SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 ASP A 415
ASP A 543
ASP A 571
 None
 0.75A 1eizA-3j9dA:
undetectable		 1eizA-3j9dA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 ASP A 415
ASP A 543
ASP A 571
 None
 0.78A 1ej0A-3j9dA:
undetectable		 1ej0A-3j9dA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 CYH A 162
ASP A 157
CYH A 851
GLY A 852
 ZN  A1001 (-2.3A)
None
ZN  A1001 (-2.7A)
None
 0.85A 1ekjA-3j9dA:
undetectable
1ekjB-3j9dA:
undetectable		 1ekjA-3j9dA:
14.12
1ekjB-3j9dA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 CYH A 162
ASP A 157
CYH A 851
GLY A 852
 ZN  A1001 (-2.3A)
None
ZN  A1001 (-2.7A)
None
 0.81A 1ekjA-3j9dA:
undetectable
1ekjB-3j9dA:
undetectable		 1ekjA-3j9dA:
14.12
1ekjB-3j9dA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 CYH A 162
ASP A 157
CYH A 851
GLY A 852
 ZN  A1001 (-2.3A)
None
ZN  A1001 (-2.7A)
None
 0.83A 1ekjG-3j9dA:
undetectable
1ekjH-3j9dA:
undetectable		 1ekjG-3j9dA:
14.12
1ekjH-3j9dA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 GLU A 920
LEU A 901
ARG A 891
LEU A 942
 None
 0.91A 1ereE-3j9dA:
undetectable		 1ereE-3j9dA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 GLU A 920
LEU A 901
ARG A 891
LEU A 942
 None
 0.91A 1ereF-3j9dA:
undetectable		 1ereF-3j9dA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.36A 1fkfA-3j9dA:
undetectable		 1fkfA-3j9dA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.37A 1fkjA-3j9dA:
undetectable		 1fkjA-3j9dA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 ARG A 689
ARG A 700
ARG A 685
 None
 1.05A 1l7fA-3j9dA:
undetectable		 1l7fA-3j9dA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 ARG A 689
ARG A 700
ARG A 685
 None
 1.05A 1l7hA-3j9dA:
undetectable		 1l7hA-3j9dA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 PHE A 179
PRO A 618
ALA A 575
SER A 588
 None
 1.09A 1lqtA-3j9dA:
undetectable		 1lqtA-3j9dA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 PHE A 179
PRO A 618
ALA A 575
SER A 588
 None
 1.08A 1lquA-3j9dA:
undetectable		 1lquA-3j9dA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 6 ASN A 751
ARG A 695
ILE A 176
GLY A 749
 None
 1.10A 1oniA-3j9dA:
undetectable
1oniB-3j9dA:
undetectable		 1oniA-3j9dA:
9.15
1oniB-3j9dA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 6 ASN A 751
ARG A 695
ILE A 176
GLY A 749
 None
 1.12A 1oniD-3j9dA:
undetectable
1oniF-3j9dA:
undetectable		 1oniD-3j9dA:
9.15
1oniF-3j9dA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 9 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.44A 1q6iA-3j9dA:
undetectable		 1q6iA-3j9dA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_1
(DIHYDROFOLATE
REDUCTASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 422
GLN A 541
ASN A 412
LEU A 413
ARG A 549
 None
 1.45A 1u70A-3j9dA:
undetectable		 1u70A-3j9dA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.91A 1v54P-3j9dA:
undetectable
1v54W-3j9dA:
undetectable		 1v54P-3j9dA:
13.31
1v54W-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.97A 2eimP-3j9dA:
undetectable
2eimW-3j9dA:
undetectable		 2eimP-3j9dA:
13.31
2eimW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.39A 2fkeA-3j9dA:
undetectable		 2fkeA-3j9dA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 ALA A 586
GLY A 578
ILE A  56
PRO A 545
 None
 0.93A 2fxdB-3j9dA:
undetectable		 2fxdB-3j9dA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 5 ILE A 871
PHE A 944
PHE A 949
ILE A 874
 None
 0.78A 2hjhA-3j9dA:
undetectable		 2hjhA-3j9dA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.32A 2qmjA-3j9dA:
undetectable		 2qmjA-3j9dA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 6 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 1.00A 3abkP-3j9dA:
undetectable
3abkW-3j9dA:
undetectable		 3abkP-3j9dA:
13.31
3abkW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 PRO A 613
LEU A 604
ARG A 607
 None
 0.90A 3aqiA-3j9dA:
undetectable		 3aqiA-3j9dA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.96A 3asnC-3j9dA:
undetectable
3asnJ-3j9dA:
undetectable		 3asnC-3j9dA:
13.31
3asnJ-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.92A 3asnP-3j9dA:
undetectable
3asnW-3j9dA:
undetectable		 3asnP-3j9dA:
13.31
3asnW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.94A 3asoP-3j9dA:
undetectable
3asoW-3j9dA:
undetectable		 3asoP-3j9dA:
13.31
3asoW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 ASP A 415
ASP A 543
ASP A 571
 None
 0.78A 3douA-3j9dA:
undetectable		 3douA-3j9dA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 6 ILE A 675
TYR A 720
ILE A 701
HIS A 696
 None
 1.18A 3eteA-3j9dA:
undetectable
3eteE-3j9dA:
undetectable		 3eteA-3j9dA:
20.02
3eteE-3j9dA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 5 ILE A 675
TYR A 720
ILE A 701
HIS A 696
 None
 1.15A 3eteB-3j9dA:
undetectable
3eteC-3j9dA:
undetectable		 3eteB-3j9dA:
20.02
3eteC-3j9dA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ALA A 730
ASN A 807
LEU A 806
ALA A 809
ILE A 813
 None
 1.04A 3fl9F-3j9dA:
undetectable		 3fl9F-3j9dA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.30A 3ihzA-3j9dA:
undetectable		 3ihzA-3j9dA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.38A 3ihzA-3j9dA:
undetectable		 3ihzA-3j9dA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 TYR A 720
LEU A 724
ILE A 701
ILE A 674
PHE A 717
 None
 1.05A 3kz7A-3j9dA:
undetectable		 3kz7A-3j9dA:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.43A 3o5rA-3j9dA:
undetectable		 3o5rA-3j9dA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.27A 3phaA-3j9dA:
undetectable		 3phaA-3j9dA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ASP A 111
ILE A  78
ILE A 670
ILE A 176
ASP A 750
 None
 1.28A 3phaB-3j9dA:
undetectable		 3phaB-3j9dA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.31A 3phaB-3j9dA:
undetectable		 3phaB-3j9dA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 842
TYR A 843
GLN A 585
LEU A 850
 None
 1.03A 3qeoB-3j9dA:
undetectable		 3qeoB-3j9dA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 CYH A 446
THR A 565
LEU A 765
PHE A 460
VAL A 773
 None
 1.32A 3u9fP-3j9dA:
undetectable
3u9fS-3j9dA:
undetectable		 3u9fP-3j9dA:
11.78
3u9fS-3j9dA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.34A 3uqaA-3j9dA:
undetectable		 3uqaA-3j9dA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.40A 3uqaA-3j9dA:
undetectable		 3uqaA-3j9dA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.33A 3vawA-3j9dA:
undetectable		 3vawA-3j9dA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.39A 3vawA-3j9dA:
undetectable		 3vawA-3j9dA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 TYR A 754
MET A 817
LEU A 763
 None
 0.74A 3vw1D-3j9dA:
undetectable		 3vw1D-3j9dA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 6 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.99A 3wg7C-3j9dA:
undetectable
3wg7J-3j9dA:
undetectable		 3wg7C-3j9dA:
13.31
3wg7J-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 TRP A 860
LEU A 942
LEU A   4
GLY A   5
 None
 0.77A 4c9nA-3j9dA:
undetectable		 4c9nA-3j9dA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 6 ALA A 523
PRO A 524
LEU A 488
THR A 458
 None
 0.88A 4dtzA-3j9dA:
undetectable		 4dtzA-3j9dA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		6 / 11 ASP A 679
ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.43A 4dz2A-3j9dA:
undetectable
4dz2B-3j9dA:
undetectable		 4dz2A-3j9dA:
7.39
4dz2B-3j9dA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		6 / 11 ASP A 679
ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.38A 4dz2A-3j9dA:
undetectable
4dz2B-3j9dA:
undetectable		 4dz2A-3j9dA:
7.39
4dz2B-3j9dA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		6 / 10 ASP A 679
ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.41A 4dz3A-3j9dA:
undetectable		 4dz3A-3j9dA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.34A 4dz3B-3j9dA:
undetectable		 4dz3B-3j9dA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.39A 4dz3B-3j9dA:
undetectable		 4dz3B-3j9dA:
7.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 PHE A 414
ASP A 543
ARG A  57
 None
 0.78A 4eahF-3j9dA:
undetectable		 4eahF-3j9dA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		3 / 3 PHE A 414
ASP A 543
ARG A  57
 None
 0.79A 4eahG-3j9dA:
undetectable		 4eahG-3j9dA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 604
TYR A 600
THR A 621
GLY A 161
 None
 0.95A 4eq4A-3j9dA:
3.7		 4eq4A-3j9dA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 604
TYR A 600
THR A 621
GLY A 161
 None
 0.94A 4eqlA-3j9dA:
2.6		 4eqlA-3j9dA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 604
TYR A 600
THR A 621
GLY A 161
 None
 0.94A 4eqlB-3j9dA:
2.6		 4eqlB-3j9dA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 8 ILE A 713
PHE A 746
GLY A 706
GLU A 708
 None
 1.00A 4fgjA-3j9dA:
undetectable
4fgjB-3j9dA:
undetectable		 4fgjA-3j9dA:
13.67
4fgjB-3j9dA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 854
THR A 845
ASP A 856
ASP A  39
GLU A  45
 None
 1.39A 4i41A-3j9dA:
undetectable		 4i41A-3j9dA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 604
TYR A 600
THR A 621
GLY A 161
 None
 0.92A 4l39B-3j9dA:
3.1		 4l39B-3j9dA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.49A 4laxA-3j9dA:
undetectable		 4laxA-3j9dA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_2
(NEURAMINIDASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 5 LEU A 604
ASP A 599
ARG A 628
ILE A 559
 None
 1.14A 4mwrA-3j9dA:
undetectable		 4mwrA-3j9dA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 PRO A 117
ASN A  47
ALA A 130
GLY A 121
LEU A 122
 None
 1.41A 4oadA-3j9dA:
undetectable		 4oadA-3j9dA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.94A 5b1bP-3j9dA:
undetectable
5b1bW-3j9dA:
undetectable		 5b1bP-3j9dA:
13.31
5b1bW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ASP A 679
ILE A 701
TYR A 745
ALA A 677
ILE A 674
 None
 1.20A 5gpgA-3j9dA:
undetectable		 5gpgA-3j9dA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ASP A 679
ARG A 685
VAL A 712
ILE A 701
TYR A 745
 None
 1.21A 5hw8E-3j9dA:
undetectable		 5hw8E-3j9dA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 11 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.44A 5hwcA-3j9dA:
undetectable		 5hwcA-3j9dA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.96A 5iy5C-3j9dA:
undetectable
5iy5J-3j9dA:
undetectable		 5iy5C-3j9dA:
13.42
5iy5J-3j9dA:
5.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 HIS A 164
THR A 167
GLN A 840
GLU A 153
LEU A 847
 ZN  A1001 (-3.5A)
None
None
None
None
 1.19A 5m66D-3j9dA:
undetectable		 5m66D-3j9dA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 HIS A 658
LEU A 631
ALA A 656
THR A 625
ARG A 563
 None
 1.27A 5nd3B-3j9dA:
undetectable		 5nd3B-3j9dA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 5 LEU A 764
LEU A 763
MET A 472
GLN A 810
 None
 1.40A 5uc3A-3j9dA:
undetectable		 5uc3A-3j9dA:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 5 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.92A 5x19C-3j9dA:
undetectable
5x19J-3j9dA:
undetectable		 5x19C-3j9dA:
13.31
5x19J-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.96A 5x1fP-3j9dA:
undetectable
5x1fW-3j9dA:
undetectable		 5x1fP-3j9dA:
13.31
5x1fW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.94A 5z84C-3j9dA:
undetectable
5z84J-3j9dA:
undetectable		 5z84C-3j9dA:
13.31
5z84J-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.92A 5z85C-3j9dA:
undetectable
5z85J-3j9dA:
undetectable		 5z85C-3j9dA:
13.31
5z85J-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.93A 5zcoC-3j9dA:
undetectable
5zcoJ-3j9dA:
undetectable		 5zcoC-3j9dA:
13.31
5zcoJ-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.94A 5zcqC-3j9dA:
undetectable
5zcqJ-3j9dA:
undetectable		 5zcqC-3j9dA:
13.31
5zcqJ-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A 530
PHE A 569
LEU A 566
PHE A 526
 None
 0.95A 5zcqP-3j9dA:
undetectable
5zcqW-3j9dA:
undetectable		 5zcqP-3j9dA:
13.31
5zcqW-3j9dA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 7 LEU A  80
ILE A  78
THR A  79
TYR A 861
 None
 0.99A 5zsfA-3j9dA:
undetectable
5zsfB-3j9dA:
undetectable		 5zsfA-3j9dA:
6.46
5zsfB-3j9dA:
6.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.30A 6c9zA-3j9dA:
undetectable		 6c9zA-3j9dA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.29A 6ca1A-3j9dA:
undetectable		 6ca1A-3j9dA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.31A 6ca1B-3j9dA:
undetectable		 6ca1B-3j9dA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.30A 6ca3A-3j9dA:
undetectable		 6ca3A-3j9dA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 ILE A 176
ILE A 670
ASP A 669
ARG A 695
ASP A 111
 None
 1.32A 6ca3B-3j9dA:
undetectable		 6ca3B-3j9dA:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		4 / 5 TYR A  49
GLN A 116
GLY A 852
ILE A 854
 None
 1.31A 6debB-3j9dA:
undetectable		 6debB-3j9dA:
6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 12 LEU A 723
ILE A 681
TYR A 720
MET A 793
LEU A 742
 None
 1.32A 6ie8A-3j9dA:
undetectable		 6ie8A-3j9dA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		6 / 12 ASP A 679
ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.41A 6mkeB-3j9dA:
undetectable
6mkeC-3j9dA:
undetectable		 6mkeB-3j9dA:
6.09
6mkeC-3j9dA:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		6 / 10 ASP A 679
ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.48A 6mkeC-3j9dA:
undetectable		 6mkeC-3j9dA:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ARG A 685
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.31A 6mkeD-3j9dA:
undetectable		 6mkeD-3j9dA:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 3j9d OUTER CAPSID PROTEIN
VP2
(Bluetongue
virus) 		5 / 10 ASP A 679
VAL A 712
ILE A 701
TYR A 745
ILE A 674
 None
 1.40A 6mkeD-3j9dA:
undetectable		 6mkeD-3j9dA:
6.09