SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jbb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3jbb ALLOPHYCOCYANIN BETA
CHAIN
(Halomicronema
hongdechloris) 		5 / 12 LEU B 153
ALA B  92
LEU B  89
VAL B 141
ALA B  40
 None
 1.10A 1sa1A-3jbbB:
undetectable
1sa1B-3jbbB:
undetectable		 1sa1A-3jbbB:
18.14
1sa1B-3jbbB:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3jbb ALLOPHYCOCYANIN BETA
CHAIN
(Halomicronema
hongdechloris) 		5 / 12 LEU B 153
ALA B  92
LEU B  89
VAL B 141
ALA B  40
 None
 1.09A 1sa1C-3jbbB:
undetectable
1sa1D-3jbbB:
undetectable		 1sa1C-3jbbB:
18.14
1sa1D-3jbbB:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3jbb ALLOPHYCOCYANIN BETA
CHAIN
(Halomicronema
hongdechloris) 		5 / 12 THR B 126
ILE B 156
TYR B 116
ILE B 123
LEU B 112
 CYC  B 201 (-4.2A)
None
CYC  B 201 (-4.9A)
SO4  B 203 (-4.2A)
CYC  B 201 ( 4.4A)
 1.04A 1z9hD-3jbbB:
undetectable		 1z9hD-3jbbB:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3jbb ALLOPHYCOCYANIN BETA
CHAIN
(Halomicronema
hongdechloris) 		3 / 3 ASP B  84
ARG B  83
TYR B  87
 CYC  B 201 (-2.7A)
None
CYC  B 201 (-4.2A)
 1.03A 5a7mA-3jbbB:
undetectable		 5a7mA-3jbbB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3jbb ALLOPHYCOCYANIN BETA
CHAIN
(Halomicronema
hongdechloris) 		3 / 3 ASP B  84
ARG B  83
TYR B  87
 CYC  B 201 (-2.7A)
None
CYC  B 201 (-4.2A)
 1.03A 5a7mB-3jbbB:
undetectable		 5a7mB-3jbbB:
11.59