SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j9e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2201_0
(PROTEIN (METHIONINE
REPRESSOR))		 3j9e VP5
(Bluetongue
virus) 		5 / 9 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.41A 1mj2A-3j9eD:
undetectable		 1mj2A-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC1200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3j9e VP5
(Bluetongue
virus) 		5 / 9 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.45A 1mj2C-3j9eD:
undetectable		 1mj2C-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_A_SAMA199_0
(METHIONINE REPRESSOR)		 3j9e VP5
(Bluetongue
virus) 		5 / 9 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.43A 1mjoA-3j9eD:
undetectable		 1mjoA-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_B_SAMB200_1
(METHIONINE REPRESSOR)		 3j9e VP5
(Bluetongue
virus) 		5 / 9 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.44A 1mjoB-3j9eD:
undetectable		 1mjoB-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_D_SAMD200_0
(METHIONINE REPRESSOR)		 3j9e VP5
(Bluetongue
virus) 		5 / 9 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.44A 1mjoC-3j9eD:
undetectable		 1mjoC-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3j9e VP5
(Bluetongue
virus) 		5 / 11 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.43A 1mjqA-3j9eD:
0.9
1mjqB-3j9eD:
undetectable		 1mjqA-3j9eD:
13.66
1mjqB-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 3j9e VP5
(Bluetongue
virus) 		5 / 10 GLU D 427
ARG D 423
GLU D 405
HIS D 380
LEU D 407
 None
 1.43A 1mjqG-3j9eD:
undetectable
1mjqH-3j9eD:
undetectable		 1mjqG-3j9eD:
13.66
1mjqH-3j9eD:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 GLN D 363
HIS D 365
ARG D 358
 None
 1.08A 1zlqA-3j9eD:
undetectable		 1zlqA-3j9eD:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3j9e VP5
(Bluetongue
virus) 		4 / 6 LEU D 393
ASN D   9
GLN D 498
ILE D 502
 None
 0.91A 2jn3A-3j9eD:
1.9		 2jn3A-3j9eD:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 ASP D 396
SER D 398
ILE D 399
ASP D 375
 None
 1.04A 2xadA-3j9eD:
undetectable		 2xadA-3j9eD:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 ASP D 396
SER D 398
ILE D 399
ASP D 375
 None
 1.04A 2xadB-3j9eD:
undetectable		 2xadB-3j9eD:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 ASP D 396
SER D 398
ILE D 399
ASP D 375
 None
 1.05A 2xadC-3j9eD:
undetectable		 2xadC-3j9eD:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 ASP D 396
SER D 398
ILE D 399
ASP D 375
 None
 1.08A 2xadD-3j9eD:
undetectable		 2xadD-3j9eD:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 LYS D   3
ASN D 434
PRO D 370
TRP D 371
 None
 1.31A 3bjwD-3j9eD:
undetectable		 3bjwD-3j9eD:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 GLU D 103
ASP D 104
ASP D 226
 None
 0.76A 3jb2A-3j9eD:
undetectable		 3jb2A-3j9eD:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 SER D 305
ASP D 472
ASN D 476
 None
 0.39A 3lsfB-3j9eD:
undetectable
3lsfE-3j9eD:
undetectable		 3lsfB-3j9eD:
19.08
3lsfE-3j9eD:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 ASP D 472
ASN D 476
SER D 305
 None
 0.37A 3lsfB-3j9eD:
undetectable
3lsfE-3j9eD:
undetectable		 3lsfB-3j9eD:
19.08
3lsfE-3j9eD:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA802_0
(GLUTAMATE RECEPTOR 2)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 ASP D 472
ASN D 476
SER D 305
 None
 0.90A 3lslA-3j9eD:
undetectable
3lslD-3j9eD:
undetectable		 3lslA-3j9eD:
18.75
3lslD-3j9eD:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 SER D 305
ASP D 472
ASN D 476
 None
 0.89A 3lslA-3j9eD:
undetectable
3lslD-3j9eD:
undetectable		 3lslA-3j9eD:
18.75
3lslD-3j9eD:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3j9e VP5
(Bluetongue
virus) 		5 / 12 THR D 163
ASN D 159
ALA D 251
GLY D 249
ASN D 108
 None
 1.18A 3v3oA-3j9eD:
undetectable		 3v3oA-3j9eD:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 3j9e VP5
(Bluetongue
virus) 		5 / 12 TYR D 194
VAL D 235
ARG D 183
ALA D 175
THR D 174
 None
 1.27A 4fiaA-3j9eD:
undetectable		 4fiaA-3j9eD:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3j9e VP5
(Bluetongue
virus) 		5 / 12 TYR D 194
VAL D 235
ARG D 183
ALA D 175
THR D 174
 None
 1.27A 4fiaA-3j9eD:
undetectable		 4fiaA-3j9eD:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 LEU D 258
TYR D 158
VAL D 130
LEU D 237
 None
 0.95A 4l1xA-3j9eD:
undetectable		 4l1xA-3j9eD:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 GLY D 254
GLY D 249
GLU D 164
LEU D 237
 None
 0.77A 4mwzB-3j9eD:
undetectable		 4mwzB-3j9eD:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3j9e VP5
(Bluetongue
virus) 		4 / 8 ALA D 359
GLN D 361
HIS D 385
HIS D 412
 None
 1.09A 5km8A-3j9eD:
undetectable
5km8B-3j9eD:
undetectable		 5km8A-3j9eD:
15.78
5km8B-3j9eD:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 3j9e VP5
(Bluetongue
virus) 		4 / 5 PHE D 123
SER D 157
ASN D 108
ASP D 104
 None
 1.21A 5kpcA-3j9eD:
undetectable		 5kpcA-3j9eD:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3j9e VP5
(Bluetongue
virus) 		3 / 3 VAL D 345
LYS D 349
MET D 352
 None
 0.82A 5nknA-3j9eD:
undetectable		 5nknA-3j9eD:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3j9e VP5
(Bluetongue
virus) 		5 / 12 ASN D 476
GLY D 504
ALA D 501
LEU D 397
LEU D 491
 None
 1.09A 5xxiA-3j9eD:
undetectable		 5xxiA-3j9eD:
22.53