SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OG5_A_SWFA502_1 (CYTOCHROME P450 2C9)	3jc5	DNA REPLICATION COMPLEX GINS PROTEIN PSF3 (Saccharomyces cerevisiae)	5 / 12	PHE C 80 LEU C 75 THR C 14 LEU C 107 PHE C 16	None	1.16A	1og5A-3jc5C: 2.2	1og5A-3jc5C: 17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_A_SAMA298_0 (PUTATIVE MODIFICATION METHYLASE)	3jc5	DNA REPLICATION COMPLEX GINS PROTEIN PSF3 (Saccharomyces cerevisiae)	5 / 12	ALA C 108 SER C 81 PRO C 77 PHE C 80 GLU C 117	None	1.17A	2zifA-3jc5C: undetectable	2zifA-3jc5C: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4USW_A_ACTA1470_0 (ADENYLATE CYCLASE TYPE 10)	3jc5	DNA REPLICATION COMPLEX GINS PROTEIN PSF3 (Saccharomyces cerevisiae)	4 / 6	LEU C 46 LEU C 74 VAL C 72 PHE C 16	None	1.18A	4uswA-3jc5C: undetectable	4uswA-3jc5C: 17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FOS_A_PQNA2001_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1)	3jc5	DNA REPLICATION COMPLEX GINS PROTEIN PSF3 (Saccharomyces cerevisiae)	4 / 6	GLY C 13 TRP C 49 ALA C 51 LEU C 46	None	0.93A	6fosA-3jc5C: undetectable	6fosA-3jc5C: 16.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1OG5_A_SWFA502_1","CYTOCHROME P450 2C9","3jc5","DNA REPLICATION COMPLEX GINS PROTEIN PSF3","Saccharomyces cerevisiae",5,"PHE C  80;LEU C  75;THR C  14;LEU C 107;PHE C  16","None","1.16A","1og5A-3jc5C:2.2","1og5A-3jc5C:17.20"],["2ZIF_A_SAMA298_0","PUTATIVE MODIFICATION METHYLASE","3jc5","DNA REPLICATION COMPLEX GINS PROTEIN PSF3","Saccharomyces cerevisiae",5,"ALA C 108;SER C  81;PRO C  77;PHE C  80;GLU C 117","None","1.17A","2zifA-3jc5C:undetectable","2zifA-3jc5C:19.87"],["4USW_A_ACTA1470_0","ADENYLATE CYCLASE TYPE 10","3jc5","DNA REPLICATION COMPLEX GINS PROTEIN PSF3","Saccharomyces cerevisiae",4,"LEU C  46;LEU C  74;VAL C  72;PHE C  16","None","1.18A","4uswA-3jc5C:undetectable","4uswA-3jc5C:17.89"],["6FOS_A_PQNA2001_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1","3jc5","DNA REPLICATION COMPLEX GINS PROTEIN PSF3","Saccharomyces cerevisiae",4,"GLY C  13;TRP C  49;ALA C  51;LEU C  46","None","0.93A","6fosA-3jc5C:undetectable","6fosA-3jc5C:16.95"]]