SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		5 / 7 LEU 7  92
ARG 7  91
LEU 7  47
LEU 7 113
GLY 7 112
 None
 1.31A 1n13D-3j9f7:
undetectable
1n13E-3j9f7:
undetectable		 1n13D-3j9f7:
22.31
1n13E-3j9f7:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 404 ( 1.4A)
NAG  7 404 ( 4.4A)
NAG  7 404 (-3.6A)
 0.85A 1ykiA-3j9f7:
undetectable
1ykiB-3j9f7:
undetectable		 1ykiA-3j9f7:
17.65
1ykiB-3j9f7:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 404 ( 1.4A)
NAG  7 404 ( 4.4A)
NAG  7 404 (-3.6A)
 0.84A 1ykiA-3j9f7:
undetectable
1ykiB-3j9f7:
undetectable		 1ykiA-3j9f7:
17.65
1ykiB-3j9f7:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 404 ( 1.4A)
NAG  7 404 ( 4.4A)
NAG  7 404 (-3.6A)
 0.81A 1ykiC-3j9f7:
undetectable
1ykiD-3j9f7:
undetectable		 1ykiC-3j9f7:
17.65
1ykiD-3j9f7:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 TYR 7 121
ASN 7 120
GLU 7 118
GLY 7 119
 None
NAG  7 404 ( 1.4A)
NAG  7 404 ( 4.4A)
NAG  7 404 (-3.6A)
 0.83A 1ykiC-3j9f7:
undetectable
1ykiD-3j9f7:
undetectable		 1ykiC-3j9f7:
17.65
1ykiD-3j9f7:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 8 ALA 8 175
VAL 8 200
THR 8 201
THR 8 203
 None
 1.28A 2kotB-3j9f8:
undetectable		 2kotB-3j9f8:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 LEU 7 103
VAL 7  31
ARG 7 104
 None
 0.75A 3b0wB-3j9f7:
undetectable		 3b0wB-3j9f7:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		4 / 7 GLU 7 118
VAL 7 141
ARG 7  91
VAL 7  45
 NAG  7 404 ( 4.4A)
None
None
None
 1.26A 5adeA-3j9f7:
undetectable
5adeB-3j9f7:
undetectable		 5adeA-3j9f7:
13.69
5adeB-3j9f7:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 SER 7 107
LEU 7 113
MET 7 110
 NAG  7 401 ( 3.7A)
None
None
 0.84A 5ikrB-3j9f7:
undetectable		 5ikrB-3j9f7:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 PRO 8 173
ARG 8 172
GLU 8 226
 None
 0.89A 5j6hA-3j9f8:
9.3		 5j6hA-3j9f8:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 GLY 8 216
THR 8 239
ASN 8 237
 NAG  8 305 (-4.0A)
None
NAG  8 305 (-1.7A)
 0.67A 5odiG-3j9f8:
undetectable		 5odiG-3j9f8:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 GLY 7 119
VAL 7  45
MET 7 110
 NAG  7 404 (-3.6A)
None
None
 0.60A 5ycpA-3j9f7:
undetectable		 5ycpA-3j9f7:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		5 / 12 ILE 9 299
LEU 9 257
LEU 9 297
LEU 9 286
THR 9 281
 None
 1.21A 6b52A-3j9f9:
undetectable		 6b52A-3j9f9:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3j9f POLIOVIRUS RECEPTOR
(Homo
sapiens) 		3 / 3 ALA 8 175
PHE 8 228
GLN 8 232
 None
 0.72A 6eceA-3j9f8:
undetectable		 6eceA-3j9f8:
17.53