SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		4 / 8 ILE B 546
ASN B 511
ASN B 509
GLY B 545
 None
 0.95A 1dzmA-3jabB:
undetectable		 1dzmA-3jabB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		5 / 11 VAL B 399
LEU B 396
ILE B 417
ALA B 421
LEU B 424
 None
 1.06A 1eqgB-3jabB:
undetectable		 1eqgB-3jabB:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3jab IGG1-KAPPA 2E8 HEAVY
CHAIN
(Mus
musculus) 		5 / 12 GLY H 104
VAL H   2
GLU H   1
PRO H 101
ALA H  94
 None
 1.39A 1vq1A-3jabH:
undetectable		 1vq1A-3jabH:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		5 / 9 PHE B 505
LEU B 403
LEU B 414
ALA B 421
ALA B 518
 None
 1.17A 2vcvD-3jabB:
3.2		 2vcvD-3jabB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		5 / 9 PHE B 505
LEU B 403
LEU B 414
ALA B 421
ALA B 518
 None
 1.16A 2vcvE-3jabB:
3.3		 2vcvE-3jabB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		5 / 9 PHE B 505
LEU B 403
LEU B 414
ALA B 421
ALA B 518
 None
 1.14A 2vcvH-3jabB:
3.3		 2vcvH-3jabB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		5 / 12 VAL B 399
LEU B 403
LEU B 396
ALA B 421
LEU B 424
 None
 1.05A 3nt1A-3jabB:
undetectable		 3nt1A-3jabB:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		5 / 12 VAL B 399
LEU B 403
LEU B 396
ALA B 421
LEU B 424
 None
 1.06A 3nt1B-3jabB:
undetectable		 3nt1B-3jabB:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3jab GAFB DOMAIN OF
PHOSPHODIESTERASE 2A
(Bos
taurus) 		4 / 7 ILE B 507
GLY B 545
SER B 541
LEU B 403
 None
 0.88A 3v7pA-3jabB:
undetectable		 3v7pA-3jabB:
19.63