SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3jc6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_A_ADNA503_0 (ADENOSYLHOMOCYSTEINA SE)	3jc6	DNA REPLICATION COMPLEX GINS PROTEIN PSF1 (Saccharomyces cerevisiae)	5 / 10	GLY A 6 GLY A 3 CYH A 78 ASN A 39 ILE A 36	None	1.20A	6exiA-3jc6A: undetectable	6exiA-3jc6A: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_B_ADNB503_1 (ADENOSYLHOMOCYSTEINA SE)	3jc6	DNA REPLICATION COMPLEX GINS PROTEIN PSF1 (Saccharomyces cerevisiae)	5 / 10	GLY A 6 GLY A 3 CYH A 78 ASN A 39 ILE A 36	None	1.17A	6exiB-3jc6A: undetectable	6exiB-3jc6A: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_C_ADNC503_0 (ADENOSYLHOMOCYSTEINA SE)	3jc6	DNA REPLICATION COMPLEX GINS PROTEIN PSF1 (Saccharomyces cerevisiae)	5 / 12	GLY A 6 GLY A 3 CYH A 78 ASN A 39 ILE A 36	None	1.20A	6exiC-3jc6A: undetectable 6exiD-3jc6A: undetectable	6exiC-3jc6A: 18.23 6exiD-3jc6A: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_D_ADND503_0 (ADENOSYLHOMOCYSTEINA SE)	3jc6	DNA REPLICATION COMPLEX GINS PROTEIN PSF1 (Saccharomyces cerevisiae)	5 / 12	GLY A 6 GLY A 3 CYH A 78 ASN A 39 ILE A 36	None	1.21A	6exiC-3jc6A: undetectable 6exiD-3jc6A: undetectable	6exiC-3jc6A: 18.23 6exiD-3jc6A: 18.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["6EXI_A_ADNA503_0","ADENOSYLHOMOCYSTEINASE","3jc6","DNA REPLICATION COMPLEX GINS PROTEIN PSF1","Saccharomyces cerevisiae",5,"GLY A   6;GLY A   3;CYH A  78;ASN A  39;ILE A  36","None","1.20A","6exiA-3jc6A:undetectable","6exiA-3jc6A:18.23"],["6EXI_B_ADNB503_1","ADENOSYLHOMOCYSTEINASE","3jc6","DNA REPLICATION COMPLEX GINS PROTEIN PSF1","Saccharomyces cerevisiae",5,"GLY A   6;GLY A   3;CYH A  78;ASN A  39;ILE A  36","None","1.17A","6exiB-3jc6A:undetectable","6exiB-3jc6A:18.23"],["6EXI_C_ADNC503_0","ADENOSYLHOMOCYSTEINASE","3jc6","DNA REPLICATION COMPLEX GINS PROTEIN PSF1","Saccharomyces cerevisiae",5,"GLY A   6;GLY A   3;CYH A  78;ASN A  39;ILE A  36","None","1.20A","6exiC-3jc6A:undetectable;6exiD-3jc6A:undetectable","6exiC-3jc6A:18.23;6exiD-3jc6A:18.23"],["6EXI_D_ADND503_0","ADENOSYLHOMOCYSTEINASE","3jc6","DNA REPLICATION COMPLEX GINS PROTEIN PSF1","Saccharomyces cerevisiae",5,"GLY A   6;GLY A   3;CYH A  78;ASN A  39;ILE A  36","None","1.21A","6exiC-3jc6A:undetectable;6exiD-3jc6A:undetectable","6exiC-3jc6A:18.23;6exiD-3jc6A:18.23"]]