SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jbe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZGW_A_ADNA1301_1 (BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3jbe	NANOBODY VHH PVSS8A (Camelus dromedarius)	4 / 7	ARG 7 45 GLU 7 46 ALA 7 97 ALA 7 35	None	1.08A	2zgwA-3jbe7: undetectable	2zgwA-3jbe7: 19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8W_A_FLPA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	3jbe	NANOBODY VHH PVSS8A (Camelus dromedarius)	5 / 12	VAL 7 64 LEU 7 18 TYR 7 94 LEU 7 81 GLY 7 15	None	1.03A	3n8wA-3jbe7: undetectable	3n8wA-3jbe7: 12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA311_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	3jbe	NANOBODY VHH PVSS8A (Camelus dromedarius)	3 / 3	GLN 7 72 THR 7 53 THR 7 52	None	0.82A	4fu9A-3jbe7: undetectable	4fu9A-3jbe7: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MBS_A_MRVA1101_2 (CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN)	3jbe	NANOBODY VHH PVSS8A (Camelus dromedarius)	4 / 7	GLN 7 121 THR 7 120 LEU 7 20 THR 7 69	None	1.03A	4mbsA-3jbe7: undetectable	4mbsA-3jbe7: 13.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZGW_A_ADNA1301_1","BIOTIN--[ACETYL-COA-CARBOXYLASE] LIGASE","3jbe","NANOBODY VHH PVSS8A","Camelus dromedarius",4,"ARG 7  45;GLU 7  46;ALA 7  97;ALA 7  35","None","1.08A","2zgwA-3jbe7:undetectable","2zgwA-3jbe7:19.15"],["3N8W_A_FLPA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","3jbe","NANOBODY VHH PVSS8A","Camelus dromedarius",5,"VAL 7  64;LEU 7  18;TYR 7  94;LEU 7  81;GLY 7  15","None","1.03A","3n8wA-3jbe7:undetectable","3n8wA-3jbe7:12.12"],["4FU9_A_ACTA311_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","3jbe","NANOBODY VHH PVSS8A","Camelus dromedarius",3,"GLN 7  72;THR 7  53;THR 7  52","None","0.82A","4fu9A-3jbe7:undetectable","4fu9A-3jbe7:20.73"],["4MBS_A_MRVA1101_2","CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN","3jbe","NANOBODY VHH PVSS8A","Camelus dromedarius",4,"GLN 7 121;THR 7 120;LEU 7  20;THR 7  69","None","1.03A","4mbsA-3jbe7:undetectable","4mbsA-3jbe7:13.45"]]