SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 3j9p MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY A
MEMBER 1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 LEU D 955
ASN D 954
GLY D 958
VAL D 961
LEU D 870
 None
 1.36A 1nhzA-3j9pD:
undetectable		 1nhzA-3j9pD:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3j9p MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY A
MEMBER 1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 10 ALA D 555
LEU D 534
LEU D 567
LEU D 518
ARG D 543
 None
 0.97A 2riwA-3j9pD:
undetectable
2riwB-3j9pD:
undetectable		 2riwA-3j9pD:
12.28
2riwB-3j9pD:
2.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3j9p MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY A
MEMBER 1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		5 / 12 PHE D 746
ILE D 770
GLN D 831
VAL D 839
LEU D 736
 None
 1.32A 4qzuA-3j9pD:
undetectable		 4qzuA-3j9pD:
6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 3j9p MALTOSE-BINDING
PERIPLASMIC PROTEIN,
TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY A
MEMBER 1 CHIMERA
(Escherichia
coli;
Homo
sapiens) 		4 / 8 ILE D 574
ARG D 604
VAL D 564
ASP D 542
 None
 1.13A 5vlmF-3j9pD:
undetectable		 5vlmF-3j9pD:
8.57