SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 3jb4 VP1
VP3
(Parechovirus
B;
Parechovirus
B) 		3 / 3 ALA C  44
VAL A 181
TRP A 150
 None
 0.98A 1gmkA-3jb4C:
undetectable
1gmkB-3jb4C:
undetectable		 1gmkA-3jb4C:
13.58
1gmkB-3jb4C:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 3jb4 VP1
VP3
(Parechovirus
B;
Parechovirus
B) 		3 / 3 ALA C  44
VAL A 181
TRP A 150
 None
 0.94A 1gmkC-3jb4C:
undetectable
1gmkD-3jb4C:
undetectable		 1gmkC-3jb4C:
13.58
1gmkD-3jb4C:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3jb4 VP0
VP3
(Parechovirus
B;
Parechovirus
B) 		4 / 8 GLU C  79
SER B 173
ILE C 225
ASP C 105
 None
 0.84A 1jg4A-3jb4C:
undetectable		 1jg4A-3jb4C:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3jb4 VP0
(Parechovirus
B) 		3 / 3 TRP B 216
HIS B 163
MET B 166
 None
 1.31A 1l5qB-3jb4B:
undetectable		 1l5qB-3jb4B:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3jb4 VP1
(Parechovirus
B) 		4 / 7 THR A  99
PHE A  97
SER A 138
LEU A 163
 None
 0.98A 1qcaA-3jb4A:
undetectable		 1qcaA-3jb4A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3jb4 VP1
VP0
VP3
(Parechovirus
B;
Parechovirus
B;
Parechovirus
B) 		5 / 12 ILE C 225
GLN C 224
ALA A 235
GLY C  78
GLY B 172
 None
 1.06A 1rjdA-3jb4C:
undetectable		 1rjdA-3jb4C:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3jb4 VP1
VP0
VP3
(Parechovirus
B;
Parechovirus
B;
Parechovirus
B) 		5 / 12 ILE C 225
GLN C 224
ALA A 235
GLY C  78
GLY B 172
 None
 1.03A 1rjdC-3jb4C:
undetectable		 1rjdC-3jb4C:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.96A 1rxcB-3jb4B:
undetectable		 1rxcB-3jb4B:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.93A 1rxcE-3jb4B:
undetectable		 1rxcE-3jb4B:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.91A 1rxcI-3jb4B:
undetectable		 1rxcI-3jb4B:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.96A 1rxcK-3jb4B:
undetectable		 1rxcK-3jb4B:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3jb4 VP3
(Parechovirus
B) 		4 / 7 LYS C 132
PHE C 129
LEU C 201
PHE C 103
 None
 1.01A 1v55P-3jb4C:
undetectable
1v55W-3jb4C:
undetectable		 1v55P-3jb4C:
19.72
1v55W-3jb4C:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3jb4 VP1
VP3
(Parechovirus
B;
Parechovirus
B) 		4 / 4 GLY A  89
SER A 223
ILE C  31
HIS A 133
 None
 1.11A 1yajJ-3jb4A:
undetectable		 1yajJ-3jb4A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jb4 VP3
(Parechovirus
B) 		4 / 7 LYS C 132
PHE C 129
LEU C 201
PHE C 103
 None
 1.05A 2eimP-3jb4C:
undetectable
2eimW-3jb4C:
undetectable		 2eimP-3jb4C:
19.72
2eimW-3jb4C:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jb4 VP3
(Parechovirus
B) 		4 / 7 LYS C 132
PHE C 129
LEU C 201
PHE C 103
 None
 1.01A 2einC-3jb4C:
undetectable
2einJ-3jb4C:
undetectable		 2einC-3jb4C:
19.72
2einJ-3jb4C:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3jb4 VP3
(Parechovirus
B) 		5 / 11 LEU C 201
VAL C  75
GLN C 224
ILE C 203
PHE C  90
 None
 1.18A 2q6hA-3jb4C:
undetectable		 2q6hA-3jb4C:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3jb4 VP3
(Parechovirus
B) 		5 / 11 LEU C 201
VAL C  75
GLN C 224
ILE C 203
PHE C  90
 None
 1.20A 2qeiA-3jb4C:
undetectable		 2qeiA-3jb4C:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3jb4 VP0
(Parechovirus
B) 		5 / 12 TYR B 196
ALA B 203
VAL B 133
THR B 110
ASP B 208
 None
 1.30A 2qo4A-3jb4B:
undetectable		 2qo4A-3jb4B:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3jb4 VP0
(Parechovirus
B) 		5 / 12 TYR B 196
ALA B 203
VAL B 133
THR B 110
ASP B 208
 None
 1.30A 2qo6A-3jb4B:
undetectable		 2qo6A-3jb4B:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3jb4 VP3
(Parechovirus
B) 		4 / 5 PHE C 129
PHE C 149
LEU C 201
PHE C 103
 None
 1.35A 2y69P-3jb4C:
undetectable
2y69W-3jb4C:
undetectable		 2y69P-3jb4C:
19.72
2y69W-3jb4C:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3jb4 VP1
(Parechovirus
B) 		4 / 8 ILE A 132
HIS A 110
VAL A  94
GLY A  95
 None
 0.84A 3em0B-3jb4A:
undetectable		 3em0B-3jb4A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 3jb4 VP0
VP1
VP3
(Parechovirus
B) 		5 / 9 ASN B 183
ALA B 185
GLY C 173
ILE C 172
THR A  49
 None
 1.21A 3spkA-3jb4B:
undetectable		 3spkA-3jb4B:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.94A 4e1vA-3jb4B:
undetectable		 4e1vA-3jb4B:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.98A 4e1vC-3jb4B:
undetectable		 4e1vC-3jb4B:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.93A 4e1vD-3jb4B:
undetectable		 4e1vD-3jb4B:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.97A 4e1vE-3jb4B:
undetectable		 4e1vE-3jb4B:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.86A 4e1vG-3jb4B:
undetectable		 4e1vG-3jb4B:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3jb4 VP0
VP3
(Parechovirus
B) 		4 / 8 THR B 175
GLY B 172
ARG B 102
VAL C  75
 None
 0.92A 4e1vH-3jb4B:
undetectable		 4e1vH-3jb4B:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3jb4 VP0
(Parechovirus
B) 		3 / 3 ILE B 256
ASP B 209
ARG B 248
 None
 0.62A 4pstA-3jb4B:
undetectable		 4pstA-3jb4B:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3jb4 VP0
(Parechovirus
B) 		5 / 11 PHE B 115
ALA B 123
PRO B 122
VAL B  89
ILE B 235
 None
 1.26A 4uuuB-3jb4B:
undetectable		 4uuuB-3jb4B:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3jb4 VP1
VP3
(Parechovirus
B) 		5 / 12 PHE A 123
VAL A  84
ILE A  87
TYR C 122
PHE C 233
 None
 1.19A 5b8iC-3jb4A:
undetectable		 5b8iC-3jb4A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 3jb4 VP1
VP3
(Parechovirus
B) 		5 / 11 PHE A 123
VAL A  84
ILE A  87
TYR C 122
PHE C 233
 None
 1.17A 5huaA-3jb4A:
undetectable		 5huaA-3jb4A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3jb4 VP1
(Parechovirus
B) 		3 / 3 SER A 165
LEU A 179
MET A 169
 None
 0.85A 5ikrB-3jb4A:
undetectable		 5ikrB-3jb4A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3jb4 VP3
(Parechovirus
B) 		4 / 8 LEU C 145
VAL C 102
LEU C 209
ILE C  96
 None
 0.95A 5v0vA-3jb4C:
undetectable		 5v0vA-3jb4C:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3jb4 VP3
(Parechovirus
B) 		4 / 6 LYS C 132
PHE C 129
LEU C 201
PHE C 103
 None
 1.12A 5w97C-3jb4C:
undetectable
5w97J-3jb4C:
undetectable		 5w97C-3jb4C:
19.72
5w97J-3jb4C:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3jb4 VP1
(Parechovirus
B) 		3 / 3 LEU A 130
ASP A  85
ILE A  87
 None
 0.63A 6dh0B-3jb4A:
undetectable		 6dh0B-3jb4A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3jb4 VP0
VP3
(Parechovirus
B;
Parechovirus
B) 		5 / 12 THR B 222
VAL C 219
ASN B 183
VAL B 217
TYR C  89
 None
 1.48A 6iblB-3jb4B:
undetectable		 6iblB-3jb4B:
20.14