SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3j9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  32
ASP A  31
ALA A 142
GLY A 132
SER A 134
 None
 1.13A 1nbiA-3j9qA:
2.8		 1nbiA-3j9qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  32
ASP A  31
ALA A 142
GLY A 132
SER A 134
 None
 1.14A 1nbiB-3j9qA:
2.9		 1nbiB-3j9qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3j9q TUBE
(Pseudomonas
aeruginosa) 		5 / 9 ALA S 101
TYR S 132
GLY S  83
PHE S  81
GLY S 105
 None
 1.23A 1ru9H-3j9qS:
undetectable
1ru9L-3j9qS:
undetectable		 1ru9H-3j9qS:
20.43
1ru9L-3j9qS:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3j9q TUBE
(Pseudomonas
aeruginosa) 		5 / 10 ALA S 101
TYR S 132
GLY S  83
PHE S  81
GLY S 105
 None
 1.29A 1ruaH-3j9qS:
undetectable
1ruaL-3j9qS:
undetectable		 1ruaH-3j9qS:
20.43
1ruaL-3j9qS:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		4 / 7 THR A 211
LEU A 207
VAL A 281
ILE A 153
 None
 0.92A 1t87B-3j9qA:
undetectable		 1t87B-3j9qA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 249
ASN A 248
LEU A 250
ALA A 247
ARG A 234
 None
 1.35A 2aa6A-3j9qA:
undetectable		 2aa6A-3j9qA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 9 GLY A 268
ILE A 226
VAL A 181
ILE A 155
VAL A 129
 None
 1.16A 2nnhB-3j9qA:
undetectable		 2nnhB-3j9qA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 212
PHE A 208
THR A 286
TRP A 218
 None
 1.34A 2q6kA-3j9qA:
4.6		 2q6kA-3j9qA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 212
PHE A 208
THR A 286
TRP A 218
 None
 1.29A 2q6oB-3j9qA:
3.4		 2q6oB-3j9qA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 145
ALA A 140
ALA A 130
LEU A 111
VAL A  98
 None
 0.96A 2yqzB-3j9qA:
undetectable		 2yqzB-3j9qA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3j9q SHEATH
TUBE
(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		5 / 12 GLY S  83
GLY A 317
PHE S  60
ASP S  15
ILE S  14
 None
 1.02A 3eluA-3j9qS:
undetectable		 3eluA-3j9qS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3j9q TUBE
(Pseudomonas
aeruginosa) 		4 / 7 GLU S 135
VAL S 100
THR S 102
VAL S  84
 None
 0.61A 3em0B-3j9qS:
undetectable		 3em0B-3j9qS:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 214
ILE A  19
ALA A  23
 None
 0.53A 4wnwB-3j9qA:
undetectable		 4wnwB-3j9qA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 128
VAL A 129
GLY A 132
SER A 201
LEU A 156
 None
 1.24A 4zbqA-3j9qA:
undetectable		 4zbqA-3j9qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_D_EVPD102_1
(DNA TOPOISOMERASE
2-ALPHA)		 3j9q SHEATH
TUBE
(Pseudomonas
aeruginosa) 		4 / 4 GLY S  16
ASP A 313
ARG S  86
MET S  56
 None
 1.21A 5gwkB-3j9qS:
undetectable		 5gwkB-3j9qS:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.03A 5n0oA-3j9qA:
undetectable		 5n0oA-3j9qA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.03A 5n0rA-3j9qA:
undetectable		 5n0rA-3j9qA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.04A 5n0sA-3j9qA:
undetectable		 5n0sA-3j9qA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.06A 5n0tA-3j9qA:
undetectable		 5n0tA-3j9qA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.03A 5n0wA-3j9qA:
undetectable		 5n0wA-3j9qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.04A 5n0wB-3j9qA:
undetectable		 5n0wB-3j9qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  99
GLY A 100
VAL A  85
VAL A  83
ALA A 138
 None
 1.04A 5n4iA-3j9qA:
undetectable		 5n4iA-3j9qA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 3j9q SHEATH
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 100
GLN A 112
THR A 109
SER A  96
 None
 1.17A 6eqpA-3j9qA:
2.9		 6eqpA-3j9qA:
11.40