SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jbr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.78A 1c9sI-3jbrF:
undetectable
1c9sJ-3jbrF:
undetectable		 1c9sI-3jbrF:
5.20
1c9sJ-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 7 GLY F 366
THR F 364
ILE F 401
THR F 333
 None
 0.77A 1gtnA-3jbrF:
undetectable
1gtnK-3jbrF:
undetectable		 1gtnA-3jbrF:
5.20
1gtnK-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.76A 1gtnA-3jbrF:
undetectable
1gtnB-3jbrF:
undetectable		 1gtnA-3jbrF:
5.20
1gtnB-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 7 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.78A 1gtnC-3jbrF:
undetectable
1gtnD-3jbrF:
undetectable		 1gtnC-3jbrF:
5.20
1gtnD-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 6 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.75A 1gtnD-3jbrF:
undetectable
1gtnE-3jbrF:
undetectable		 1gtnD-3jbrF:
5.20
1gtnE-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.80A 1gtnE-3jbrF:
undetectable
1gtnF-3jbrF:
undetectable		 1gtnE-3jbrF:
5.20
1gtnF-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 7 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.76A 1gtnF-3jbrF:
undetectable
1gtnG-3jbrF:
undetectable		 1gtnF-3jbrF:
5.20
1gtnG-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 7 THR F 333
GLY F 366
THR F 364
ILE F 401
 None
 0.77A 1gtnJ-3jbrF:
undetectable
1gtnK-3jbrF:
undetectable		 1gtnJ-3jbrF:
5.20
1gtnK-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 GLY F 366
THR F 364
ILE F 401
THR F 333
 None
 0.76A 1gtnP-3jbrF:
undetectable
1gtnQ-3jbrF:
undetectable		 1gtnP-3jbrF:
5.20
1gtnQ-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 5 PHE F 363
LEU F 320
MET F 256
LEU F 429
 None
 1.47A 1skxA-3jbrF:
undetectable		 1skxA-3jbrF:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 GLY F 366
THR F 364
ILE F 401
THR F 333
 None
 0.80A 1utdB-3jbrF:
undetectable
1utdC-3jbrF:
undetectable		 1utdB-3jbrF:
5.20
1utdC-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 GLY F 366
THR F 364
ILE F 401
THR F 333
 None
 0.81A 1utdF-3jbrF:
undetectable
1utdG-3jbrF:
undetectable		 1utdF-3jbrF:
5.20
1utdG-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 GLY F 366
THR F 364
ILE F 401
THR F 333
 None
 0.81A 1utdI-3jbrF:
undetectable
1utdJ-3jbrF:
undetectable		 1utdI-3jbrF:
5.20
1utdJ-3jbrF:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 5 LEU F 185
ILE F 180
SER F 178
GLY F 177
 None
 0.92A 2otfA-3jbrF:
undetectable		 2otfA-3jbrF:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_B_CSCB1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		5 / 12 LEU F 508
THR F 507
GLN F 447
ASP F 289
PHE F 290
 None
 1.37A 2vavB-3jbrF:
1.5		 2vavB-3jbrF:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_I_CSCI1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		5 / 12 LEU F 508
THR F 507
GLN F 447
ASP F 289
PHE F 290
 None
 1.36A 2vavI-3jbrF:
1.5		 2vavI-3jbrF:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		5 / 12 LEU F 508
THR F 507
GLN F 447
ASP F 289
PHE F 290
 None
 1.39A 2vavJ-3jbrF:
2.1		 2vavJ-3jbrF:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 5 ASN F 615
THR F 503
SER F 621
ARG F 501
 NAG  F1203 (-2.8A)
None
None
None
 1.42A 3hlwB-3jbrF:
undetectable		 3hlwB-3jbrF:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_C_SAMC401_0
(MNMC2)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		5 / 12 GLY F 211
TYR F 246
ASN F 480
ALA F 222
LEU F 456
 None
 1.16A 3vywC-3jbrF:
undetectable		 3vywC-3jbrF:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		3 / 3 ASP F 397
GLU F 368
GLY F 367
 None
 0.69A 3w9tA-3jbrF:
undetectable		 3w9tA-3jbrF:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		3 / 3 ASN F 615
GLU F  89
ARG F  86
 NAG  F1203 (-2.8A)
None
None
 0.78A 3wxoA-3jbrF:
undetectable		 3wxoA-3jbrF:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 3jbr VOLTAGE-DEPENDENT
CALCIUM CHANNEL
SUBUNIT
ALPHA-2/DELTA-1
(Oryctolagus
cuniculus) 		4 / 8 GLY F 215
TRP F 225
VAL F 240
ASP F 239
 None
 0.98A 5vlmA-3jbrF:
undetectable		 5vlmA-3jbrF:
8.92