SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
3 / 3 SER H 157
GLU H 156
GLU H 155
None
0.34A 1eqbD-3j97H:
undetectable
1eqbD-3j97H:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
3 / 3 SER H 157
GLU H 156
GLU H 155
None
0.34A 1eqbB-3j97H:
undetectable
1eqbB-3j97H:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 9 VAL A 391
GLY A 255
ALA A 234
ILE A 256
SER A 237
None
1.32A 1gtnL-3j97A:
undetectable
1gtnM-3j97A:
undetectable
1gtnL-3j97A:
7.26
1gtnM-3j97A:
7.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 6 ALA A 584
LYS A 587
ASP A 591
ALA A 592
LEU A 640
None
1.28A 1iwhA-3j97A:
undetectable
1iwhA-3j97A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 11 PHE A 125
ASN A 180
LEU A 176
GLY A 175
PHE A 130
None
1.29A 1ju6A-3j97A:
undetectable
1ju6A-3j97A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 11 LEU A 608
ALA A 580
VAL A 602
MET A 585
LEU A 629
None
1.37A 1kt7A-3j97A:
undetectable
1kt7A-3j97A:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 8 PHE A 140
LEU A 147
GLY A 146
PHE A 145
None
0.68A 1rtsA-3j97A:
undetectable
1rtsA-3j97A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 11 VAL A  60
ALA A  61
PHE A  62
LEU A  72
ILE A  74
None
1.28A 1uduA-3j97A:
undetectable
1uduA-3j97A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 1v54A-3j97H:
2.9
1v54C-3j97H:
5.0
1v54A-3j97H:
19.26
1v54C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.22A 1v54N-3j97H:
2.8
1v54P-3j97H:
5.0
1v54N-3j97H:
19.26
1v54P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 1v55A-3j97H:
2.8
1v55C-3j97H:
5.0
1v55A-3j97H:
19.26
1v55C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 LEU A 541
LEU A 552
ILE A 665
GLU A 522
LEU A 518
None
1.25A 1wopA-3j97A:
undetectable
1wopA-3j97A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2dyrA-3j97H:
2.8
2dyrC-3j97H:
5.1
2dyrA-3j97H:
19.26
2dyrC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2dyrN-3j97H:
2.8
2dyrP-3j97H:
5.0
2dyrN-3j97H:
19.26
2dyrP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.25A 2dysA-3j97H:
2.7
2dysC-3j97H:
5.1
2dysA-3j97H:
19.26
2dysC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.22A 2dysN-3j97H:
2.7
2dysP-3j97H:
5.1
2dysN-3j97H:
19.26
2dysP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2eijA-3j97H:
2.8
2eijC-3j97H:
5.0
2eijA-3j97H:
19.26
2eijC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2eijN-3j97H:
2.8
2eijP-3j97H:
5.0
2eijN-3j97H:
19.26
2eijP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.27A 2eikA-3j97H:
undetectable
2eikC-3j97H:
5.0
2eikA-3j97H:
19.26
2eikC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 2eikN-3j97H:
2.8
2eikP-3j97H:
5.0
2eikN-3j97H:
19.26
2eikP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2eilA-3j97H:
2.7
2eilC-3j97H:
5.0
2eilA-3j97H:
19.26
2eilC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 2eilN-3j97H:
2.8
2eilP-3j97H:
5.0
2eilN-3j97H:
19.26
2eilP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.25A 2eimA-3j97H:
3.4
2eimC-3j97H:
5.1
2eimA-3j97H:
19.26
2eimC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.30A 2eimN-3j97H:
3.2
2eimP-3j97H:
5.0
2eimN-3j97H:
19.26
2eimP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2einA-3j97H:
2.4
2einC-3j97H:
5.0
2einA-3j97H:
19.26
2einC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.28A 2einN-3j97H:
2.8
2einP-3j97H:
5.1
2einN-3j97H:
19.26
2einP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 4 VAL A 350
THR A 349
VAL A 295
GLY A 296
None
1.12A 2p2fB-3j97A:
undetectable
2p2fB-3j97A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
3 / 3 VAL H 256
ASP H 257
GLU H 291
None
0.50A 2qeuA-3j97H:
3.5
2qeuA-3j97H:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
3 / 3 VAL H 256
ASP H 257
GLU H 291
None
0.52A 2qeuC-3j97H:
3.5
2qeuC-3j97H:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
3 / 3 SER A 569
THR A 550
PHE A 661
None
0.74A 2x91A-3j97A:
undetectable
2x91A-3j97A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 8 ILE A 643
TYR A 502
VAL A 602
CYH A 599
None
1.18A 2xz5A-3j97A:
undetectable
2xz5C-3j97A:
undetectable
2xz5A-3j97A:
14.13
2xz5C-3j97A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 8 ILE A 643
TYR A 502
VAL A 602
CYH A 599
None
1.17A 2xz5C-3j97A:
undetectable
2xz5D-3j97A:
undetectable
2xz5C-3j97A:
14.13
2xz5D-3j97A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 7 ILE A 643
TYR A 502
VAL A 602
CYH A 599
None
1.19A 2xz5D-3j97A:
undetectable
2xz5E-3j97A:
undetectable
2xz5D-3j97A:
14.13
2xz5E-3j97A:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 ILE H 125
SER H 157
TYR H 151
CYH H 164
None
1.29A 2xz5D-3j97H:
undetectable
2xz5E-3j97H:
undetectable
2xz5D-3j97H:
21.23
2xz5E-3j97H:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 2y69A-3j97H:
2.8
2y69C-3j97H:
5.1
2y69A-3j97H:
19.26
2y69C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.21A 2zxwA-3j97H:
2.8
2zxwC-3j97H:
5.0
2zxwA-3j97H:
19.26
2zxwC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.22A 2zxwN-3j97H:
3.7
2zxwP-3j97H:
5.0
2zxwN-3j97H:
19.26
2zxwP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 3abkA-3j97H:
2.9
3abkC-3j97H:
5.0
3abkA-3j97H:
19.26
3abkC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.27A 3abkN-3j97H:
2.3
3abkP-3j97H:
5.0
3abkN-3j97H:
19.26
3abkP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.22A 3abmN-3j97H:
2.9
3abmP-3j97H:
5.0
3abmN-3j97H:
19.26
3abmP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.27A 3ag1A-3j97H:
3.2
3ag1C-3j97H:
4.9
3ag1A-3j97H:
19.26
3ag1C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.26A 3ag1N-3j97H:
2.7
3ag1P-3j97H:
5.0
3ag1N-3j97H:
19.26
3ag1P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.26A 3ag2A-3j97H:
2.8
3ag2C-3j97H:
5.0
3ag2A-3j97H:
19.26
3ag2C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.25A 3ag2N-3j97H:
3.4
3ag2P-3j97H:
5.0
3ag2N-3j97H:
19.26
3ag2P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.28A 3ag3A-3j97H:
3.3
3ag3C-3j97H:
5.0
3ag3A-3j97H:
19.26
3ag3C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 3ag3N-3j97H:
2.8
3ag3P-3j97H:
5.0
3ag3N-3j97H:
19.26
3ag3P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.26A 3ag4A-3j97H:
undetectable
3ag4C-3j97H:
5.0
3ag4A-3j97H:
19.26
3ag4C-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.28A 3ag4N-3j97H:
2.8
3ag4P-3j97H:
5.0
3ag4N-3j97H:
19.26
3ag4P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.26A 3asnA-3j97H:
2.9
3asnC-3j97H:
5.0
3asnA-3j97H:
19.26
3asnC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
5 / 11 GLU H 186
GLY H 189
ILE H 184
ALA H 169
ASP H 204
None
0.97A 3dxyA-3j97H:
undetectable
3dxyA-3j97H:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gB-3j97A:
undetectable
3j6gB-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gD-3j97A:
undetectable
3j6gD-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gF-3j97A:
undetectable
3j6gF-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gH-3j97A:
1.3
3j6gH-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gJ-3j97A:
1.8
3j6gJ-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gL-3j97A:
1.2
3j6gL-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gN-3j97A:
undetectable
3j6gN-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gP-3j97A:
1.2
3j6gP-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 10 ASP A  14
LEU A 136
SER A 139
PHE A 125
THR A  48
None
1.49A 3j6gR-3j97A:
undetectable
3j6gR-3j97A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 6 VAL A 514
LEU A 641
ILE A 567
LEU A 518
None
0.72A 3kk6A-3j97A:
undetectable
3kk6A-3j97A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
3 / 3 LEU A 710
TRP A 510
GLY A 511
None
0.76A 3l35A-3j97A:
undetectable
3l35H-3j97A:
undetectable
3l35A-3j97A:
5.50
3l35H-3j97A:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
3 / 3 LEU A 710
TRP A 510
GLY A 511
None
0.81A 3l35B-3j97A:
undetectable
3l35K-3j97A:
undetectable
3l35B-3j97A:
5.50
3l35K-3j97A:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 8 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 3wg7C-3j97H:
5.0
3wg7N-3j97H:
2.8
3wg7P-3j97H:
5.0
3wg7C-3j97H:
19.54
3wg7N-3j97H:
19.26
3wg7P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 12 ASP A 328
PHE A 327
LEU A 354
VAL A 369
THR A 267
None
0.91A 4eckB-3j97A:
undetectable
4eckB-3j97A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 7 THR A 534
VAL A 628
SER A 662
ASP A 590
None
1.29A 4iarA-3j97A:
undetectable
4iarA-3j97A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 5b1aN-3j97H:
2.8
5b1aP-3j97H:
5.0
5b1aN-3j97H:
19.26
5b1aP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.25A 5b1bN-3j97H:
3.6
5b1bP-3j97H:
5.1
5b1bN-3j97H:
19.26
5b1bP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 5b3sN-3j97H:
2.8
5b3sP-3j97H:
5.0
5b3sN-3j97H:
19.26
5b3sP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 7 PHE A 140
LEU A 147
GLY A 146
PHE A 145
None
0.64A 5h3aB-3j97A:
undetectable
5h3aB-3j97A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.20A 5iy5A-3j97H:
2.8
5iy5C-3j97H:
5.0
5iy5A-3j97H:
19.26
5iy5C-3j97H:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 ILE H 125
GLY H  89
ASN H  90
ILE H 127
None
0.95A 5j4nB-3j97H:
undetectable
5j4nB-3j97H:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 12 GLY A 543
VAL A 517
THR A 515
ALA A 551
LEU A 552
None
1.04A 5kocA-3j97A:
2.2
5kocA-3j97A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NVP_A_ACAA18_1
(ENVELOPE
GLYCOPROTEIN,GP41)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
5 / 12 SER H 238
LYS H 242
LYS H 203
GLU H 229
GLU H 230
None
1.45A 5nvpA-3j97H:
0.0
5nvpA-3j97H:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
5 / 12 LEU A  16
SER A  25
VAL A  23
ALA A   9
ALA A  61
None
1.16A 5tzoB-3j97A:
undetectable
5tzoB-3j97A:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 5x19N-3j97H:
0.7
5x19P-3j97H:
4.9
5x19N-3j97H:
19.26
5x19P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.21A 5x1bN-3j97H:
2.7
5x1bP-3j97H:
4.8
5x1bN-3j97H:
19.26
5x1bP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.25A 5x1fN-3j97H:
2.8
5x1fP-3j97H:
4.9
5x1fN-3j97H:
19.26
5x1fP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 7 PHE A 140
LEU A 147
GLY A 146
PHE A 145
None
0.62A 5x5qC-3j97A:
undetectable
5x5qC-3j97A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 8 PHE A 140
LEU A 147
GLY A 146
PHE A 145
None
0.64A 5x5qD-3j97A:
undetectable
5x5qD-3j97A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)
3j97 VESICLE-FUSING
ATPASE

(Cricetulus
griseus)
4 / 8 PHE A 140
LEU A 147
GLY A 146
PHE A 145
None
0.63A 5x5qF-3j97A:
undetectable
5x5qF-3j97A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 8 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.22A 5z84A-3j97H:
2.8
5z84C-3j97H:
5.1
5z84P-3j97H:
5.1
5z84A-3j97H:
19.26
5z84C-3j97H:
19.54
5z84P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.22A 5z84C-3j97H:
5.1
5z84N-3j97H:
2.8
5z84P-3j97H:
5.1
5z84C-3j97H:
19.54
5z84N-3j97H:
19.26
5z84P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 5z85C-3j97H:
5.0
5z85N-3j97H:
2.9
5z85P-3j97H:
5.1
5z85C-3j97H:
19.54
5z85N-3j97H:
19.26
5z85P-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 8 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 5zcoA-3j97H:
2.8
5zcoC-3j97H:
5.1
5zcoP-3j97H:
5.1
5zcoA-3j97H:
19.26
5zcoC-3j97H:
19.54
5zcoP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 5zcqN-3j97H:
2.8
5zcqP-3j97H:
5.1
5zcqN-3j97H:
19.26
5zcqP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 8 ASP H  80
HIS H 123
HIS H  72
ASP H  87
None
1.11A 6mn4B-3j97H:
undetectable
6mn4B-3j97H:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 8 ASP H  80
HIS H 123
HIS H  72
ASP H  87
None
1.07A 6mn4C-3j97H:
undetectable
6mn4C-3j97H:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.23A 6nknA-3j97H:
2.9
6nknC-3j97H:
4.8
6nknA-3j97H:
19.26
6nknC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 6nmfN-3j97H:
undetectable
6nmfP-3j97H:
4.9
6nmfN-3j97H:
19.26
6nmfP-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 6 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.21A 6nmpA-3j97H:
2.8
6nmpC-3j97H:
4.8
6nmpA-3j97H:
19.26
6nmpC-3j97H:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
3j97 ALPHA-SOLUBLE NSF
ATTACHMENT PROTEIN

(Rattus
norvegicus)
4 / 7 HIS H 124
ASP H 113
THR H 112
HIS H 144
None
1.24A 6nmpN-3j97H:
1.6
6nmpP-3j97H:
5.0
6nmpN-3j97H:
19.26
6nmpP-3j97H:
19.54