SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jbl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IG3_B_VIBB501_1 (THIAMIN PYROPHOSPHOKINASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	GLN K 372 LEU K 421 SER K 375 ASN K 374	None	1.21A	1ig3A-3jblK: undetectable 1ig3B-3jblK: undetectable	1ig3A-3jblK: 15.82 1ig3B-3jblK: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KB9_A_PCFA514_0 (CYTOCHROME B CYTOCHROME C1, HEME PROTEIN UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX CORE PROTEIN I UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	SER K 722 HIS K 693 ILE K 534 VAL K 707	None SEP K 533 ( 3.9A) SEP K 533 ( 4.0A) None	1.14A	1kb9A-3jblK: undetectable 1kb9C-3jblK: undetectable 1kb9D-3jblK: undetectable 1kb9E-3jblK: undetectable	1kb9A-3jblK: 19.50 1kb9C-3jblK: 17.36 1kb9D-3jblK: 12.96 1kb9E-3jblK: 11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PJ7_A_FFOA2887_1 (N,N-DIMETHYLGLYCINE OXIDASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	3 / 3	ASP K 544 THR K 540 GLU K 824	None	0.52A	1pj7A-3jblK: undetectable	1pj7A-3jblK: 23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UPF_B_URFB999_1 (URACIL PHOSPHORIBOSYLTRANSF ERASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	ALA K 784 TYR K 810 ILE K 811 ILE K 804	None	0.76A	1upfB-3jblK: undetectable	1upfB-3jblK: 13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLX_B_CIOB102_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 12	TYR K 493 THR K 450 PHE K 363 GLN K 447 PHE K 406	None	1.45A	1xlxB-3jblK: undetectable	1xlxB-3jblK: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOM_B_CIOB601_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 12	TYR K 493 THR K 450 PHE K 363 GLN K 447 PHE K 406	None	1.31A	1xomB-3jblK: undetectable	1xomB-3jblK: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_A_SAMA301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	3 / 3	LYS K 469 ASP K 391 ASP K 385	None	0.85A	2br4A-3jblK: undetectable	2br4A-3jblK: 13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DR2_A_TRPA479_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 11	GLY K 350 GLN K 317 ILE K 309 CYH K 345 GLN K 348	None	1.38A	2dr2A-3jblK: undetectable	2dr2A-3jblK: 17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_C_STIC600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 6	LEU K 738 MET K 775 ILE K 756 MET K 718	None	1.07A	2hyyC-3jblK: undetectable	2hyyC-3jblK: 14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NSI_A_H4BA600_1 (PROTEIN (NITRIC OXIDE SYNTHASE))	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	MET K 958 ILE K 924 TRP K 954 PHE K 972	None	1.24A	2nsiA-3jblK: undetectable 2nsiB-3jblK: undetectable	2nsiA-3jblK: 19.62 2nsiB-3jblK: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NSI_B_H4BB601_1 (PROTEIN (NITRIC OXIDE SYNTHASE))	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	TRP K 954 PHE K 972 MET K 958 ILE K 924	None	1.21A	2nsiA-3jblK: undetectable 2nsiB-3jblK: undetectable	2nsiA-3jblK: 19.62 2nsiB-3jblK: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NSI_C_H4BC602_1 (PROTEIN (NITRIC OXIDE SYNTHASE))	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	MET K 958 ILE K 924 TRP K 954 PHE K 972	None	1.24A	2nsiC-3jblK: undetectable 2nsiD-3jblK: undetectable	2nsiC-3jblK: 19.62 2nsiD-3jblK: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NSI_D_H4BD603_1 (PROTEIN (NITRIC OXIDE SYNTHASE))	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	TRP K 954 PHE K 972 MET K 958 ILE K 924	None	1.25A	2nsiC-3jblK: undetectable 2nsiD-3jblK: undetectable	2nsiC-3jblK: 19.62 2nsiD-3jblK: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAV_F_CSCF1383_2 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	3 / 3	LEU K 717 MET K 714 MET K 793	None	0.62A	2vavF-3jblK: undetectable	2vavF-3jblK: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAV_L_CSCL1383_2 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 4	THR K 716 LEU K 717 MET K 714 MET K 793	None	0.74A	2vavL-3jblK: 1.6	2vavL-3jblK: 18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_A_SAMA801_1 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	ARG K 745 ASP K 668 GLU K 720 SER K 722	None	0.95A	2zw9A-3jblK: undetectable	2zw9A-3jblK: 22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E7G_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	MET K 958 ILE K 924 TRP K 954 PHE K 972	None	1.30A	3e7gA-3jblK: undetectable 3e7gB-3jblK: undetectable	3e7gA-3jblK: 19.30 3e7gB-3jblK: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E7G_B_H4BB1902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	TRP K 954 PHE K 972 MET K 958 ILE K 924	None	1.28A	3e7gA-3jblK: undetectable 3e7gB-3jblK: undetectable	3e7gA-3jblK: 19.30 3e7gB-3jblK: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E7G_C_H4BC2902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	MET K 958 ILE K 924 TRP K 954 PHE K 972	None	1.23A	3e7gC-3jblK: undetectable 3e7gD-3jblK: undetectable	3e7gC-3jblK: 19.30 3e7gD-3jblK: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EJ8_A_H4BA1902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	MET K 958 ILE K 924 TRP K 954 PHE K 972	None	1.32A	3ej8A-3jblK: 0.0 3ej8B-3jblK: 0.0	3ej8A-3jblK: 19.62 3ej8B-3jblK: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EJ8_D_H4BD4902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	TRP K 954 PHE K 972 MET K 958 ILE K 924	None	1.26A	3ej8C-3jblK: 0.0 3ej8D-3jblK: 0.0	3ej8C-3jblK: 19.62 3ej8D-3jblK: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW5_A_TOPA208_1 (DIHYDROFOLATE REDUCTASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 11	LEU K 704 LEU K 666 VAL K 664 ILE K 677 PHE K 684	None	1.12A	3jw5A-3jblK: undetectable	3jw5A-3jblK: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP2_B_PNNB5002_0 (TRANSCRIPTIONAL REGULATOR TCAR)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 5	ASN K 670 ALA K 698 ALA K 699 ARG K 703	None	1.22A	3kp2B-3jblK: undetectable	3kp2B-3jblK: 10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UQ6_B_ADNB401_2 (ADENOSINE KINASE, PUTATIVE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 5	LEU K 293 GLY K 291 MET K 274 ASN K 268	None	1.33A	3uq6B-3jblK: undetectable	3uq6B-3jblK: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 12	LEU K 796 LEU K 768 LEU K 741 ILE K 811 THR K 733	None	1.25A	4f4dA-3jblK: undetectable	4f4dA-3jblK: 17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_A_RKEA401_1 (PROTON-GATED ION CHANNEL)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	ASP K 727 ASP K 728 VAL K 719 LEU K 746	None	1.06A	4f8hA-3jblK: undetectable 4f8hB-3jblK: undetectable	4f8hA-3jblK: 16.03 4f8hB-3jblK: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_C_RKEC401_1 (PROTON-GATED ION CHANNEL)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	ASP K 727 ASP K 728 VAL K 719 LEU K 746	None	1.09A	4f8hC-3jblK: undetectable 4f8hD-3jblK: undetectable	4f8hC-3jblK: 16.03 4f8hD-3jblK: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_D_RKED401_1 (PROTON-GATED ION CHANNEL)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	ASP K 727 ASP K 728 VAL K 719 LEU K 746	None	1.07A	4f8hD-3jblK: undetectable 4f8hE-3jblK: undetectable	4f8hD-3jblK: 16.03 4f8hE-3jblK: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F8H_E_RKEE401_1 (PROTON-GATED ION CHANNEL)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	VAL K 719 LEU K 746 ASP K 727 ASP K 728	None	1.10A	4f8hA-3jblK: undetectable 4f8hE-3jblK: undetectable	4f8hA-3jblK: 16.03 4f8hE-3jblK: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L1X_A_STRA402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	LEU K 931 VAL K 960 LEU K 909 LEU K 939	None	0.96A	4l1xA-3jblK: undetectable	4l1xA-3jblK: 16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJG_A_SAMA302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 12	GLU K 542 GLU K 720 VAL K 523 ASP K 544 GLN K 543	None	1.50A	4njgA-3jblK: 1.7	4njgA-3jblK: 12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJG_B_SAMB302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 12	GLU K 542 GLU K 720 VAL K 523 ASP K 544 GLN K 543	None	1.50A	4njgB-3jblK: 1.4	4njgB-3jblK: 12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NOS_B_H4BB1011_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	TRP K 954 PHE K 972 MET K 958 ILE K 924	None	1.26A	4nosA-3jblK: undetectable 4nosB-3jblK: undetectable	4nosA-3jblK: 19.27 4nosB-3jblK: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NOS_C_H4BC2011_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 7	MET K 958 ILE K 924 TRP K 954 PHE K 972	None	1.27A	4nosC-3jblK: undetectable 4nosD-3jblK: undetectable	4nosC-3jblK: 19.27 4nosD-3jblK: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OK1_A_198A1001_2 (ANDROGEN RECEPTOR)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	LEU K 847 ASN K 843 MET K 808 LEU K 787	None	0.97A	4ok1A-3jblK: undetectable	4ok1A-3jblK: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OLB_A_TRPA902_0 (PROTEIN ARGONAUTE-2)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 5	TYR K 487 LYS K 476 LEU K 398 GLU K 399	None	1.41A	4olbA-3jblK: 2.1	4olbA-3jblK: 21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PST_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	3 / 3	ILE K 669 ASP K 615 ARG K 619	None	0.72A	4pstA-3jblK: undetectable	4pstA-3jblK: 9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RTS_A_SAMA301_0 (DNA ADENINE METHYLASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	5 / 12	GLY K1004 PHE K 972 GLY K 946 ILE K 924 ASP K 971	None	1.25A	4rtsA-3jblK: undetectable	4rtsA-3jblK: 16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G48_A_1FLA1375_1 (DNA POLYMERASE III SUBUNIT BETA)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	THR K 278 ILE K 287 PRO K 164 LEU K 166	None	0.81A	5g48A-3jblK: undetectable	5g48A-3jblK: 19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HS1_A_VORA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 8	PHE K 957 GLY K 928 LEU K 912 LEU K 939	None	0.87A	5hs1A-3jblK: undetectable	5hs1A-3jblK: 19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 6	ILE K 677 ILE K 591 LEU K 614 PHE K 596	None	1.03A	5vkqC-3jblK: undetectable 5vkqD-3jblK: undetectable	5vkqC-3jblK: 20.32 5vkqD-3jblK: 20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEA_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 5	LEU K 455 TYR K 487 LEU K 398 GLU K 399	None	1.23A	5weaA-3jblK: 2.1	5weaA-3jblK: 21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_C_ADNC501_2 (-)	3jbl	NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 (Mus musculus)	4 / 5	THR K 281 THR K 337 HIS K 443 GLY K 425	None	1.07A	6gbnC-3jblK: undetectable	6gbnC-3jblK: 19.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IG3_B_VIBB501_1","THIAMIN PYROPHOSPHOKINASE;THIAMIN PYROPHOSPHOKINASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"GLN K 372;LEU K 421;SER K 375;ASN K 374","None","1.21A","1ig3A-3jblK:undetectable;1ig3B-3jblK:undetectable","1ig3A-3jblK:15.82;1ig3B-3jblK:15.82"],["1KB9_A_PCFA514_0","CYTOCHROME B;CYTOCHROME C1, HEME PROTEIN;UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX CORE PROTEIN I;UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"SER K 722;HIS K 693;ILE K 534;VAL K 707","None;SEP K 533 ( 3.9A);SEP K 533 ( 4.0A);None","1.14A","1kb9A-3jblK:undetectable;1kb9C-3jblK:undetectable;1kb9D-3jblK:undetectable;1kb9E-3jblK:undetectable","1kb9A-3jblK:19.50;1kb9C-3jblK:17.36;1kb9D-3jblK:12.96;1kb9E-3jblK:11.82"],["1PJ7_A_FFOA2887_1","N,N-DIMETHYLGLYCINE OXIDASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",3,"ASP K 544;THR K 540;GLU K 824","None","0.52A","1pj7A-3jblK:undetectable","1pj7A-3jblK:23.22"],["1UPF_B_URFB999_1","URACIL PHOSPHORIBOSYLTRANSFERASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ALA K 784;TYR K 810;ILE K 811;ILE K 804","None","0.76A","1upfB-3jblK:undetectable","1upfB-3jblK:13.55"],["1XLX_B_CIOB102_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4B","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"TYR K 493;THR K 450;PHE K 363;GLN K 447;PHE K 406","None","1.45A","1xlxB-3jblK:undetectable","1xlxB-3jblK:19.12"],["1XOM_B_CIOB601_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"TYR K 493;THR K 450;PHE K 363;GLN K 447;PHE K 406","None","1.31A","1xomB-3jblK:undetectable","1xomB-3jblK:18.51"],["2BR4_A_SAMA301_1","CEPHALOSPORIN HYDROXYLASE CMCI","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",3,"LYS K 469;ASP K 391;ASP K 385","None","0.85A","2br4A-3jblK:undetectable","2br4A-3jblK:13.30"],["2DR2_A_TRPA479_0","TRYPTOPHANYL-TRNA SYNTHETASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"GLY K 350;GLN K 317;ILE K 309;CYH K 345;GLN K 348","None","1.38A","2dr2A-3jblK:undetectable","2dr2A-3jblK:17.18"],["2HYY_C_STIC600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"LEU K 738;MET K 775;ILE K 756;MET K 718","None","1.07A","2hyyC-3jblK:undetectable","2hyyC-3jblK:14.03"],["2NSI_A_H4BA600_1","PROTEIN (NITRIC OXIDE SYNTHASE);PROTEIN (NITRIC OXIDE SYNTHASE)","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"MET K 958;ILE K 924;TRP K 954;PHE K 972","None","1.24A","2nsiA-3jblK:undetectable;2nsiB-3jblK:undetectable","2nsiA-3jblK:19.62;2nsiB-3jblK:19.62"],["2NSI_B_H4BB601_1","PROTEIN (NITRIC OXIDE SYNTHASE);PROTEIN (NITRIC OXIDE SYNTHASE)","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"TRP K 954;PHE K 972;MET K 958;ILE K 924","None","1.21A","2nsiA-3jblK:undetectable;2nsiB-3jblK:undetectable","2nsiA-3jblK:19.62;2nsiB-3jblK:19.62"],["2NSI_C_H4BC602_1","PROTEIN (NITRIC OXIDE SYNTHASE);PROTEIN (NITRIC OXIDE SYNTHASE)","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"MET K 958;ILE K 924;TRP K 954;PHE K 972","None","1.24A","2nsiC-3jblK:undetectable;2nsiD-3jblK:undetectable","2nsiC-3jblK:19.62;2nsiD-3jblK:19.62"],["2NSI_D_H4BD603_1","PROTEIN (NITRIC OXIDE SYNTHASE);PROTEIN (NITRIC OXIDE SYNTHASE)","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"TRP K 954;PHE K 972;MET K 958;ILE K 924","None","1.25A","2nsiC-3jblK:undetectable;2nsiD-3jblK:undetectable","2nsiC-3jblK:19.62;2nsiD-3jblK:19.62"],["2VAV_F_CSCF1383_2","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",3,"LEU K 717;MET K 714;MET K 793","None","0.62A","2vavF-3jblK:undetectable","2vavF-3jblK:18.11"],["2VAV_L_CSCL1383_2","ACETYL-COA--DEACETYLCEPHALOSPORIN C ACETYLTRANSFERASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"THR K 716;LEU K 717;MET K 714;MET K 793","None","0.74A","2vavL-3jblK:1.6","2vavL-3jblK:18.11"],["2ZW9_A_SAMA801_1","LEUCINE CARBOXYL METHYLTRANSFERASE 2","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ARG K 745;ASP K 668;GLU K 720;SER K 722","None","0.95A","2zw9A-3jblK:undetectable","2zw9A-3jblK:22.21"],["3E7G_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"MET K 958;ILE K 924;TRP K 954;PHE K 972","None","1.30A","3e7gA-3jblK:undetectable;3e7gB-3jblK:undetectable","3e7gA-3jblK:19.30;3e7gB-3jblK:19.30"],["3E7G_B_H4BB1902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"TRP K 954;PHE K 972;MET K 958;ILE K 924","None","1.28A","3e7gA-3jblK:undetectable;3e7gB-3jblK:undetectable","3e7gA-3jblK:19.30;3e7gB-3jblK:19.30"],["3E7G_C_H4BC2902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"MET K 958;ILE K 924;TRP K 954;PHE K 972","None","1.23A","3e7gC-3jblK:undetectable;3e7gD-3jblK:undetectable","3e7gC-3jblK:19.30;3e7gD-3jblK:19.30"],["3EJ8_A_H4BA1902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"MET K 958;ILE K 924;TRP K 954;PHE K 972","None","1.32A","3ej8A-3jblK:0.0;3ej8B-3jblK:0.0","3ej8A-3jblK:19.62;3ej8B-3jblK:19.62"],["3EJ8_D_H4BD4902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"TRP K 954;PHE K 972;MET K 958;ILE K 924","None","1.26A","3ej8C-3jblK:0.0;3ej8D-3jblK:0.0","3ej8C-3jblK:19.62;3ej8D-3jblK:19.62"],["3JW5_A_TOPA208_1","DIHYDROFOLATE REDUCTASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"LEU K 704;LEU K 666;VAL K 664;ILE K 677;PHE K 684","None","1.12A","3jw5A-3jblK:undetectable","3jw5A-3jblK:10.81"],["3KP2_B_PNNB5002_0","TRANSCRIPTIONAL REGULATOR TCAR","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ASN K 670;ALA K 698;ALA K 699;ARG K 703","None","1.22A","3kp2B-3jblK:undetectable","3kp2B-3jblK:10.19"],["3UQ6_B_ADNB401_2","ADENOSINE KINASE, PUTATIVE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"LEU K 293;GLY K 291;MET K 274;ASN K 268","None","1.33A","3uq6B-3jblK:undetectable","3uq6B-3jblK:17.37"],["4F4D_A_CHDA504_0","FERROCHELATASE, MITOCHONDRIAL","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"LEU K 796;LEU K 768;LEU K 741;ILE K 811;THR K 733","None","1.25A","4f4dA-3jblK:undetectable","4f4dA-3jblK:17.17"],["4F8H_A_RKEA401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ASP K 727;ASP K 728;VAL K 719;LEU K 746","None","1.06A","4f8hA-3jblK:undetectable;4f8hB-3jblK:undetectable","4f8hA-3jblK:16.03;4f8hB-3jblK:16.03"],["4F8H_C_RKEC401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ASP K 727;ASP K 728;VAL K 719;LEU K 746","None","1.09A","4f8hC-3jblK:undetectable;4f8hD-3jblK:undetectable","4f8hC-3jblK:16.03;4f8hD-3jblK:16.03"],["4F8H_D_RKED401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ASP K 727;ASP K 728;VAL K 719;LEU K 746","None","1.07A","4f8hD-3jblK:undetectable;4f8hE-3jblK:undetectable","4f8hD-3jblK:16.03;4f8hE-3jblK:16.03"],["4F8H_E_RKEE401_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"VAL K 719;LEU K 746;ASP K 727;ASP K 728","None","1.10A","4f8hA-3jblK:undetectable;4f8hE-3jblK:undetectable","4f8hA-3jblK:16.03;4f8hE-3jblK:16.03"],["4L1X_A_STRA402_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"LEU K 931;VAL K 960;LEU K 909;LEU K 939","None","0.96A","4l1xA-3jblK:undetectable","4l1xA-3jblK:16.29"],["4NJG_A_SAMA302_0","7-CARBOXY-7-DEAZAGUANINE SYNTHASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"GLU K 542;GLU K 720;VAL K 523;ASP K 544;GLN K 543","None","1.50A","4njgA-3jblK:1.7","4njgA-3jblK:12.63"],["4NJG_B_SAMB302_0","7-CARBOXY-7-DEAZAGUANINE SYNTHASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"GLU K 542;GLU K 720;VAL K 523;ASP K 544;GLN K 543","None","1.50A","4njgB-3jblK:1.4","4njgB-3jblK:12.63"],["4NOS_B_H4BB1011_1","INDUCIBLE NITRIC OXIDE SYNTHASE;INDUCIBLE NITRIC OXIDE SYNTHASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"TRP K 954;PHE K 972;MET K 958;ILE K 924","None","1.26A","4nosA-3jblK:undetectable;4nosB-3jblK:undetectable","4nosA-3jblK:19.27;4nosB-3jblK:19.27"],["4NOS_C_H4BC2011_1","INDUCIBLE NITRIC OXIDE SYNTHASE;INDUCIBLE NITRIC OXIDE SYNTHASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"MET K 958;ILE K 924;TRP K 954;PHE K 972","None","1.27A","4nosC-3jblK:undetectable;4nosD-3jblK:undetectable","4nosC-3jblK:19.27;4nosD-3jblK:19.27"],["4OK1_A_198A1001_2","ANDROGEN RECEPTOR","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"LEU K 847;ASN K 843;MET K 808;LEU K 787","None","0.97A","4ok1A-3jblK:undetectable","4ok1A-3jblK:15.69"],["4OLB_A_TRPA902_0","PROTEIN ARGONAUTE-2","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"TYR K 487;LYS K 476;LEU K 398;GLU K 399","None","1.41A","4olbA-3jblK:2.1","4olbA-3jblK:21.42"],["4PST_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",3,"ILE K 669;ASP K 615;ARG K 619","None","0.72A","4pstA-3jblK:undetectable","4pstA-3jblK:9.76"],["4RTS_A_SAMA301_0","DNA ADENINE METHYLASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",5,"GLY K1004;PHE K 972;GLY K 946;ILE K 924;ASP K 971","None","1.25A","4rtsA-3jblK:undetectable","4rtsA-3jblK:16.40"],["5G48_A_1FLA1375_1","DNA POLYMERASE III SUBUNIT BETA","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"THR K 278;ILE K 287;PRO K 164;LEU K 166","None","0.81A","5g48A-3jblK:undetectable","5g48A-3jblK:19.34"],["5HS1_A_VORA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"PHE K 957;GLY K 928;LEU K 912;LEU K 939","None","0.87A","5hs1A-3jblK:undetectable","5hs1A-3jblK:19.55"],["5VKQ_C_PCFC1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"ILE K 677;ILE K 591;LEU K 614;PHE K 596","None","1.03A","5vkqC-3jblK:undetectable;5vkqD-3jblK:undetectable","5vkqC-3jblK:20.32;5vkqD-3jblK:20.32"],["5WEA_A_IPHA901_0","PROTEIN ARGONAUTE-2","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"LEU K 455;TYR K 487;LEU K 398;GLU K 399","None","1.23A","5weaA-3jblK:2.1","5weaA-3jblK:21.33"],["6GBN_C_ADNC501_2","-","3jbl","NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4","Mus musculus",4,"THR K 281;THR K 337;HIS K 443;GLY K 425","None","1.07A","6gbnC-3jblK:undetectable","6gbnC-3jblK:19.50"]]