SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jaz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 LEU D 160
ALA D 161
VAL D 193
ILE D  19
LEU D 186
 None
 1.02A 1fm6U-3jazD:
undetectable		 1fm6U-3jazD:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_A_CHCA1001_1
(BILE ACID RECEPTOR)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 ILE D 230
PHE D  77
ILE D 198
TYR D 134
TRP D 290
 None
 0.96A 1ot7A-3jazD:
0.0		 1ot7A-3jazD:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 9 LEU D  32
LEU D  34
LEU D  35
PHE D 229
LEU D 189
 None
 1.24A 2f78A-3jazD:
undetectable		 2f78A-3jazD:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 9 LEU D  32
LEU D  34
LEU D  35
PHE D 229
LEU D 189
 None
 1.26A 2f78B-3jazD:
undetectable		 2f78B-3jazD:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 9 LEU D  32
LEU D  34
LEU D  35
PHE D 229
LEU D 189
 None
 1.19A 2f7aA-3jazD:
undetectable		 2f7aA-3jazD:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		3 / 3 SER D 141
GLY D 138
GLY D  88
 None
 0.45A 3bogA-3jazD:
undetectable
3bogC-3jazD:
undetectable		 3bogA-3jazD:
undetectable
3bogC-3jazD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 TYR D 134
ILE D 198
PHE D 287
LEU D 283
LEU D 137
 None
 1.12A 3em0B-3jazD:
undetectable		 3em0B-3jazD:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 ILE D 230
THR D 233
ILE D  79
ILE D 187
SER D 188
 None
 1.19A 3kpdB-3jazD:
undetectable		 3kpdB-3jazD:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 ILE D  72
ALA D  75
ALA D 140
LEU D 137
LEU D 285
 None
 1.07A 3uvvA-3jazD:
undetectable		 3uvvA-3jazD:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		3 / 3 LYS D  47
ASN D 291
ASP D 151
 None
 0.49A 4o1eA-3jazD:
undetectable		 4o1eA-3jazD:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4J_A_LNRA412_1
(ENDOTHIAPEPSIN)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 9 SER D 185
SER D 181
PHE D 179
ASP D 249
LEU D 252
 None
 1.26A 4y4jA-3jazD:
undetectable		 4y4jA-3jazD:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 7 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.92A 4ze3A-3jazD:
undetectable		 4ze3A-3jazD:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 GLY D 106
GLY D 109
ILE D 111
ILE D 203
PHE D  15
 None
 1.19A 4zvmA-3jazD:
undetectable
4zvmB-3jazD:
undetectable		 4zvmA-3jazD:
18.96
4zvmB-3jazD:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		4 / 8 PHE D  31
ILE D  19
PHE D 179
THR D 233
 None
 0.89A 5esjA-3jazD:
0.6		 5esjA-3jazD:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		3 / 3 THR D 233
THR D 268
ARG D 265
 None
 1.04A 5wm2A-3jazD:
undetectable		 5wm2A-3jazD:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		5 / 12 LEU D 199
ILE D 203
PHE D 282
CYH D 206
LEU D  93
 None
 1.23A 6a7pA-3jazD:
undetectable		 6a7pA-3jazD:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 3jaz VIRAL STRUCTURAL
PROTEIN 5
(Cypovirus
1) 		3 / 3 LYS D  47
VAL D  45
ASP D 151
 None
 0.65A 6fgdA-3jazD:
undetectable		 6fgdA-3jazD:
23.81