 		3 / 3 TRP H  47
GLU H  46
GLU H  62
 None
 1.02A 6fhwA-3j93H:
2.9		 6fhwA-3j93H:
20.10