SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 8 GLY A 105
GLY A 104
GLN A 139
TYR A  64
 None
 0.92A 1ekjA-3j9jA:
undetectable
1ekjB-3j9jA:
undetectable		 1ekjA-3j9jA:
16.55
1ekjB-3j9jA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 7 GLY A 105
GLY A 104
GLN A 139
TYR A  64
 None
 0.93A 1ekjE-3j9jA:
undetectable
1ekjF-3j9jA:
undetectable		 1ekjE-3j9jA:
16.55
1ekjF-3j9jA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 6 ALA A  72
TYR A  64
ILE A  67
LEU A 165
 None
 1.04A 1xvaA-3j9jA:
undetectable
1xvaB-3j9jA:
undetectable		 1xvaA-3j9jA:
21.10
1xvaB-3j9jA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 7 ARG A 120
PHE A 116
ILE A 113
PHE A 137
 None
 0.89A 2q6hA-3j9jA:
undetectable		 2q6hA-3j9jA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 7 ARG A 120
PHE A 116
ILE A 113
PHE A 137
 None
 0.88A 2qb4A-3j9jA:
1.0		 2qb4A-3j9jA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 6 ARG A 120
PHE A 116
ILE A 113
PHE A 137
 None
 0.81A 2qeiA-3j9jA:
undetectable		 2qeiA-3j9jA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R3A_A_SAMA304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV39H2)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		5 / 12 GLY A 242
THR A 267
TYR A 204
CYH A 231
LEU A 208
 None
 1.28A 2r3aA-3j9jA:
undetectable		 2r3aA-3j9jA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3j9j TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 1
(Rattus
norvegicus) 		4 / 4 VAL A  35
LEU A  42
ASN A  28
ASP A  31
 None
 1.22A 5vcyA-3j9jA:
undetectable		 5vcyA-3j9jA:
20.77