SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jar'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CLA_A_CLMA221_0 (TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE)	3jar	MICROTUBULE-ASSOCIAT ED PROTEIN RP/EB FAMILY MEMBER 3 (Homo sapiens)	5 / 11	LEU N 78 PHE N 75 ASN N 104 VAL N 24 ILE N 35	None	1.35A	4claA-3jarN: undetectable	4claA-3jarN: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0Q_A_PX9A201_1 (BETA-LACTOGLOBULIN)	3jar	MICROTUBULE-ASSOCIAT ED PROTEIN RP/EB FAMILY MEMBER 3 (Homo sapiens)	3 / 3	LYS N 112 ILE N 108 ILE N 35	None	0.64A	4y0qA-3jarN: undetectable	4y0qA-3jarN: 21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_C_P06C801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	3jar	MICROTUBULE-ASSOCIAT ED PROTEIN RP/EB FAMILY MEMBER 3 (Homo sapiens)	4 / 7	ILE N 35 VAL N 61 ASN N 25 PHE N 63	None	0.83A	5hieC-3jarN: undetectable	5hieC-3jarN: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZV2_B_LEVB801_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1)	3jar	MICROTUBULE-ASSOCIAT ED PROTEIN RP/EB FAMILY MEMBER 3 (Homo sapiens)	3 / 3	TYR N 124 LEU N 51 ASP N 116	None	0.85A	5zv2B-3jarN: undetectable	5zv2B-3jarN: 20.25

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4CLA_A_CLMA221_0","TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE","3jar","MICROTUBULE-ASSOCIATED PROTEIN RP\/EB FAMILY MEMBER 3","Homo sapiens",5,"LEU N  78;PHE N  75;ASN N 104;VAL N  24;ILE N  35","None","1.35A","4claA-3jarN:undetectable","4claA-3jarN:20.26"],["4Y0Q_A_PX9A201_1","BETA-LACTOGLOBULIN","3jar","MICROTUBULE-ASSOCIATED PROTEIN RP\/EB FAMILY MEMBER 3","Homo sapiens",3,"LYS N 112;ILE N 108;ILE N  35","None","0.64A","4y0qA-3jarN:undetectable","4y0qA-3jarN:21.29"],["5HIE_C_P06C801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","3jar","MICROTUBULE-ASSOCIATED PROTEIN RP\/EB FAMILY MEMBER 3","Homo sapiens",4,"ILE N  35;VAL N  61;ASN N  25;PHE N  63","None","0.83A","5hieC-3jarN:undetectable","5hieC-3jarN:19.87"],["5ZV2_B_LEVB801_2","FIBROBLAST GROWTH FACTOR RECEPTOR 1","3jar","MICROTUBULE-ASSOCIATED PROTEIN RP\/EB FAMILY MEMBER 3","Homo sapiens",3,"TYR N 124;LEU N  51;ASP N 116","None","0.85A","5zv2B-3jarN:undetectable","5zv2B-3jarN:20.25"]]