SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ja7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3ja7 PORTAL PROTEIN GP20
(Escherichia
virus
T4) 		5 / 11 LEU A 254
TYR A  79
VAL A  92
ILE A  95
LEU A 242
 None
 1.23A 1mrqA-3ja7A:
undetectable		 1mrqA-3ja7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3ja7 PORTAL PROTEIN GP20
(Escherichia
virus
T4) 		5 / 11 LEU A 254
TYR A  79
VAL A  92
ILE A  95
TRP A 150
 None
 1.17A 1mrqA-3ja7A:
undetectable		 1mrqA-3ja7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3ja7 PORTAL PROTEIN GP20
(Escherichia
virus
T4) 		3 / 3 HIS A 136
GLY A 170
ILE A 171
 None
 0.58A 4k50A-3ja7A:
undetectable		 4k50A-3ja7A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3ja7 PORTAL PROTEIN GP20
(Escherichia
virus
T4) 		3 / 3 HIS A 136
GLY A 170
ILE A 171
 None
 0.59A 4k50I-3ja7A:
undetectable		 4k50I-3ja7A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 3ja7 PORTAL PROTEIN GP20
(Escherichia
virus
T4) 		5 / 12 ILE A 171
LEU A 137
VAL A 235
VAL A 236
LEU A 428
 None
 1.13A 5bykA-3ja7A:
undetectable		 5bykA-3ja7A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3ja7 PORTAL PROTEIN GP20
(Escherichia
virus
T4) 		4 / 8 LEU A 174
VAL A 417
LEU A 177
ILE A 156
 None
 1.00A 5v0vA-3ja7A:
undetectable		 5v0vA-3ja7A:
21.41